Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
100-17-4	4-Nitroanisole	>99	202-825-3

Section 3 - Hazards Identification

Appearance: colorless solid.
Warning! May cause eye, skin, and respiratory tract irritation. May be absorbed through intact skin.
Target Organs: None known.


Potential Health Effects
Eye: May cause eye irritation. May cause eye burns.
Skin: May cause skin irritation. If absorbed, causes symptoms similar to those of ingestion. May cause skin burns. Effects may be delayed.
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: Effects may be delayed. May cause respiratory tract irritation.
Chronic: Not available.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: For large fires, use water spray, fog, or alcohol-resistant foam. For small fires, use dry chemical, carbon dioxide, halon, or water spray.
Flash Point: 130 deg C ( 266.00 deg F)
Autoignition Temperature: 458 deg C ( 856.40 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: ; Flammability: 1; Instability:

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Do not get water inside containers.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
4-Nitroanisole	none listed	none listed	none listed

OSHA Vacated PELs: 4-Nitroanisole: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 260 deg C
Freezing/Melting Point:54 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:1.2330
Molecular Formula:C7H7NO3
Molecular Weight:153.14

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Dust generation.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:      
CAS# 100-17-4: BZ8800000
LD50/LC50:
CAS# 100-17-4:
     Oral, rat: LD50 = 2300 mg/kg;
     Skin, rat: LD50 = >16 gm/kg;
.

Carcinogenicity:
CAS# 100-17-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: Mutation data has been reported.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: No data available. Water danger/protection: WGK2 Invertebrate toxicity: EC50 (24 hr) Daphnia magna 13 mg/l (nominal value) [Kuehn, R. et al Water Res. 1989, 23(4), 501-510]
Environmental: Bioaccumulation: Non- or low accumulative.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	NITROANISOLE	NITROANISOLES, SOLID
Hazard Class:	6.1	6.1
UN Number:	UN2730	UN2730
Packing Group:	III	III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 100-17-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 100-17-4 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN
Risk Phrases:
     R 40 Limited evidence of a carcinogenic effect.

Safety Phrases:
     S 36/37 Wear suitable protective clothing and gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)
     CAS# 100-17-4: 1
Canada - DSL/NDSL
     CAS# 100-17-4 is listed on Canada's NDSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 100-17-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 9/30/1997
Revision #5 Date: 9/26/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.