Material Safety Data Sheet
Dichloromethane-d2

ACC# 96515
Section 1 - Chemical Product and Company Identification
MSDS Name: Dichloromethane-d2
Catalog Numbers: AC176110000, AC176110050, AC176110250, AC214550000, AC214550050, AC217350000 AC217350000, AC217350010, AC217350100, AC217430000, AC217430010, AC217430050 AC217430050, AC320720000, AC320720075, AC321270000, AC321270010, AC321270050 AC321270050, AC321270100
Synonyms: Methylene chloride-d.
Company Identification:
              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
1665-00-5 Dichloromethane-d2 99.6+ 216-776-0

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid.
Warning! Possible cancer hazard. May cause cancer based on animal data. Harmful if inhaled or swallowed. Causes eye, skin, and respiratory tract irritation. May cause central nervous system effects. Hygroscopic (absorbs moisture from the air).
Target Organs: Blood, kidneys, heart, central nervous system, liver, respiratory system, gastrointestinal system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion: Harmful if swallowed. Causes gastrointestinal tract irritation.
Inhalation: Harmful if inhaled. Causes respiratory tract irritation. May cause cardiac damage. May cause central nervous system effects.
Chronic: Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage. Adverse reproductive effects have been reported in animals. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause blood effects. Animal studies have reported the development of tumors. Limited evidence of a carcinogenic effect.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: 605 deg C ( 1,121.00 deg F)
Explosion Limits, Lower:13 vol %
Upper: 22 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 1

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Provide ventilation. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Store in a tightly closed container. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Dichloromethane-d2 none listed none listed none listed
Methylene chloride 50 ppm TWA 2300 ppm IDLH 25 ppm TWA; 12.5 ppm Action Level; 25 ppm TWA; 125 ppm STEL (15 min, Cancer, cardiac effects , central nervous system effects, liver effects, and skin and eye irritation - See 29 CFR 1910.1052)

OSHA Vacated PELs: Dichloromethane-d2: No OSHA Vacated PELs are listed for this chemical. Methylene chloride: 500 ppm TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: none reported
pH: Not available.
Vapor Pressure: 450 hPa @ 20 deg C
Vapor Density: 2.93 (Air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 40 deg C @ 760 mmHg
Freezing/Melting Point:-97 deg C
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:1.360
Molecular Formula:CCl2D2
Molecular Weight:86.95

Section 10 - Stability and Reactivity


Chemical Stability: Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid: Incompatible materials, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, alkali metals, aluminum.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 1665-00-5 unlisted.      
CAS# 75-09-2: PA8050000
LD50/LC50:
Not available.

CAS# 75-09-2:
     Draize test, rabbit, eye: 162 mg Moderate;
     Draize test, rabbit, eye: 10 mg Mild;
     Draize test, rabbit, eye: 500 mg/24H Mild;
     Draize test, rabbit, skin: 810 mg/24H Severe;
     Draize test, rabbit, skin: 100 mg/24H Moderate;
     Inhalation, mouse: LC50 = 14400 ppm/7H;
     Inhalation, mouse: LC50 = 49100 mg/m3/6H;
     Inhalation, mouse: LC50 = 54000 mg/m3/2H;
     Inhalation, mouse: LC50 = 56220 mg/m3/7H;
     Inhalation, rat: LC50 = 52 gm/m3;
     Inhalation, rat: LC50 = 76000 mg/m3/4H;
     Inhalation, rat: LC50 =
Carcinogenicity:
CAS# 1665-00-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 75-09-2:


Epidemiology: Tumorigenic effects have been reported in experimental animals.
Teratogenicity: Teratogenic effects have occurred in experimental animals.
Reproductive Effects: Adverse reproductive effects have occurred in experimental animals.
Mutagenicity: Mutagenic effects have occurred in humans.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Bluegill/Sunfish: 230mg/L; 24H; StaticFish: Fathead Minnow: 196mg/L; 96H; This chemical has a moderate potential to affect some aquatic organisms. It is resistant to biodegradation, and has a low potential to persist in the aquatic environment. 96-hr. EC50 (loss of equilibrium); Fathead minnow: 99mg/L; 96-hr. EC10: 66.3 mg/L. Bluegill sunfish: 96-hr. LC50=220 mg/L; Water flea: 24-hr. LC50=2270 mg/L; No observed effect level:1550 mg/L.
Environmental: Terrestrial: Expected to evaporate from near surface soil into the atmosphere; expected to leach. Aquatic: Primarily lost by evaporation to the atmosphere which should take several hours depending on wind and mixing conditions. Atmospheric: Will degrade by reaction with hydroxyl radicals with a half life of several months. . Dichloromethane is reported to completely biodegrade under aerobic conditions with sewage seed or activated sludge between 6 hours to 7 days. Not expected to bioconcentrate due to its low octanol/water coefficient.
Physical: No information available.
Other: For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 75-09-2: waste number U080.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: DICHLOROMETHANE DICHLOROMETHANE
Hazard Class: 6.1 6.1
UN Number: UN1593 UN1593
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 1665-00-5 is not listed on the TSCA inventory. It is for research and development use only.
     CAS# 75-09-2 is listed on the TSCA inventory.
Health & Safety Reporting List
     CAS# 75-09-2: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     CAS# 75-09-2: Section 4, 0.1 % de minimus concentration
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 75-09-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 75-09-2: immediate, delayed.
Section 313
     This material contains Methylene chloride (CAS# 75-09-2, -%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 75-09-2 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.      CAS# 75-09-2 is listed as a Priority Pollutant under the Clean Water      Act. CAS# 75-09-2 is listed as a Toxic Pollutant under the Clean Water Act.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 1665-00-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 75-09-2 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65
WARNING: This product contains Methylene chloride, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: CAS# 75-09-2: 200 ęg/day NSRL (inhalation); 50 ęg/day NSRL (except inhalation)

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN
Risk Phrases:
     R 40 Limited evidence of a carcinogenic effect.

Safety Phrases:
     S 23 Do not inhale gas/fumes/vapour/spray.
     S 24/25 Avoid contact with skin and eyes.
     S 36/37 Wear suitable protective clothing and gloves.

WGK (Water Danger/Protection)
     CAS# 1665-00-5: No information available.
     CAS# 75-09-2: 2
Canada - DSL/NDSL
     CAS# 75-09-2 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D2A.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 75-09-2 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 8/24/1997
Revision #7 Date: 1/25/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.