Material Safety Data Sheet
MSDS Name: Dichloromethane-d2
Section 1 - Chemical Product and Company Identification
AC176110000, AC176110050, AC176110250, AC214550000, AC214550050, AC217350000
AC217350000, AC217350010, AC217350100, AC217430000, AC217430010, AC217430050
AC217430050, AC320720000, AC320720075, AC321270000, AC321270010, AC321270050
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|| 99.6+ ||216-776-0
Section 3 - Hazards Identification
Appearance: clear, colorless liquid.
Warning! Possible cancer hazard. May cause cancer
based on animal data. Harmful if inhaled or swallowed. Causes eye,
skin, and respiratory tract irritation. May cause central nervous
system effects. Hygroscopic (absorbs moisture from the air).
Target Organs: Blood, kidneys, heart, central
nervous system, liver, respiratory system, gastrointestinal system,
Potential Health Effects
Causes eye irritation.
Causes skin irritation. May be harmful if absorbed through the skin.
Harmful if swallowed. Causes gastrointestinal tract irritation.
Harmful if inhaled. Causes respiratory tract irritation. May cause
cardiac damage. May cause central nervous system effects.
Possible cancer hazard based on tests with laboratory animals. May
cause liver and kidney damage. Adverse reproductive effects have been
reported in animals. Laboratory experiments have resulted in
mutagenic effects. Chronic exposure may cause blood effects. Animal
studies have reported the development of tumors. Limited evidence of
a carcinogenic effect.
Section 4 - First Aid Measures
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
Do not induce vomiting. Get medical aid immediately. Call a poison
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do not use
mouth-to-mouth resuscitation if victim ingested or inhaled the
substance; induce artificial respiration with the aid of a pocket
mask equipped with a one-way valve or other proper respiratory
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: 605 deg C ( 1,121.00 deg F)
Explosion Limits, Lower:13 vol %
Upper: 22 vol %
(estimated) Health: 2; Flammability: 1; Instability: 1
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Wear a self contained breathing
apparatus and appropriate personal protection. (See Exposure
Controls, Personal Protection section). Provide ventilation. Do not
let this chemical enter the environment.
Section 7 - Handling and Storage
Do not get in eyes, on skin, or on clothing. Do not ingest or
inhale. Use only in a chemical fume hood.
Store in a cool, dry place. Store in a tightly closed container.
Store under an inert atmosphere.
Section 8 - Exposure Controls, Personal Protection
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use only under a
chemical fume hood.
||OSHA - Final PELs|
50 ppm TWA
2300 ppm IDLH
25 ppm TWA; 12.5 ppm Action Level; 25 ppm TWA; 125 ppm STEL (15 min, Cancer, cardiac effects , central nervous system effects, liver effects, and skin and eye irritation - See 29 CFR 1910.1052)
OSHA Vacated PELs:
No OSHA Vacated PELs are listed for this chemical.
500 ppm TWA
Personal Protective Equipment
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: none reported
pH: Not available.
Vapor Pressure: 450 hPa @ 20 deg C
Vapor Density: 2.93 (Air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 40 deg C @ 760 mmHg
Freezing/Melting Point:-97 deg C
Decomposition Temperature:Not available.
Solubility: Not available.
Section 10 - Stability and Reactivity
Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid:
Incompatible materials, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, alkali metals, aluminum.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
rabbit, eye: 162 mg Moderate;
Draize test, rabbit, eye: 10 mg
Draize test, rabbit, eye: 500
Draize test, rabbit,
skin: 810 mg/24H Severe;
test, rabbit, skin: 100 mg/24H Moderate;
Inhalation, mouse: LC50 = 14400
Inhalation, mouse: LC50 =
LC50 = 54000 mg/m3/2H;
mouse: LC50 = 56220 mg/m3/7H;
Inhalation, rat: LC50 = 52 gm/m3;
Inhalation, rat: LC50 = 76000
Inhalation, rat: LC50 =
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
- ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
- California: carcinogen, initial date 4/1/88
- NTP: Suspect carcinogen
- IARC: Group 2B carcinogen
Tumorigenic effects have been reported in experimental
Teratogenic effects have occurred in experimental animals.
Adverse reproductive effects have occurred in experimental
Mutagenic effects have occurred in humans.
No information found
Section 12 - Ecological Information
Fish: Bluegill/Sunfish: 230mg/L; 24H; StaticFish: Fathead Minnow:
This chemical has a moderate potential to affect some aquatic
organisms. It is resistant to biodegradation, and has a low potential
to persist in the aquatic environment. 96-hr. EC50 (loss of
equilibrium); Fathead minnow: 99mg/L; 96-hr. EC10: 66.3 mg/L.
Bluegill sunfish: 96-hr. LC50=220 mg/L; Water flea: 24-hr. LC50=2270
mg/L; No observed effect level:1550 mg/L.
Terrestrial: Expected to evaporate from near surface soil into the
atmosphere; expected to leach. Aquatic: Primarily lost by
evaporation to the atmosphere which should take several hours
depending on wind and mixing conditions. Atmospheric: Will degrade
by reaction with hydroxyl radicals with a half life of several
months. . Dichloromethane is reported to completely biodegrade under
aerobic conditions with sewage seed or activated sludge between 6
hours to 7 days. Not expected to bioconcentrate due to its low
No information available.
For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
CAS# 75-09-2: waste
Section 14 - Transport Information
Section 15 - Regulatory Information
CAS# 1665-00-5 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 75-09-2 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 75-09-2: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
CAS# 75-09-2: Section 4, 0.1 % de minimus concentration
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 75-09-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 75-09-2: immediate, delayed.
This material contains Methylene
chloride (CAS# 75-09-2, -%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 75-09-2 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
CAS# 75-09-2 is listed as a Priority Pollutant under the Clean Water
CAS# 75-09-2 is listed as a Toxic Pollutant under the Clean Water
None of the chemicals in this product
are considered highly hazardous by OSHA.
CAS# 1665-00-5 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 75-09-2 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
WARNING: This product contains Methylene chloride, a chemical known
to the state of California to cause cancer.
California No Significant Risk Level:
CAS# 75-09-2: 200 ęg/day NSRL (inhalation); 50 ęg/day NSRL
European Labeling in Accordance with EC Directives
R 40 Limited evidence of a carcinogenic effect.
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
S 36/37 Wear suitable protective clothing and gloves.
WGK (Water Danger/Protection)
CAS# 1665-00-5: No information available.
CAS# 75-09-2: 2
Canada - DSL/NDSL
CAS# 75-09-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 75-09-2 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
MSDS Creation Date: 8/24/1997
Revision #7 Date: 1/25/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.