Material Safety Data Sheet
n-Propyl acetate

ACC# 97171
Section 1 - Chemical Product and Company Identification

MSDS Name: n-Propyl acetate
Catalog Numbers: AC158290000, AC158290010, AC158290025, AC158290100, AC158291000, AC158295000, AC180840000, AC180840025, AC180840050, AC180845000, AC418410000, AC418410010, AC418410030, AC418410200, EK1083120, EK1083138
Synonyms:
Acetic acid n-propyl ester; 1-Acetoxypropane.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
109-60-4 n-Propyl acetate 90+ 203-686-1

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: APHA: 15 max liquid. Flash Point: 10 deg C.
Danger! Flammable liquid and vapor. Causes eye, skin, and respiratory tract irritation. Breathing vapors may cause drowsiness and dizziness. Repeated exposure may cause skin dryness or cracking.
Target Organs: Blood, central nervous system, respiratory system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause central nervous system depression.
Inhalation: Causes respiratory tract irritation. May cause narcotic effects in high concentration. May be harmful if inhaled. Inhalation of vapors may cause drowsiness and dizziness.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis. Chronic exposure may cause blood effects.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Containers may explode in the heat of a fire. Flammable liquid and vapor.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Water may be ineffective.
Flash Point: 10 deg C ( 50.00 deg F)
Autoignition Temperature: 450 deg C ( 842.00 deg F)
Explosion Limits, Lower:1.8 vol %
Upper: 8 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 1

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Use a spark-proof tool. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
n-Propyl acetate 200 ppm TWA; 250 ppm STEL 200 ppm TWA; 840 mg/m3 TWA 1700 ppm IDLH 200 ppm TWA; 840 mg/m3 TWA

OSHA Vacated PELs: n-Propyl acetate: 200 ppm TWA; 840 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless - APHA: 15 max
Odor: odor of pears
pH: Not available.
Vapor Pressure: 33 mbar @ 20 deg C
Vapor Density: 3.5 (air=1)
Evaporation Rate:Not available.
Viscosity: 0.58 mPa @ 20 deg C
Boiling Point: 102 deg C @ 760 mmHg
Freezing/Melting Point:-95 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:0.880
Molecular Formula:C5H10O2
Molecular Weight:102.13

Section 10 - Stability and Reactivity


Chemical Stability: Moisture sensitive.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases.
Hazardous Decomposition Products: Carbon monoxide, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 109-60-4: AJ3675000
LD50/LC50:
CAS# 109-60-4:
     Draize test, rabbit, eye: 500 mg/24H Mild;
     Oral, mouse: LD50 = 8300 mg/kg;
     Oral, rabbit: LD50 = 6640 mg/kg;
     Oral, rat: LD50 = 9370 mg/kg;
     Skin, rabbit: LD50 = >20 mL/kg;
.

Carcinogenicity:
CAS# 109-60-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Fathead Minnow: 60mg/L; 96H; No data available.
Environmental: Terrestrial: Expected to have high mobility in soil. Volatilization is expected from moist soil surfaces. Aquatic: Not expected to adsorb to suspended solids and sediment in water. Expected to volatilize from water surfaces. Atmospheric: Expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; half-life estimated to be about 5 days. Expected to slightly biodegrade and bioconcentrate.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: N-PROPYL ACETATE N-PROPYL ACETATE
Hazard Class: 3 3
UN Number: UN1276 UN1276
Packing Group: II II
Additional Info:FLASHPOINT 10 C

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 109-60-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 109-60-4: immediate, fire.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 109-60-4 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     XI F
Risk Phrases:

     R 11 Highly flammable.
     R 36 Irritating to eyes.
     R 66 Repeated exposure may cause skin dryness or cracking.
     R 67 Vapours may cause drowsiness and dizziness.

Safety Phrases:

     S 16 Keep away from sources of ignition - No smoking.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 29 Do not empty into drains.
     S 33 Take precautionary measures against static discharges.

WGK (Water Danger/Protection)

     CAS# 109-60-4: 1
Canada - DSL/NDSL
     CAS# 109-60-4 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 109-60-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 7/28/1999
Revision #6 Date: 4/03/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.