Material Safety Data Sheet
Ethylbenzene

ACC# 00596
Section 1 - Chemical Product and Company Identification

MSDS Name: Ethylbenzene
Catalog Numbers: AC118080000, AC118080025, AC118080250, AC118080251, AC118085000, 11808-0010, O2751-1
Synonyms: Ethylbenzol; Phenylethane.
Company Identification:
              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
100-41-4 Ethylbenzene >99 202-849-4

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid. Flash Point: 15 deg C.
Warning! Flammable liquid and vapor. Causes eye, skin, and respiratory tract irritation. May be harmful if inhaled. Aspiration hazard if swallowed. Can enter lungs and cause damage. May cause central nervous system depression.
Target Organs: Central nervous system.


Potential Health Effects
Eye: Causes severe eye irritation. Causes redness and pain.
Skin: Causes skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. May be absorbed through the skin. Causes redness and pain.
Ingestion: May cause irritation of the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.
Chronic: Chronic inhalation may cause effects similar to those of acute inhalation.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire. May accumulate static electricity.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 15 deg C ( 59.00 deg F)
Autoignition Temperature: 432 deg C ( 809.60 deg F)
Explosion Limits, Lower:1.2%
Upper: 6.8%
NFPA Rating: (estimated) Health: 2; Flammability: 3; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Provide ventilation. Control runoff and isolate discharged material for proper disposal. Use water spray to cool and disperse vapors and protect personnel.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Avoid breathing vapor or mist.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Ethylbenzene 100 ppm TWA; 125 ppm STEL 100 ppm TWA; 435 mg/m3 TWA 800 ppm IDLH 100 ppm TWA; 435 mg/m3 TWA

OSHA Vacated PELs: Ethylbenzene: 100 ppm TWA; 435 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: aromatic odor
pH: Not available.
Vapor Pressure: 9.6 mm Hg @ 25 deg C
Vapor Density: 3.7 (air=1)
Evaporation Rate:<1 (butyl acetate=1)
Viscosity: 0.63 mPa s 20 C
Boiling Point: 136 deg C
Freezing/Melting Point:-95 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:0.86
Molecular Formula:C8H10
Molecular Weight:106.17

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 100-41-4: DA0700000
LD50/LC50:
CAS# 100-41-4:
     Draize test, rabbit, eye: 500 mg Severe;
     Inhalation, mouse: LC50 = 35500 mg/m3/2H;
     Inhalation, rat: LC50 = 55000 mg/m3/2H;
     Oral, rat: LD50 = 3500 mg/kg;
     Oral, rat: LD50 = 3500 mg/kg;
     Skin, rabbit: LD50 = 17800 uL/kg;
.
Inhalation rat LC50: 17.2 mg/l/4H from BASF.
Carcinogenicity:
CAS# 100-41-4:


Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: Mutation in mammalian somatic cells(Rodent,mouse) Lymphocyte = 80 mg/L.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Rainbow trout: LC50 = 14.0 mg/L; 96 Hr.; Static BioassayFish: Fathead Minnow: LC50 = 12.1 mg/L; 96 Hr.; Flow-through BioassayFish: Bluegill/Sunfish: LC50 = 150.0 mg/L; 96 Hr.; Static Bioassay, pH 6.5-7.9, 21-23 degrees CWater flea EC50 = 2.1 mg/L; 48 Hr.; Static BioassayWater flea EC50 = 75.0 mg/L; 48 Hr.; Static Bioassay Shrimp (mysidoposis bahia), LC50=87.6 mg/L/96hr. Sheepshead minnow LC50=275 mg/L/96hr. Fathead minnow LC50=42.3 mg/L/96hr in hard water &48.5 mg/L/96hr in softwater.
Environmental: Experimental data on the bioconcentration of ethylbenzene include a log BCF of 1.9 in goldfish and the log BCF of 0.67 for clams exposed to the water-soluble fraction of crude oil. Using its octanol/water partition coefficient (log Kow= 3.15) and using a recommended regression equation, one can calculate a log BCF in fish of 2.16 indicating that ethylbenzene should not significantly bioconcentrate in aquatic organisms. Ethylbenzene has a moderate adsorption for soil. The measured Koc for silt loam was 164
Physical: The predominant photochemical reaction of ethylbenzene in the atmosphere is with hydroxyl radicals; the tropospheric half-life for this reaction is 5.5 and 24 hr in the summer and winter, actively. Degradation is somewhat faster under photochemical smog situations. Photooxidation products which have been identified include ethylphenol, benzaldehyde, acetophenone and m- and p-ethylnitrobenzene. Ethylbenzene is resistant to hydrolysis. Ethylbenzene does not significantly absorb light above 290 nm in methanol solution.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: ETHYLBENZENE ETHYLBENZENE
Hazard Class: 3 3
UN Number: UN1175 UN1175
Packing Group: II II
Additional Info:FLASHPOINT 15 C

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 100-41-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     CAS# 100-41-4: Effective 6/19/87, Sunset 6/19/97
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 100-41-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 100-41-4: immediate, delayed, fire.
Section 313
     This material contains Ethylbenzene (CAS# 100-41-4, >99%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 100-41-4 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 100-41-4 is listed as a Hazardous Substance under the CWA.      CAS# 100-41-4 is listed as a Priority Pollutant under the Clean Water      Act. CAS# 100-41-4 is listed as a Toxic Pollutant under the Clean Water Act.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 100-41-4 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains Ethylbenzene, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN F
Risk Phrases:
     R 11 Highly flammable.
     R 20 Harmful by inhalation.

Safety Phrases:
     S 16 Keep away from sources of ignition - No smoking.
     S 24/25 Avoid contact with skin and eyes.
     S 29 Do not empty into drains.

WGK (Water Danger/Protection)
     CAS# 100-41-4: 1
Canada - DSL/NDSL
     CAS# 100-41-4 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, D2B, D2A.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 100-41-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 4/28/1999
Revision #6 Date: 11/29/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.