Material Safety Data Sheet
1-Chloro-3-nitrobenzene, 98%
ACC# 00702
Section 1 - Chemical Product and Company Identification |
MSDS Name: 1-Chloro-3-nitrobenzene, 98%
Catalog Numbers:
AC203990010, AC203990050, AC203991000, AC203992500, AC203995000
Synonyms:
m-Chloronitrobenzene; m-Nitrochlorobenzene.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
121-73-3 |
1-Chloro-3-nitrobenzene |
98 | 204-496-1 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: tan crystalline powder.
Warning! Harmful if swallowed. May cause allergic
skin reaction. May cause eye, skin, and respiratory tract
irritation. Aspiration hazard if swallowed. Can enter lungs and
cause damage. May cause cancer based on animal studies. May cause
central nervous system effects. May cause cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood). May
cause liver and kidney damage.
Target Organs: Kidneys, central nervous system,
liver.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. Aspiration of material into the lungs may
cause chemical pneumonitis, which may be fatal. May cause central
nervous system depression. May cause cyanosis (bluish discoloration
of skin due to deficient oxygenation of the blood).
Inhalation:
May cause effects similar to those described for ingestion.
Chronic:
May cause liver and kidney damage. May cause anemia and other blood
cell abnormalities. May cause fatigue, dizziness, headache, insomnia
and weight loss.
Section 4 - First Aid Measures
|
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use agent most appropriate to extinguish
fire.
Flash Point: 103 deg C ( 217.40 deg F)
Autoignition Temperature: > 450 deg C (> 842.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Remove all sources of
ignition. Provide ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Avoid contact with skin and eyes. Do
not ingest or inhale.
Storage:
Keep container closed when not in use. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
1-Chloro-3-nitrobenzene
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
1-Chloro-3-nitrobenzene:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Crystalline powder
Appearance: tan
Odor: None reported.
pH: Not available.
Vapor Pressure: <0.1 mbar @ 20
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 236 deg C @ 760.00mm Hg
Freezing/Melting Point:42 - 44 deg C
Decomposition Temperature:> 300 deg C
Solubility: soluble in most common organic solvents
Specific Gravity/Density:1.5340g/cm3
Molecular Formula:C6H4ClNO2
Molecular Weight:157.56
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, ammonia.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide, nitrogen gas.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 121-73-3:
CZ0940000
LD50/LC50:
CAS# 121-73-3:
Oral, mouse: LD50 =
380 mg/kg;
Oral, rat: LD50 = 420
mg/kg;
.
Carcinogenicity:
CAS# 121-73-3:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
Has been found to cause cancer in laboratory animals.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
No information available.
Neurotoxicity:
No information available.
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
No information available.
Environmental:
Terrestrial: M-Chloronitrobenzene does not contain a readily
hydrolyzable functional group. Therefore, hydrolysis of
m-chloronitrobenzene in soil is not significant. Aquatic:
m-Chloronitrobenzene does not contain any readily hydrolyzable
functional groups and is unlikely to undergo hydrolysis as a major
fate. Atmospheric: Based on a vapor pressure of 0.035 mm Hg at 25C
m-chloronitrobenzene process. Slight biodegradation but significant
bioconcentration. likely to be a significant fate process. Sorption
of m-chloronitrobenzene to
Physical:
No information available.
Other:
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
CHLORONITROBENZENES, SOLID |
CHLORONITOBENZENES |
Hazard Class: |
6.1 |
6.1 |
UN Number: |
UN1578 |
UN1578 |
Packing Group: |
II |
II |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 121-73-3 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 121-73-3 can be found on the
following state right to know lists: Pennsylvania, Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 25 Toxic if swallowed.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 38 In case of insufficient ventilation, wear suitable respiratory
equipment.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 28A After contact with skin, wash immediately with plenty of water
.
WGK (Water Danger/Protection)
CAS# 121-73-3: 2
Canada - DSL/NDSL
CAS# 121-73-3 is listed on Canada's NDSL List.
Canada - WHMIS
not available.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 121-73-3 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 2/09/1999
Revision #4 Date: 11/13/2006
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.