Material Safety Data Sheet
2-Ethoxyethyl acetate 99%
ACC# 01751
Section 1 - Chemical Product and Company Identification |
MSDS Name: 2-Ethoxyethyl acetate 99%
Catalog Numbers:
AC149420000, AC149420025, AC149420050
Synonyms:
2-Ethoxyethyl acetate; Oxitol acetate; Cellosolve acetate; Ethylene
glycol monoethyl ether acetate; EGEEA; Ethylene glycol ethyl ether
acetate.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
111-15-9 |
2-Ethoxyethyl acetate |
99.0 | 203-839-2 |
7732-18-5 |
Water |
< 0.05 | 231-791-2 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 51 deg C.
Warning! Flammable liquid and
vapor. Causes eye irritation. Causes respiratory tract
irritation. May be harmful if swallowed, inhaled, or absorbed through
the skin. May cause skin irritation. May cause blood abnormalities.
May form explosive peroxides. This material has been reported to be
susceptible to autoxidation and therefore should be classified as
peroxidizable. May cause central nervous system depression. May cause
liver and kidney damage. Possible birth defect hazard. May cause
birth defects based on animal data. May cause reproductive and fetal
effects.
Target Organs: Blood, kidneys, central nervous
system, liver, reproductive system.
Potential Health Effects
Eye:
May cause eye irritation. May cause chemical conjunctivitis and
corneal damage.
Skin:
May cause skin irritation. May be absorbed through the skin. May
cause irritation and dermatitis. May cause cyanosis of the
extremities.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause central nervous system depression, characterized
by excitement, followed by headache, dizziness, drowsiness, and
nausea. Advanced stages may cause collapse, unconsciousness, coma
and possible death due to respiratory failure. Ingestion of large
amounts may cause CNS depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May cause respiratory tract irritation. Aspiration may lead
to pulmonary edema. Vapors may cause dizziness or suffocation. May
cause burning sensation in the chest.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those
of acute inhalation and ingestion. Prolonged or repeated skin
contact may cause defatting and dermatitis. Chronic exposure may
cause reproductive disorders and teratogenic effects.
Section 4 - First Aid Measures
|
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Will burn if involved in a fire. Flammable Liquid.
Can release vapors that form explosive mixtures at temperatures
above the flashpoint. Use water spray to keep fire-exposed
containers cool. Containers may explode in the heat of a fire. Vapors
are heavier than air and may travel to a source of ignition and flash
back. Vapors can spread along the ground and collect in low or
confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. In case of fire, use water, dry chemical,
chemical foam, or alcohol-resistant foam. Use water spray to cool
fire-exposed containers. Water may be ineffective. Do NOT use
straight streams of water.
Flash Point: 51 deg C ( 123.80 deg F)
Autoignition Temperature: 380 deg C ( 716.00 deg F)
Explosion Limits, Lower:1.70 vol %
Upper: 10.10 vol %
NFPA Rating:
(estimated) Health: 1; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation. A
vapor suppressing foam may be used to reduce vapors.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Avoid
contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Keep
container tightly closed. Keep away from heat, sparks and flame. Do
not pressurize, cut, weld, braze, solder, drill, grind, or expose
empty containers to heat, sparks or open flames. Use only with
adequate ventilation. Avoid breathing vapor or mist.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a cool, dry, well-ventilated area away from
incompatible substances. Flammables-area. Store protected from light
and air. Containers should be dated when opened and tested
periodically for the presence of peroxides. Should crystals form in a
peroxidizable liquid, peroxidation may have occurred and the product
should be considered extremely dangerous. In this instance, the
container should only be opened remotely by professionals. All
peroxidizable substances should be stored away from heat and light
and be protected from ignition sources.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility
and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible
exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
2-Ethoxyethyl acetate
|
5 ppm TWA; Skin - potential significant contribution to overall exposure by the cutaneous r oute
|
0.5 ppm TWA; 2.7 mg/m3 TWA 500 ppm IDLH
|
100 ppm TWA; 540 mg/m3 TWA
|
Water
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
2-Ethoxyethyl acetate:
100 ppm TWA; 540 mg/m3 TWA
Water:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: clear, colorless
Odor: ester-like
pH: Not available.
Vapor Pressure: 2.34 mm Hg @ 25 deg C
Vapor Density: 4.72 (Air=1)
Evaporation Rate:0.2
Viscosity: 1.32 cP 20 deg C
Boiling Point: 156 deg C @ 760 mm Hg
Freezing/Melting Point:-61 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:.9750g/cm3
Molecular Formula:C6H12O3
Molecular Weight:132.16
Section 10 - Stability and Reactivity
|
Chemical Stability:
Under normal storage conditions, peroxidizable compounds can form
and accumulate peroxides which may explode when subjected to heat or
shock. This material is most hazardous when peroxide levels are
concentrated by distillation or evaporation.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to flame, prolonged
exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, coatings, nitrates, plastics,
rubber.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 111-15-9:
KK8225000
CAS# 7732-18-5:
ZC0110000
LD50/LC50:
CAS# 111-15-9:
Dermal, guinea pig:
LD50 = >19460 mg/kg;
Draize test,
rabbit, eye: 40 mg Moderate;
Inhalation, rabbit: LC50 = >2000
ppm/4H;
Inhalation, rat: LC50 =
12100 mg/m3/8H;
Oral, rabbit: LD50
= 1950 mg/kg;
Oral, rat: LD50 =
2700 mg/kg;
Skin, rabbit: LD50 =
10500 uL/kg;
.
CAS# 7732-18-5:
Oral, rat:
LD50 = >90 mL/kg;
.
Carcinogenicity:
CAS# 111-15-9:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7732-18-5:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
No information found
Reproductive Effects:
In experiments with laboratory animals, EGEEA has caused
developmental abnormalities in the musculoskeletal,
respiratory, cardiovascular, and urogenital systems.
Paternal effects on the reproductive system and increases
in the post-implantation mortality rate have also been
observed. There have been no reports of adverse human
experience attributed to EGEEA.
Mutagenicity:
No information found
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 42.2 mg/L; 96 Hr.; Flow-through,
25.4-27.4 degrees C, pH6.9-7.7Fish: Goldfish: LC50 = 160.0 mg/L;
24 Hr.; Unspecified
No data available.
Environmental:
Volatilization of ethylene glycol monoethyl ether acetate may occur
from moist soil surfaces given an estimated Henry's Law constant of
1.8X10-6 atm-cu m/mole, calculated from experimental values for vapor
pressure and water solubility. Volatilization from dry soil surfaces
is expected based on a measured vapor pressure of 2.34 mm Hg, from
experimentally-derived coefficients. The dominant degradation process
for ethylene glycol monoethyl ether acetate in soil is expected to be
biodegradation.
Physical:
ATMOSPHERIC FATE: According to a model of gas/particle partitioning
of semivolatile organic compounds in the atmosphere, ethylene glycol
monoethyl ether acetate, which has a measured vapor pressure of 2.34
mm Hg at 25 deg C, from experimentally-derived coefficients, will
exist solely as a vapor in the ambient atmosphere. Vapor-phase
ethylene glycol monoethyl ether acetate is degraded in the
atmosphere by reaction with photochemically-produced hydroxyl
radicals; the half-life for this reaction in air is estimated to be
about 1.2 day.
Other:
The Koc of ethylene glycol monoethyl ether acetate is estimated as
approximately 5, using a measured water solubility of 229,000 mg/l
at 20 deg C and a regression-derived equation. According to a
recommended classification scheme, this estimated Koc value suggests
that ethylene glycol monoethyl ether acetate has very high mobility
in soil.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
ETHYLENE GLYCOL MONOETHYL ETHER ACETATE |
No information available. |
Hazard Class: |
3 |
|
UN Number: |
UN1172 |
|
Packing Group: |
III |
|
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 111-15-9 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 111-15-9: Section 5, 1 % de minimus concentration
TSCA Significant New Use Rule
CAS# 111-15-9: This product is for research and development use only.
It is subject to a SNUR which has specific requirements and restrictions.
The specific citation for this product is 4040 CFR 721.10001.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 111-15-9: immediate, delayed, fire.
Section 313
This material contains
2-Ethoxyethyl acetate (listed as Glycol ethers), 99.0%, (CAS#
111-15-9) which is subject to the reporting requirements of Section
313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 111-15-9 (listed as Glycol ethers (except for EGBE)) is listed as
a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 111-15-9 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains 2-Ethoxyethyl acetate, a chemical
known to the state of California to cause male reproductive
toxicity.
WARNING: This product contains 2-Ethoxyethyl acetate, a chemical
known to the state of California to cause developmental reproductive
toxicity.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 10 Flammable.
R 20/21/22 Harmful by inhalation, in contact with skin and if
swallowed.
R 60 May impair fertility.
R 61 May cause harm to the unborn child.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S 33 Take precautionary measures against static discharges.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 53 Avoid exposure - obtain special instructions before use.
S 9 Keep container in a well-ventilated place.
WGK (Water Danger/Protection)
CAS# 111-15-9: 1
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 111-15-9 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B, D2A.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 111-15-9 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 6/07/1999
Revision #5 Date: 11/20/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
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or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.