Material Safety Data Sheet
2,3-Butanedione, 99%
ACC# 03275
Section 1 - Chemical Product and Company Identification |
MSDS Name: 2,3-Butanedione, 99%
Catalog Numbers:
AC107650000, AC107650050, AC107651000, AC107655000
Synonyms:
Diacetyl; 2,3-Diketobutane; Dimethyl diketone; Dimethylglyoxal;
Biacetyl.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
431-03-8 |
2,3-Butanedione |
99 | 207-069-8 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: yellow to green liquid. Flash Point: 6 deg C.
Warning! Flammable liquid and
vapor. Causes eye, skin, and respiratory tract
irritation. Harmful if inhaled or swallowed. May cause central
nervous system depression. May cause lung damage. Marine pollutant.
Target Organs: Lungs, respiratory system, eyes,
skin.
Potential Health Effects
Eye:
Causes eye irritation. Causes redness and pain. May cause
chemical conjunctivitis and corneal damage.
Vision may become blurred.
Skin:
Causes moderate skin irritation. Causes redness and pain. May be
harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. Ingestion of large amounts may cause
CNS depression.
Inhalation:
Causes respiratory tract irritation. May cause lung damage. Vapors
may cause dizziness or suffocation. Harmful if inhaled. Inhalation of
vapors may cause drowsiness and dizziness.
High exposure to butanedione may cause headache, drowsiness, lack of
coordination and seizures. May cause a feeling of tightness in the
chest.
Chronic:
Chronic exposure may cause lung damage.
Repeated exposure may damage the red blood cells causing
anemia.2,3-Butanedione has been linked to bronchiolitis obliterans,
a disease characterized by inflammation and scarring in the smallest
airways of the lungs, which leads to severe and disabling shortness
of
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
diately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by
thermal decomposition or combustion. Containers may explode in the
heat of a fire. Flammable liquid and vapor. Vapors are heavier than
air and may travel to a source of ignition and flash back. Vapors
can spread along the ground and collect in low or confined areas.
Hazardous polymerization may occur under fire conditions.
Extinguishing Media:
Water may be ineffective. Water may spread fire. If water is the
only media available, use in flooding amounts. Do NOT use straight
streams of water. Use water fog, dry chemical, carbon dioxide or
alcohol type foam.
Flash Point: 6 deg C ( 42.80 deg F)
Autoignition Temperature: 365 deg C ( 689.00 deg F)
Explosion Limits, Lower:2.4%
Upper: 13.0%
NFPA Rating:
(estimated) Health: 2; Flammability: 3; Instability: 1
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. A vapor suppressing foam
may be used to reduce vapors.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Avoid
contact with eyes, skin, and clothing. Do not breathe dust, mist, or
vapor. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or
open flames. Keep away from heat, sparks and flame. Use only with
adequate ventilation or respiratory protection.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Refrigerator/flammables.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use process enclosure,
local exhaust ventilation, or other engineering controls to control
airborne levels.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
2,3-Butanedione
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
2,3-Butanedione:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: yellow to green
Odor: strong rancid - chlorine-like - butter-like
pH: Not available.
Vapor Pressure: 39 mm Hg @ 20 deg C
Vapor Density: 3 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 88 deg C @ 760 mm Hg
Freezing/Melting Point:-4 deg C
Decomposition Temperature:> 110 deg C
Solubility: Soluble.
Specific Gravity/Density:.9850
Molecular Formula:C4H6O2
Molecular Weight:86.09
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures. Material is heat
sensitive and may decompose at elevated temperatures.
Conditions to Avoid:
Light, ignition sources, excess heat.
Incompatibilities with Other Materials:
Metals, oxidizing agents, reducing agents, acids, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
|
RTECS#:
CAS# 431-03-8:
EK2625000
LD50/LC50:
CAS# 431-03-8:
Draize test,
rabbit, skin: 500 mg/24H Moderate;
Oral, rat: LD50 = 1580 mg/kg;
Oral, rat: LD50 = 3000 mg/kg;
Skin, rabbit: LD50 = >5 gm/kg;
.
Carcinogenicity:
CAS# 431-03-8:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
2,3-Butanedione has been associated with lung disease,
bronchiolitis obliterans, in workers at a
microwave-popcorn plant. Lung damage was so severe a
double lung transplant is needed in one of those afflicted.
Teratogenicity:
No information found
Reproductive Effects:
No information found
Mutagenicity:
Mutagenic effects have occurred in experimental animals.
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
No information available.
Environmental:
Biodegradable.
Physical:
No information available.
Other:
Marine pollutant.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
BUTANEDIONE |
FLAMMABLE LIQUID, TOXIC, N.O.S. (Butanedione) |
Hazard Class: |
3 |
3 |
UN Number: |
UN2346 |
UN1992 |
Packing Group: |
II |
II |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 431-03-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 431-03-8: immediate, fire.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 431-03-8 can be found on the
following state right to know lists: New Jersey, Pennsylvania,
Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN F
Risk Phrases:
R 11 Highly flammable.
R 20/22 Harmful by inhalation and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 33 Take precautionary measures against static discharges.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
WGK (Water Danger/Protection)
CAS# 431-03-8: 1
Canada - DSL/NDSL
CAS# 431-03-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 431-03-8 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 1/23/1998
Revision #8 Date: 3/16/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.