Material Safety Data Sheet
Bromobenzene
ACC# 03420
Section 1 - Chemical Product and Company Identification |
MSDS Name: Bromobenzene
Catalog Numbers:
AC106680000, AC106680010, AC106682500, B253-1
Synonyms:
Monobromobenzene; Phenyl bromide; Bromobenzol.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
108-86-1 |
Bromobenzene |
99 | 203-623-8 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 51 deg C.
Warning! Flammable liquid and
vapor. May be absorbed through intact skin. Causes
skin irritation. May cause eye and respiratory tract irritation. May
cause liver damage. Marine pollutant.
Target Organs: Liver, respiratory system, skin.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful
amounts. If absorbed, may cause liver injury.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May be harmful if swallowed.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May cause respiratory tract irritation. May cause narcotic
effects in high concentration. May cause liver abnormalities. Vapors
may cause dizziness or suffocation. May cause blood changes.
Chronic:
Chronic exposure may cause liver damage.
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. This chemical poses an explosion hazard. Flammable
liquid and vapor. Vapors are heavier than air and may travel to a
source of ignition and flash back. Vapors can spread along the
ground and collect in low or confined areas.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers.
Flash Point: 51 deg C ( 123.80 deg F)
Autoignition Temperature: 566 deg C ( 1,050.80 deg F)
Explosion Limits, Lower: .5%
Upper: 2.5%
NFPA Rating:
(estimated) Health: 2; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and
explosion proof equipment. Avoid contact with eyes, skin, and
clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Keep container tightly closed. Keep
away from heat, sparks and flame. Do not pressurize, cut, weld,
braze, solder, drill, grind, or expose empty containers to heat,
sparks or open flames. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low. Ventilation fans
and other electrical service must be non-sparking and have an
explosion-proof design.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Bromobenzene
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Bromobenzene:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: colorless
Odor: aromatic odor
pH: Not available.
Vapor Pressure: 3.3 mm Hg @ 20 deg C
Vapor Density: 5.41 (air=1)
Evaporation Rate:Not available.
Viscosity: 1.124 cP 20 deg C
Boiling Point: 155 deg C
Freezing/Melting Point:-31 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:1.49
Molecular Formula:C6H5Br
Molecular Weight:157.01
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable.
Conditions to Avoid:
Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 108-86-1:
CY9000000
LD50/LC50:
CAS# 108-86-1:
Inhalation, mouse:
LC50 = 21 gm/m3/2H;
Inhalation,
rat: LC50 = 20411 mg/m3;
Oral,
mouse: LD50 = 2700 mg/kg;
Oral,
rabbit: LD50 = 3300 mg/kg;
Oral,
rat: LD50 = 2383 mg/kg;
.
Carcinogenicity:
CAS# 108-86-1:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
No information found
Reproductive Effects:
No information found
Mutagenicity:
DNA repair(Escherichia coli)= 250 mg/LMicronucleus
test(Intraperitoneal,mouse) = 125 mg/kg/24H
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 9.46 mg/L; 30 minutes;
Microtox test; 15 degrees C
No data available.
Environmental:
Bromobenzene is not biodegraded in screening studies using an
activated sludge as inoculum; 0% degradation was reported after four
weeks. In water, bromobenzene may adsorb to sediment or particulate
matter based on its estimated Koc value of 268. This compound will
volatilize from water surfaces given its experimental Henry's Law
constant. Estimated half-lives for a model river and model lake are 4
hours and 5 days, respectively. Bioconcentration in aquatic organisms
should be low to moderate.
Physical:
If released to the the atmosphere, bromobenzene will exist in the
vapor phase in the ambient atmosphere, based on a measured vapor
pressure of 4.18 mm Hg at 25 deg C. Vapor-phase bromobenzene is
degraded in the atmosphere by reaction with photochemically-produced
hydroxyl radicals with a half-life of about 21 days. An estimated Koc
value of 268 suggests that bromobenzene will have moderate mobility
in soil. Volatilizaton from moist soil surfaces should occur.
Other:
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
BROMOBENZENE |
Bromobenzene |
Hazard Class: |
3 |
3 |
UN Number: |
UN2514 |
UN2514 |
Packing Group: |
III |
III |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 108-86-1 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-86-1: Effective 6/1/87, Sunset 12/19/95
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 108-86-1: immediate, delayed, fire.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 108-86-1 can be found on the
following state right to know lists: New Jersey, Pennsylvania,
Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI N
Risk Phrases:
R 10 Flammable.
R 38 Irritating to skin.
R 51/53 Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
Safety Phrases:
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.
WGK (Water Danger/Protection)
CAS# 108-86-1: 2
Canada - DSL/NDSL
CAS# 108-86-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B3, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
Section 16 - Additional Information
|
MSDS Creation Date: 5/20/1999
Revision #4 Date: 2/18/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.