Material Safety Data Sheet
1-Bromo-3-nitrobenzene, 99%
ACC# 05677
Section 1 - Chemical Product and Company Identification |
MSDS Name: 1-Bromo-3-nitrobenzene, 99%
Catalog Numbers:
AC160390000, AC160390250, AC160391000
Synonyms:
3-Bromonitrobenzene; 3-Nitrobromobenzene;
m-Bromonitrobenzene.m-Nitrobromobenzene; Benzene, 1-bromo-3-nitro-
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
585-79-5 |
1-Bromo-3-nitrobenzene |
99 | 209-563-9 |
Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: yellow to tan crystals.
Warning! Can decompose violently at elevated
temperatures. Harmful if swallowed, inhaled, or absorbed through the
skin. Causes eye, skin, and respiratory tract irritation. May cause
methemoglobinemia. Heat sensitive.
Target Organs: Blood.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful
amounts.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. The toxicological properties of this
substance have not been fully investigated. Effects may be delayed 2
to 4 hours. May form methemoglobin which in sufficient concentration
causes cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood).
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation. The
toxicological properties of this substance have not been fully
investigated. Can produce delayed pulmonary edema.
Chronic:
Prolonged exposure may cause anemia and methemoglobinemia,
characterized by dizziness, drowsiness, headache, breath shortness,
cyanosis (bluish skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown colored blood. Effects may be
delayed.
Section 4 - First Aid Measures
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Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively. Effects may be delayed. For
methemoglobinemia, administer oxygen alone or with Methylene Blue
depending on the methemoglobin concentration in the blood.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Exposure to heat may promote violent decomposition.
During a fire, irritating and highly toxic gases may be generated by
thermal decomposition or combustion. This material in sufficient
quantity and reduced particle size is capable of creating a dust
explosion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: > 112 deg C (> 233.60 deg F)
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 1; Instability: 2
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Minimize dust generation and accumulation. Avoid
contact with eyes, skin, and clothing. Keep container tightly closed.
Do not ingest or inhale. Use only with adequate ventilation. Keep
away from heat and flame.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low. Ventilation fans
and other electrical service must be non-sparking and have an
explosion-proof design.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
1-Bromo-3-nitrobenzene
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
1-Bromo-3-nitrobenzene:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
|
Physical State: Crystals
Appearance: yellow to tan
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 256 deg C @ 760 mm Hg
Freezing/Melting Point:51-54 deg C
Decomposition Temperature:Not available.
Solubility: insoluble
Specific Gravity/Density:1.700 g/cm3
Molecular Formula:C6H4BrNO2
Molecular Weight:202.01
Section 10 - Stability and Reactivity
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Chemical Stability:
Unstable at 56°C (132°F). Forbidden for transport in USA and Canada.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 585-79-5:
CY9040500
LD50/LC50:
Not available.
CAS# 98-95-3 (Nitrobenzene) Inhalation, rat: LC50 = 556 ppm/4H. Mean
adult lethal oral dose is estimated at 1-5 grams.
Carcinogenicity:
CAS# 585-79-5:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
Mutation in Microorganisms: Salmonella typhimurium = 500
ug/plate.
Neurotoxicity:
No information available.
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 3.59-4.96 mg/L; 5,15,30
min; Microtox test at 15C
Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
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US DOT |
Canada TDG |
Shipping Name: |
Forbidden By DOT |
Forbidden |
Hazard Class: |
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UN Number: |
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Packing Group: |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 585-79-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 585-79-5 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin and if
swallowed.
R 33 Danger of cumulative effects.
Safety Phrases:
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 28A After contact with skin, wash immediately with plenty of water
.
WGK (Water Danger/Protection)
CAS# 585-79-5: No information available.
Canada - DSL/NDSL
CAS# 585-79-5 is listed on Canada's NDSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2B, F.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 585-79-5 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
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MSDS Creation Date: 6/01/1999
Revision #4 Date: 3/16/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.