Material Safety Data Sheet
Section 1 - Chemical Product and Company Identification
MSDS Name: Cyclohexanone
AC111190000, AC111190250, AC111190251, AC406095000, 11119-0010, 11119-0025,
C550-4, NC9335342, NC9449331, NC9619559, O2109-1, O2109-4, O2109-4LC,
O2109FB-115, O2109FB-19, O2109FB-200, O2109FB-50, O2109POP-19, O2109POP-200,
O2109POP-50, O2109POPB-20, O2109POPB-50, O2109RB-200, O2109RB-50,
O2109RS-19, O2109SS-115, O2109SS-19, O2109SS-200, O2109SS-28, O2109SS-50
Ketohexamethylene; Pimelic ketone.
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|| 98+ ||203-631-1
Section 3 - Hazards Identification
Appearance: APHA: 10 max liquid. Flash Point: 46 deg C.
Warning! Possible cancer hazard. May cause cancer
based on animal data. Flammable liquid and vapor.
Harmful if inhaled. Causes eye and skin irritation. May cause
respiratory tract irritation. May cause central nervous system
Target Organs: Blood, kidneys, central nervous
system, liver, respiratory system, eyes, skin.
Potential Health Effects
Causes eye irritation.
Undiluted cyclohexanone placed in the eyes of rabbits caused marked
irritation and some corneal injury.
Causes skin irritation. May be harmful if absorbed through the skin.
Cyclohexanone was not a sensitizer in the guinea pig maximization
test and the mouse ear swelling test. There has been one case report
of sensitization to cyclohexanone itself in a patient using a PVC
adhesive composed of 100% cyclohexanone; patch testing confirmed the
May cause irritation of the digestive tract. May be harmful if
swallowed. May cause central nervous system effects.
Harmful if inhaled. May cause respiratory tract irritation. May
cause central nervous system effects.
Cyclohexanone has caused damage to the liver and kidneys in rabbits
exposed by inhalation to an airborne concentration of 190 ppm.
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause dermatitis. May cause
liver and kidney damage. Adverse reproductive effects have been
reported in animals. Laboratory experiments have resulted in
mutagenic effects. Chronic exposure may cause blood effects.
Section 4 - First Aid Measures
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Get medical aid. Immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Do not induce vomiting. Get medical aid.
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do not use
mouth-to-mouth resuscitation if victim ingested or inhaled the
substance; induce artificial respiration with the aid of a pocket
mask equipped with a one-way valve or other proper respiratory
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn
if involved in a fire. Containers may explode in the heat of a fire.
Flammable liquid and vapor.
Use water spray to cool fire-exposed containers. Use foam, dry
chemical, or carbon dioxide. Water may be ineffective.
Flash Point: 46 deg C ( 114.80 deg F)
Autoignition Temperature: 520 deg C ( 968.00 deg F)
Explosion Limits, Lower:1.10 vol %
Upper: 8.10 vol %
(estimated) Health: 2; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Wear a self contained breathing
apparatus and appropriate personal protection. (See Exposure
Controls, Personal Protection section). Remove all sources of
ignition. Use a spark-proof tool. Do not let this chemical enter the
Section 7 - Handling and Storage
Use spark-proof tools and explosion proof equipment. Do not get in
eyes, on skin, or on clothing. Take precautionary measures against
static discharges. Keep away from heat, sparks and flame. Do not
ingest or inhale. Use only in a chemical fume hood.
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Flammables-area.
Section 8 - Exposure Controls, Personal Protection
Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility
and a safety shower. Use only under a chemical fume hood.
||OSHA - Final PELs|
20 ppm TWA; 50 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute
25 ppm TWA; 100 mg/m3 TWA 700 ppm IDLH
50 ppm TWA; 200 mg/m3 TWA
OSHA Vacated PELs:
25 ppm TWA; 100 mg/m3 TWA
Personal Protective Equipment
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless - APHA: 10 max
Odor: none reported
pH: Not applicable.
Vapor Pressure: 4.5 mbar @ 20 deg C
Vapor Density: 3.4 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 155 deg C @ 760 mmHg
Freezing/Melting Point:-47 deg C
Decomposition Temperature:Not available.
Solubility: Slightly soluble.
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Reducing agents, plastics.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
rabbit, eye: 20 mg Severe;
test, rabbit, eye: 250 ug/24H Severe;
Inhalation, mouse: LC50 = 2375
Inhalation, rat: LC50 = 8000
Inhalation, rat: LC50 =
Oral, mouse: LD50 =
Oral, rat: LD50 = 1620
Oral, rat: LD50 = 1800
Skin, rabbit: LD50 = 1
- ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans
- California: Not listed.
- NTP: Not listed.
- IARC: Not listed.
ACGIH has labeled this substance as a confirmed animal
Teratogenic effects have occurred in experimental animals.
Adverse reproductive effects have occurred in experimental
Mutation in microorganisms:See actual entry in RTECS for
No information found
Section 12 - Ecological Information
Fish: Rainbow trout: LC50 = 90.0 mg/L; 96 Hr.; 320.0 mg/L
CaCO3Fish: Rainbow trout: LC50 = 44.0 mg/L; 96 Hr.; 20.0 mg/L
CaCO3Fish: Fathead Minnow: LC50 = 527.0 mg/L; 96 Hr.;
Flow-through, 24-26 degrees C,pH7.5Water flea Daphnia: EC50 =
820.0 mg/L; 48 Hr.; UnspecifiedAlgae: EC50 = 20.0 mg/L; 96 Hr.;
UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 18.7
mg/L; 5 minutes; Microtox Test
No data available.
This chemical is expected to rapidly volatilize based on its low
melting and boiling point. Cyclohexanone is estimated to be highly
mobile in soil. In view of its moderate vapor pressure and low
adsorption to soil, it would be expected to volatilize from surface
soil. Although data are lacking, it may also undergo direct
photolysis on the soil surface. Cyclohexanone is readily
biodegradable according to aerobic screening tests and therefore
would be expected to biodegrade in soil.
No information found.
The bioconcentration factor (BCF) for cyclohexanone can be estimated
to be 2.4 based on the log Kow of 0.81 and a recommended regression
equation. This BCF indicates that cyclohexanone will not
bioconcentrate in aquatic organisms.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
CAS# 108-94-1: waste
number U057 (Ignitable waste).
Section 14 - Transport Information
Section 15 - Regulatory Information
CAS# 108-94-1 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-94-1: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-94-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 108-94-1: immediate, delayed, fire.
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product
are considered highly hazardous by OSHA.
CAS# 108-94-1 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European Labeling in Accordance with EC Directives
R 10 Flammable.
R 20 Harmful by inhalation.
S 25 Avoid contact with eyes.
WGK (Water Danger/Protection)
CAS# 108-94-1: 1
Canada - DSL/NDSL
CAS# 108-94-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B3, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 108-94-1 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
MSDS Creation Date: 6/01/1999
Revision #9 Date: 7/24/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.