Material Safety Data Sheet
Ethanolamine
ACC# 08710
Section 1 - Chemical Product and Company Identification |
MSDS Name: Ethanolamine
Catalog Numbers:
AC149580000, AC149580010, AC149580025, AC149580200, AC149580250,
AC409530000, AC409530250, AC409535000, EK1364603, M251-1, M251-4
Synonyms:
2-Aminoethanol; Monoethanolamine.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
141-43-5 |
Ethanolamine |
99 | 205-483-3 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: clear viscous liquid. Flash Point: 85 deg C.
Danger! Causes burns by all exposure routes.
Harmful if absorbed through skin or if inhaled.
Combustible liquid and vapor. May be harmful if
swallowed. May cause central nervous system depression. May cause
liver damage. May cause kidney damage.
Target Organs: Kidneys, central nervous system,
liver, lungs, eyes, skin, mucous membranes.
Potential Health Effects
Eye:
Causes eye burns. May cause chemical conjunctivitis and corneal
damage.
Skin:
Causes moderate skin irritation. Harmful if absorbed through the
skin. Causes skin burns. May cause dermatitis. May cause cyanosis of
the extremities. May cause skin rash (in milder cases), and cold and
clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. May
cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Causes gastrointestinal tract burns. May cause perforation
of the digestive tract. May cause systemic effects.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Causes chemical burns to the respiratory tract. Aspiration
may lead to pulmonary edema. May cause systemic effects. Inhalation
at high concentrations may cause CNS depression and asphixiation.
Chronic:
May cause liver and kidney damage. Effects may be delayed.
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
diately. Do NOT allow victim to rub eyes or keep eyes closed. Extensiv
e irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Vapors mixed with air can
explode when ignited. Vapors may be heavier than air. They can
spread along the ground and collect in low or confined areas.
Containers may explode when heated. Combustible liquid and vapor.
Extinguishing Media:
Use water spray, dry chemical, "alcohol resistant" foam, or carbon
dioxide.
Flash Point: 85 deg C ( 185.00 deg F)
Autoignition Temperature: 410 deg C ( 770.00 deg F)
Explosion Limits, Lower:3.0% @140°C
Upper: 23.5% @140°C
NFPA Rating:
(estimated) Health: 3; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Do not get in eyes, on skin,
or on clothing. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Keep container tightly closed.
Discard contaminated shoes. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or
open flames. Keep away from heat and flame. Do not breathe vapor or
mist.
Storage:
Keep away from sources of ignition. Keep container closed when not
in use. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Isolate from
oxidizing materials and acids.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Ethanolamine
|
3 ppm TWA; 6 ppm STEL
|
3 ppm TWA; 8 mg/m3 TWA 30 ppm IDLH
|
3 ppm TWA; 6 mg/m3 TWA
|
OSHA Vacated PELs:
Ethanolamine:
3 ppm TWA; 8 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use. Follow the OSHA
respirator regulations found in 29 CFR 1910.134 or
European Standard EN 149. Use a NIOSH/MSHA or
European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or
other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: clear viscous
Odor: ammonia-like - fish-like - objectionable
pH: 12.1 @ 1N
Vapor Pressure: .48 mm Hg @ 20 deg C
Vapor Density: 2.1(Air = 1)
Evaporation Rate:>1 (butyl acetate=1)
Viscosity: 24 cP 20 deg C
Boiling Point: 170 deg C
Freezing/Melting Point:10 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.018 @ 20°C
Molecular Formula:C2H7NO
Molecular Weight:61.0551
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures. Absorbs carbon
dioxide from the air.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Reacts violently with acetic acid, acetic anhydride, acrolein,
acrylic acid, acrylonitrile, cellulose, chlorosulfonic acid,
epichlorohydrin, HCl, HF, mesityl oxide, HNO3, oleum, H2SO4,
b-propiolactone, vinyl acetate.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 141-43-5:
KJ5775000
LD50/LC50:
CAS# 141-43-5:
Draize test,
rabbit, eye: 250 ug Severe;
Oral,
mouse: LD50 = 700 mg/kg;
Oral,
rabbit: LD50 = 1 gm/kg;
Oral, rat:
LD50 = 1720 mg/kg;
Skin, rabbit:
LD50 = 1 mL/kg;
.
Carcinogenicity:
CAS# 141-43-5:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
No information found
Reproductive Effects:
TDLo (Oral, rat) = 500 mg/kg; Effects on Embryo or Fetus -
fetotoxicity (except death, e.g., stunted fetus), fetal
death, Specific Developmental Abnormalities -
musculoskeletal system;TDLo(Oral, rat) = 500 mg/kg;
Reproductive - Specific Developmental Abnormalities -
urogenital system.
Mutagenicity:
Cytogenetic analysis(Human Lymphocyte) =100 umol/LSister
chromatid exchange (Human Lymphocyte) =1 mmol/L
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
Fish: Goldfish: LC50 = 170.0 mg/L; 96 Hr.; UnspecifiedBacteria:
Phytobacterium phosphoreum: EC50 = 13.7 mg/L; 30 minutes; Microtox
test
No data available.
Environmental:
If released to soil, 2-aminoethanol (MEA) is expected to biodegrade
fairly rapidly following acclimation (half-life on the order of days
to weeks). MEA is expected to leach in soil. Volatilization from
soil surfaces is not expected to be an important fate process. If
released to water, 2-aminoethanol should undergo biodegradation. The
half-life of this compound is expected to range from a few days to a
few weeks depending, in large part, on the degree of acclimation of
the system.
Physical:
Based on a vapor pressure of 0.26 mm Hg at 25 deg C, 2-aminoethanol
(MEA) is expected to exist almost entirely in the vapor phase in the
atmosphere. The dominant removal mechanism is expected to be
reaction with photochemically generated hydroxyl radicals (half-life
4 hours). The complete solubility of MEA in water suggests that this
compound may also be removed from the atmosphere in precipitation.
Other:
A bioconcentration factor (BCF) of <1 was estimated for
2-aminoethanol (MEA) based on a log Kow of -1.31. This BCF value and
complete solubility of MEA in water suggest that this compound does
not bioconcentrate significantly in aquatic organisms.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
ETHANOLAMINE |
ETHANOLAMINE |
Hazard Class: |
8 |
8 |
UN Number: |
UN2491 |
UN2491 |
Packing Group: |
III |
III |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 141-43-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 141-43-5: immediate, fire.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 141-43-5 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with skin and if
swallowed.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 141-43-5: 1
Canada - DSL/NDSL
CAS# 141-43-5 is listed on Canada's DSL List.
Canada - WHMIS
not available.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 141-43-5 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 6/24/1999
Revision #5 Date: 4/29/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.