Material Safety Data Sheet
Glutaraldehyde Solutions
ACC# 10421
Section 1 - Chemical Product and Company Identification |
MSDS Name: Glutaraldehyde Solutions
Catalog Numbers:
AC410960000, AC410960030, AC410965000, BP2547-1, G151-1, NC9228868,
NC9368586, NC9714828, NC9984657
Synonyms:
Glutaraldehyde; 1,5 -Pentanedial; Glutaral; Glutaric dialdehyde.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
111-30-8 |
Glutaraldehyde |
50 | 203-856-5 |
7732-18-5 |
Water |
50 | 231-791-2 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid.
Danger! Causes eye and skin burns. Causes
digestive and respiratory tract burns. May cause allergic
respiratory and skin reaction. Harmful if swallowed, inhaled, or
absorbed through the skin. Aspiration hazard if swallowed. Can enter
lungs and cause damage. Dangerous for the environment.
Target Organs: Central nervous system, lungs,
respiratory system, eyes, skin.
Potential Health Effects
Eye:
Causes eye irritation and burns. May cause permanent visual
impairment. May cause chemical conjunctivitis and corneal damage.
Skin:
May cause skin sensitization, an allergic reaction, which becomes
evident upon re-exposure to this material. May cause hives. Causes
skin irritation and burns. May cause staining of the hands (brownish
or tan).
Ingestion:
Harmful if swallowed. Causes gastrointestinal tract burns. May cause
central nervous system depression, characterized by excitement,
followed by headache, dizziness, drowsiness, and nausea. Advanced
stages may cause collapse, unconsciousness, coma and possible death
due to respiratory failure. Possible aspiration hazard. May cause
lung damage.
Inhalation:
Harmful if inhaled. Causes chemical burns to the respiratory tract.
May cause asthma and shortness of breath. May cause nausea,
dizziness, and headache.
Chronic:
Effects may be delayed. Repeated or prolonged exposure may cause
allergic reactions in sensitive individuals.
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
diately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately. Call a poison
control center. Do not give anything by mouth. Oral toxicity of
Glutaraldehyde increases with dilution. Drinking water following
ingestion of concentrated Glutaraldehyde solutions can enhance the
toxicity.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
If breathing has ceased apply artificial respiration using oxygen
and a suitable mechanical device such as a bag and a mask. As in any
fire, wear a self-contained breathing apparatus in pressure-demand,
MSHA/NIOSH (approved or equivalent), and full protective gear. During
a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 3; Flammability: 1; Instability: 1
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective
Equipment section. Absorb spill using an absorbent, non-combustible
material such as earth, sand, or vermiculite. Do not use combustible
materials such as sawdust. Provide ventilation.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Do not get in eyes, on skin, or on clothing. Use
only with adequate ventilation. Avoid breathing vapor.
Storage:
Keep container closed when not in use. Store in a cool, dry,
well-ventilated area away from incompatible substances. Refrigeration
has been recommended.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Glutaraldehyde
|
0.05 ppm Ceiling (activated and inactivated)
|
none listed
|
none listed
|
Water
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Glutaraldehyde:
No OSHA Vacated PELs are listed for this chemical.
Water:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: clear, colorless
Odor: sharp odor - fruity odor - medicinal odor
pH: 3.1 - 4.5
Vapor Pressure: 15 mm Hg @ 20 deg C
Vapor Density: 1.05 (air=1)
Evaporation Rate:0.93 (BuAc =1)
Viscosity: Not available.
Boiling Point: 101 deg C
Freezing/Melting Point:-21 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.13 g/cm3
Molecular Formula:C5H8O2
Molecular Weight:100.12
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Exposure to air, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, Note: [ Alkaline solutions of
glutaraldehyde (i.e., activated glutaraldehyde) react with alcohol,
ketones, amines, hydrazines and proteins.].
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
|
RTECS#:
CAS# 111-30-8:
MA2450000
CAS# 7732-18-5:
ZC0110000
LD50/LC50:
CAS# 111-30-8:
Draize test,
rabbit, eye: 1 mg Severe;
Draize
test, rabbit, eye: 250 ug/24H Severe;
Draize test, rabbit, skin: 2 mg/24H
Severe;
Inhalation, rat: LC50 = 480
mg/m3/4H;
Oral, mouse: LD50 = 100
mg/kg;
Oral, mouse: LD50 = 231
mg/kg;
Oral, rat: LD50 = 134
mg/kg;
Oral, rat: LD50 = 140
mg/kg;
Skin, rabbit: LD50 = 560
uL/kg;
Skin, rat: LD50 = >2500
mg/kg;
.
CAS# 7732-18-5:
Oral, rat:
LD50 = >90 mL/kg;
.
Carcinogenicity:
CAS# 111-30-8:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7732-18-5:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
See actual entry in RTECS for complete information.
Reproductive Effects:
TDLo - Lowest published toxic dose(Oral, rat) = 875 mg/kg;
Paternal Effects - testes, epididymis, sperm duct,
prostate, seminal vesicle, Cowper's gland, accessory
glands.TDLo - Lowest published toxic dose(Oral,rat) = 4370
mg/kg; Maternal Effects - uterus, cervix, vagina.
Mutagenicity:
Mutation in microorganisms(Salmonella typhimurium)=150
ug/plateMutation in microorganisms(Escherichia coli)=
62500ng/plate.
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 76.0 mg/L; 5 minutes;
Microtox test
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
TOXIC LIQUIDS, CORROSIVE, ORGANIC, N.O.S. |
TOXIC LIQUID ORGANIC NOS (GLUTARALDEHYDE) |
Hazard Class: |
6.1 |
6.1 |
UN Number: |
UN2927 |
UN2810 |
Packing Group: |
II |
III |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 111-30-8 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 111-30-8: immediate.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 111-30-8 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 7732-18-5 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T N
Risk Phrases:
R 23/25 Toxic by inhalation and if swallowed.
R 34 Causes burns.
R 42/43 May cause sensitization by inhalation and skin contact.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.
WGK (Water Danger/Protection)
CAS# 111-30-8: 2
CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
CAS# 111-30-8 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2A, D2B, E.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 111-30-8 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 6/07/1999
Revision #8 Date: 1/29/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.