Material Safety Data Sheet
Iodine

ACC# 11400
Section 1 - Chemical Product and Company Identification

MSDS Name: Iodine
Catalog Numbers: S75028, S750282, S75138, S75139, S93266, I35-100, I35-500, I37-100, I37-500, NC9271185, NC9272135
Synonyms:
None.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
7553-56-2 Iodine >99 231-442-4

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: black-violet solid.
Danger! Causes burns by all exposure routes. Harmful if swallowed, inhaled, or absorbed through the skin. May cause allergic skin reaction. At ordinary temperatures, iodine sublimes to a violet gas with a characteristic, irritating odor.
Target Organs: Respiratory system, eyes, thyroid, skin.


Potential Health Effects
Eye: Causes severe eye irritation. May cause eye burns. Vapors cause eye irritation.
Skin: Harmful if absorbed through the skin. May cause severe irritation and possible burns. Rare instances of allergic reactions to topical iodine solutions characterized by fever and generalized skin eruptions have lead to death. At least one death after topical application of a strong iodine tincture to one-third of the body has been recorded.
Ingestion: Harmful if swallowed. May cause burns to the digestive tract. Iodine is an easily oxidizable substance. Food that is present in the GI tract will oxidize iodine to iodide which is not corrosive to the GI tract.
Inhalation: Harmful if inhaled. Causes severe respiratory tract irritation. Extreme exposures could result in a build-up of fluid in the lungs (pulmonary edema) that might be fatal in severe cases. Readily sublimed having a violet vapor (Hawley's Condensed Chemical Dictionary). Inhalation of iodine vapor is intensely irritating to mucous membranes and adversely affects both the upper and lower portions of the pulmonary tract (Doc of TLV).
Chronic: Chronic exposure can lead to iodism characterized by headache, excess salivation, nasal discharge, conjunctivitis, laryngitis, bronchitis, stomatitis, enlarged submaxillary glands, and skin rashes. Chronic ingestion of iodides during pregnancy has resulted in fetal death, severe goiter, and cretinoid appearance of the newborn. Chronic exposure can affect thyroid function. Some references (e.g. Dreisbach's Handbook) say that iodine and iodine compounds are potent sensitizers and that repeated contact may cause sensitivity dermatitis, laryngeal edema, serum sickness with lymph node enlargement, and joint pain and swelling. Iodine in very small quantities is critical for proper function of the thyroid. If deficient, can cause goiter, an enlargement of the thyroid gland.

Section 4 - First Aid Measures


Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.
Ingestion: POISON material. If swallowed, get medical aid immediately. Only induce vomiting if directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible. Vapors may accumulate in confined spaces
Extinguishing Media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Storage: Store in a cool, dry place. Store in a tightly closed container.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Iodine 0.1 ppm Ceiling 2 ppm IDLH 0.1 ppm Ceiling; 1 mg/m3 Ceiling

OSHA Vacated PELs: Iodine: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: black-violet
Odor: iodine-like
pH: Not available.
Vapor Pressure: 0.3 mm Hg @ 20 deg C
Vapor Density: 8.8 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 184 deg C
Freezing/Melting Point:113 deg C
Decomposition Temperature:Sublimes
Solubility: 0.034 g/100 ml @ 25C
Specific Gravity/Density:4.93
Molecular Formula:I2
Molecular Weight:253.81

Section 10 - Stability and Reactivity


Chemical Stability: Stable. Substance is sublimable, able to go directly from solid to vapor.
Conditions to Avoid: Dust generation, excess heat.
Incompatibilities with Other Materials: Ammonia, acetylene, acetaldehyde, powdered aluminum, active metals, liquid chlorine, fluorine, carbides.
Hazardous Decomposition Products: Hydrogen iodide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 7553-56-2: NN1575000
LD50/LC50:
CAS# 7553-56-2:
     Oral, mouse: LD50 = 22 gm/kg;
     Oral, mouse: LD50 = 1000 mg/kg;
     Oral, rabbit: LD50 = 10 gm/kg;
     Oral, rat: LD50 = 14 gm/kg;
.
Oral LDLo human: 28 mg/kg (RTECS).
Carcinogenicity:
CAS# 7553-56-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: There are many reported cases of women taking iodine-containing drugs during pregnancy and having newborns with congenital goiter, a potentially life-threatening condition for the fetus or infant.
Reproductive Effects: Reproductive effects have been reported in animals.
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: CORROSIVE SOLIDS, TOXIC, N.O.S. CORROSIVE SOLID, TOXIC, N.O.S.*
Hazard Class: 8 8
UN Number: UN2923 UN2923
Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 7553-56-2 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 7553-56-2: immediate, delayed, fire.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 7553-56-2 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN N
Risk Phrases:

     R 20/21 Harmful by inhalation and in contact with skin.
     R 50 Very toxic to aquatic organisms.

Safety Phrases:

     S 23 Do not inhale gas/fumes/vapour/spray.
     S 25 Avoid contact with eyes.
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)

     CAS# 7553-56-2: 1
Canada - DSL/NDSL
     CAS# 7553-56-2 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 7553-56-2 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #11 Date: 8/22/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.