Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
123-30-8	4-Aminophenol	97.5	204-616-2

Section 3 - Hazards Identification

Appearance: beige crystalline powder.
Warning! Harmful if inhaled or swallowed. Possible risks of irreversible effects. Causes eye and skin irritation. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. May cause methemoglobinemia. May cause sensitization by skin contact.
Target Organs: Blood, kidneys, liver, respiratory system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May cause dermatitis. May be harmful if absorbed through the skin. May cause sensitization by skin contact.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Overexposure may cause methemoglobinemia.
Inhalation: Harmful if inhaled. May cause respiratory tract irritation. May cause methemoglobinemia.
Chronic: May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death. Adverse reproductive effects have been reported in animals. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause blood effects. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: > 189 deg C (> 372.20 deg F)
Autoignition Temperature: > 250 deg C (> 482.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 1

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment.

Section 7 - Handling and Storage

Handling: Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
4-Aminophenol	none listed	none listed	none listed

OSHA Vacated PELs: 4-Aminophenol: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties

Physical State: Crystalline powder
Appearance: white to cream - beige
Odor: amine-like - weak odor
pH: Not available.
Vapor Pressure: 0.4 hPa @ 110 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 284 deg C @ 760 mmHg
Freezing/Melting Point:187 - 191 deg C
Decomposition Temperature:> 284 deg C
Solubility: 1.5 g/100mL (20°C)
Specific Gravity/Density:Not available.
Molecular Formula:C6H7NO
Molecular Weight:109.13

Section 10 - Stability and Reactivity

Chemical Stability: Air sensitive. Light sensitive. May discolor on exposure to air and light.
Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air.
Incompatibilities with Other Materials: Strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates, bases.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

RTECS#:      
CAS# 123-30-8: SJ5075000
LD50/LC50:
CAS# 123-30-8:
     Draize test, rabbit, eye: 100 mg Mild;
     Draize test, rabbit, skin: 12500 ug/24H Mild;
     Inhalation, rat: LC50 = >5 mg/m3/1H;
     Oral, rabbit: LD50 = 10 gm/kg;
     Oral, rat: LD50 = 375 mg/kg;
     Skin, rabbit: LD50 = >10 gm/kg;
.

Carcinogenicity:
CAS# 123-30-8: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: Teratogenic effects have occurred in experimental animals.
Reproductive Effects: Adverse reproductive effects have occurred in experimental animals.
Mutagenicity: Mutagenic effects have occurred in humans.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Daphnia: Fathead Minnow: EC50=0.032 mg/l; ; cas#123-30-8Fish: Fathead Minnow: LC50 = 24 mg/L; 96 Hr.; Static Conditions, 22 degrees CFish: Goldfish: LC50 = 2 mg/L; 48 Hr.; Unspecified ConditionsBacteria: Phytobacterium phosphoreum: EC50 = 0.77-3.97 mg/L; 5,15,30 minutes; Microtox test No data available.
Environmental: No information available.
Physical: No information available.
Other: LC50=0.32 mg/l in Gammarus fasciatus and Dugesia tigrina; CAS#123-30-8: LC50=0.032 mg/l in Pimephales promelas and 3.2 mg/l in Helisoma trivolvis.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	AMINOPHENOLS	AMINOPHENOLS
Hazard Class:	6.1	6.1
UN Number:	UN2512	UN2512
Packing Group:	III	III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 123-30-8 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 123-30-8: immediate.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 123-30-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN N
Risk Phrases:
     R 20/22 Harmful by inhalation and if swallowed.
     R 50/53 Very toxic to aquatic organisms, may cause long-term
     adverse effects in the aquatic environment.
     R 68 Possible risk of irreversible effects.

Safety Phrases:
     S 36/37 Wear suitable protective clothing and gloves.
     S 60 This material and its container must be disposed of as hazardou
     s waste.
     S 28A After contact with skin, wash immediately with plenty of water
     .
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)
     CAS# 123-30-8: 2
Canada - DSL/NDSL
     CAS# 123-30-8 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1B, D2A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 123-30-8 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 6/16/1999
Revision #6 Date: 2/28/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.