Material Safety Data Sheet
Section 1 - Chemical Product and Company Identification
MSDS Name: m-Xylene
NC9517608, O5078-1, O5079-4
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|| 100 ||203-576-3
Hazard Symbols: XN
Risk Phrases: 10 20/21 38
Section 3 - Hazards Identification
Appearance: clear, colorless liquid. Flash Point: 25 deg C.
Flammable liquid and vapor.
May cause central nervous system depression. May cause liver and
kidney damage. Aspiration hazard if swallowed. Can enter lungs and
cause damage. Causes respiratory tract irritation.
Warning! Causes eye irritation. Prolonged or repeated
contact may dry the skin and cause irritation. May be harmful if
absorbed through skin or if inhaled. This substance has caused
adverse reproductive and fetal effects in animals.
Target Organs: Blood, kidneys, central nervous
system, liver, lungs, eyes, skin, mucous membranes.
Potential Health Effects
Causes severe eye irritation. Splashes of xylene in human eyes
generally cause transient superficial injury.
May be harmful if absorbed through the skin. Xylene contact causes
defatting of the skin with irritation, dryness, and cracking.
Blistering may occur, particularly if exposure to concentrated xylene
is prolonged and the exposed area of skin is occluded.
Aspiration hazard. May cause irritation of the digestive tract. May
cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and
possible death due to respiratory failure. May cause effects similar
to those of acute inhalation.
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Prolonged exposure may result in dizziness and general
weakness. Irritation may lead to chemical pneumonitis and pulmonary
edema. May cause liver and kidney damage. Causes irritation of
mucous membrane. Exposure may cause blood abnormalities. Odor is not
an adequate warning for overexposure to xylene.
Chronic exposure to xylene may cause defatting dermatitis,
reversible eye damage, dyspnea (labored breathing), confusion,
dizziness, apprehension, memory loss, headache, tremors, weakness,
anorexia, nausea, ringing in the ears, irritability, thirst, mild
changes in liver function, kidney impairment, anemia, and
hyperplasia, but not destruction, of the bone marrow.
Section 4 - First Aid Measures
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person.
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Flammable liquid and vapor. Vapors may form an
explosive mixture with air. Vapors are heavier than air and may
travel to a source of ignition and flash back. Vapors can spread
along the ground and collect in low or confined areas. This liquid
floats on water and may travel to a source of ignition and spread
fire. May accumulate static electricity.
Use water spray to cool fire-exposed containers. Water may be
ineffective. This material is lighter than water and insoluble in
water. The fire could easily be spread by the use of water in an
area where the water cannot be contained. Use water spray, dry
chemical, carbon dioxide, or appropriate foam.
Flash Point: 25 deg C ( 77.00 deg F)
Autoignition Temperature: 527 deg C ( 980.60 deg F)
Explosion Limits, Lower:1.1%
(estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Provide ventilation. A vapor suppressing foam may be used to reduce
vapors. Water spray may reduce vapor but may not prevent ignition in
closed spaces. U.S. regulations require reporting spills and releases
to soil, water and air in excess of reportable quantities. This
material creates a fire hazard because it floats on water. If
possible, try to contain floating material.
Section 7 - Handling and Storage
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind,
or expose empty containers to heat, sparks or open flames. Use only
with adequate ventilation. Keep away from heat, sparks and flame.
Avoid breathing vapor or mist.
Keep away from sources of ignition. Keep container closed when not
in use. Keep from contact with oxidizing materials. Store in a cool,
dry, well-ventilated area away from incompatible substances. Keep
away from strong acids.
Section 8 - Exposure Controls, Personal Protection
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
||OSHA - Final PELs|
|m-Xylene||100 ppm TWA; 150 ppm STEL
||100 ppm TWA; 435 mg/m3 TWA 900 ppm IDLH||none listed
OSHA Vacated PELs:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Wear chemical goggles.
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use
a NIOSH or European Standard EN 149 approved
respirator when necessary.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: aromatic odor
pH: Not applicable.
Vapor Pressure: 6.72 mm Hg @ 21 deg C
Vapor Density: 3.66 (air=1)
Evaporation Rate:0.7 (butyl acetate=1)
Viscosity: <32.6 SUS
Boiling Point: 139 deg C
Freezing/Melting Point:-48 deg C
Decomposition Temperature:Not available.
Specific Gravity/Density:0.86 (water=1)
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, acetic acid, nitric acid.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
CAS# 108-38-3: ZE2275000
Draize test, rabbit, eye: 5 mg/24H Severe;
Draize test, rabbit, skin: 20 mg/24H Moderate;
Oral, rat: LD50 =
Skin, rabbit: LD50 = 14100 uL/kg;
ACGIH: A4 - Not Classifiable as a Human Carcinogen
IARC: IARC Group 3 - not classifiable (listed as Xylenes (o-, m-, p- isomers)).
No information available.
No information available.
There is ample evidence that xylene produces embryotoxicity (reduced
body weight, retarded ossification, retarded kidney development,
increased extra rib) and fetotoxicity in mice and rats, but xylene
is not considered teratogenic.
No information available.
No information available.
Standard Draize Test: Administration into the eye (rabbit)
= 5 mg/24H (Severe). Standard Draize Test: Administrat
ion onto the skin (rabbit) = 500 mg (Moderate).
Section 12 - Ecological Information
Fish: Rainbow trout: LC50 = 13.5 mg/L; 96 Hr; Unspecified
Goldfish: LD50 = 13 mg/L; 24 Hr; Unspecified
LC50 = 46 mg/L; 1 Hr; Static bioassay
Acute and long-term toxicity to fish and invertebrates: LD50 for
goldfish is 13 mg/L/24 Hr.Cas#1330-20-7:LC50(96Hr.) rainbow trout =
8.05 mg/L, Static condition;LC50(96Hr.) fathead minnow = 16.1 mg/L,
flow-through conditions; LC50(96Hr.) bluegill = 16.1 mg/L,
flow-through;EC50 (48 Hr.) water flea = 3.82 mg/L, flow-through
conditions;EC50(24 Hr.) photobacterium phosphoreum = 0.0084 mg/L,
In air, xylenes degrade by reacting with photochemically produced
hydroxyl radicals. In soil it will volatilize and leach into
groundwater. Little bioconcentration is expected.
ATMOSPHERIC FATE: According to a model of gas/particle partitioning
of semivolatile organic compounds in the atmosphere, xylene, which
has an experimental vapor pressure of 7.99 mm Hg at 25 deg C, will
exist solely as a vapor in the ambient atmosphere. Vapor-phase xylene
is degraded in the atmosphere by reaction with
photochemically-produced hydroxyl radicals; the atmospheric lifetime
of xylene is about 14-26 hours. Ambient levels of xylene are detected
in the atmosphere due to large emissions of this compound.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
||No information available.
||No information available.
Section 15 - Regulatory Information
CAS# 108-38-3 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-38-3: Effective Date: 10/4/82; Sunset Date: 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-38-3: 1000 lb final RQ (Listed under ''Xylene, mixed); 454 kg final RQ (Listed un
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 108-38-3: acute, chronic, flammable.
This material contains m-Xylene (CAS# 108-38-3, 100%),which is
subject to the reporting requirements of Section 313 of SARA Title
III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-38-3 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 108-38-3 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
None of the chemicals in this product are considered highly hazardous
CAS# 108-38-3 can be found on the following state right to know
lists: California, New Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European Labeling in Accordance with EC Directives
R 10 Flammable.
R 20/21 Harmful by inhalation and in contact with
R 38 Irritating to skin.
S 25 Avoid contact with eyes.
WGK (Water Danger/Protection)
CAS# 108-38-3: No information available.
Canada - DSL/NDSL
CAS# 108-38-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2A.
Canadian Ingredient Disclosure List
CAS# 108-38-3 is listed on the Canadian Ingredient Disclosure List.
CAS# 108-38-3 (listed as xylenes (o-, m-, p- isomers)): OEL-ARAB Repub
lic of Egypt:TWA 0.5 ppm (0.9 mg/m3) OEL-AUSTRALIA:TWA 80 ppm (330 mg
/m3);STEL 150 ppm (655 mg/m3) OEL-BELGIUM:TWA 100 ppm (434 mg/m3);STE
L 150 ppm (651 mg/m3) OEL-CZECHOSLOVAKIA:TWA 200 mg/m3;STEL 1000 mg/m
3 OEL-DENMARK:TWA 50 ppm (217 mg/m3);Skin OEL-FINLAND:TWA 100 ppm (4
35 mg/m3);STEL 150 ppm;Skin OEL-FRANCE:TWA 100 ppm (435 mg/m3);STEL 1
50 ppm (650 mg/m3) OEL-GERMANY:TWA 100 ppm (440 mg/m3) OEL-HUNGARY:T
WA 100 mg/m3;STEL 300 mg/m3 OEL-JAPAN:TWA 100 ppm (430 mg/m3) OEL-TH
E NETHERLANDS:TWA 100 ppm (435 mg/m3);Skin OEL-THE PHILIPPINES:TWA 0.
1 mg/m3 OEL-POLAND:TWA 100 mg/m3 OEL-SWEDEN:TWA 50 ppm (200 mg/m3);S
TEL 100 ppm (450 mg/m3);Skin OEL-SWITZERLAND:TWA 100 ppm (436 mg/m3);
STEL 200 ppm (870 mg/m3) OEL-THAILAND:TWA 100 ppm (435 mg/m3) OEL-TU
RKEY:TWA 100 ppm (435 mg/m3) OEL-UNITED KINGDOM:TWA 100 ppm (435 mg/m
3);STEL 150 ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check A
CGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 12/12/1997
Revision #8 Date: 6/21/2001
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.