Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
106-44-5	p-Cresol	>98	203-398-6

Section 3 - Hazards Identification

Appearance: colorless to light yellow solid. Flash Point: 86.1 deg C.
Danger! Toxic. Causes eye and skin burns. Causes digestive and respiratory tract burns. May be fatal if inhaled. May cause allergic skin reaction. Harmful if swallowed or absorbed through the skin. May cause liver and kidney damage. Light sensitive. Material is a solid at room temperature that melts upon moderate heating into a combustible liquid with a flash point below 200°F(93.3°C). Hygroscopic (absorbs moisture from the air).
Target Organs: Kidneys, central nervous system, liver, respiratory system.


Potential Health Effects
Eye: Causes eye burns. May result in corneal injury. Contact with liquid is corrosive to the eyes and causes severe burns. May cause conjunctivitis and keratitis.
Skin: May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Causes severe skin irritation and burns. Initial contact may cause prickling and intense burning. Affected tissue may initially show white discoloration, wrinkling, and softening, which subsequently may become gangrenous.
Ingestion: May cause severe and permanent damage to the digestive tract. May cause vascular collapse and damage. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death. May cause kidney, liver and spleen damage. Rapidly absorbed from the gastrointestinal tract. Cresols may cause abnormalities of the central nervous system, respiratory system, spleen and pancreas.
Inhalation: May be fatal if inhaled. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause liver and kidney damage. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Causes chemical burns to the respiratory tract. May cause headache. May cause nausea and possible vomiting. Exposure to vapors or aerosols produced by high temperature processes may cause systemic absorption. If sufficient amounts are absorbed vascular collapse, shock, hypthermia, unconciousness and respiratory failure are possible.
Chronic: May cause liver and kidney damage. Repeated exposure may cause sensitization dermatitis. May cause appetite loss, diarrhea, skin abnormalities, and digestive tract disturbances.

Section 4 - First Aid Measures

Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May polymerize explosively when involved in a fire. Material is a solid at room temperature that melts upon moderate heating into a combustible liquid with a flash point below 200°F(93.3°C).
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Flash Point: 86.1 deg C ( 186.98 deg F)
Autoignition Temperature: 558.9 deg C ( 1,038.02 deg F)
Explosion Limits, Lower:1.1% @ 150C
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Provide ventilation. Evacuate unnecessary personnel.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Minimize dust generation and accumulation. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. If the water content is below approximately 0.3% and the temperature exceeds 268°F (120°C), violent corrosion of aluminum and its alloys may occur.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
p-Cresol	5 ppm TWA; Skin - potential significant contribution to overall exposure by the cutaneous r oute	2.3 ppm TWA; 10 mg/m3 TWA 250 ppm IDLH	5 ppm TWA; 22 mg/m3 TWA (listed under Cresol).

OSHA Vacated PELs: p-Cresol: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: colorless to light yellow
Odor: phenol-like
pH: Not available.
Vapor Pressure: 1 mm Hg @ 53 deg C
Vapor Density: 3.72 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 202.2 deg C
Freezing/Melting Point:35 deg C
Decomposition Temperature:Not available.
Solubility: 22.6g/L @ 40C.
Specific Gravity/Density:1.03 (water=1)
Molecular Formula:C7H8O
Molecular Weight:108.0554

Section 10 - Stability and Reactivity

Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Low melting point solid.
Conditions to Avoid: Incompatible materials, light, ignition sources, excess heat.
Incompatibilities with Other Materials: Oxidizing agents, strong acids, bases, active metals, coatings, nitric acid, plastics, rubber, aliphatic amines, amides, chlorosulfonic acid, oleum, alkalies.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, cresol.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:      
CAS# 106-44-5: GO6475000
LD50/LC50:
CAS# 106-44-5:
     Draize test, rabbit, eye: 103 mg Severe;
     Draize test, rabbit, skin: 517 mg/24H Severe;
     Inhalation, rat: LC50 = >710 mg/m3/1H;
     Inhalation, rat: LC50 = 29 mg/m3;
     Oral, mouse: LD50 = 344 mg/kg;
     Oral, mouse: LD50 = 160 mg/kg;
     Oral, rabbit: LD50 = 620 mg/kg;
     Oral, rat: LD50 = 207 mg/kg;
     Oral, rat: LD50 = 270 mg/kg;
     Skin, rabbit: LD50 = 301 mg/kg;
     Skin, rabbit: LD50 = 301 mg/kg;
     Skin, rat: LD50 = 750 mg/kg;
     Skin, rat: LD50 = 750 mg/kg;
.

Carcinogenicity:
CAS# 106-44-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information available.
Reproductive Effects: No information found
Mutagenicity: No information available.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Fish: Fathead Minnow: LC50 = 19-28.6 mg/L; 96 Hr.; UnspecifiedFish: LC50 = 19-28.6 mg/L; 96 Hr.; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 1.6 mg/L; 15 Minutes; Microtox test Goldfish (soft water) TLm=49.1-19ppm/24-96H Bluegill (soft water) TLm=22.2-20.8ppm/24-96H Fathead minnow (hard water) TLm=18-13.4ppm/24-96H Guppy (hard water) TLm=18-50ppm/24-96H
Environmental: In air, substance will react with photochemically-produced hydroxyl radicals (day) and nitrate radicals (night). In water, substance will biodegrade within days. Substance is mobile in most soils and will biodegrade.
Physical: No information available.
Other: Please refer to the Handbook of Environmental Fate and Exposure Data (Vol 1) for additional information.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	CRESOLS, SOLID	CRESOLS, SOLID
Hazard Class:	6.1	6.1(8)
UN Number:	UN3455	UN3455
Packing Group:	II	II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 106-44-5 is listed on the TSCA inventory.
Health & Safety Reporting List
     CAS# 106-44-5: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 106-44-5: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 106-44-5: immediate, fire.
Section 313
     This material contains p-Cresol (CAS# 106-44-5, >98%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 106-44-5 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 106-44-5 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 106-44-5 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, (listed as Cresol), Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T C
Risk Phrases:
     R 34 Causes burns.
     R 24/25 Toxic in contact with skin and if swallowed.

Safety Phrases:
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
     otection.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)
     CAS# 106-44-5: 2
Canada - DSL/NDSL
     CAS# 106-44-5 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B3, D1A, E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 106-44-5 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 5/05/1999
Revision #8 Date: 10/29/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.