Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
88-89-1	Picric acid	<70	201-865-9
7732-18-5	Water	>30	231-791-2

Section 3 - Hazards Identification

Appearance: yellow slurry.
Warning! Anhydrous material is shock-, friction-, and heat-sensitive. Highly unstable in crystalline form. Flammable solid. Causes severe eye and skin irritation with possible burns. Harmful if swallowed. May become explosive when allowed to dry out. May cause allergic skin reaction. Corrosive to carbon steel.
Target Organs: Kidneys, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation. May result in corneal injury. Experimentally, a solution of picric acid injected into the corneal stroma of the rabbit eye produced damage, even when the solution was neutralized quickly. Another report indicated the effects of picric acid on the eyes of workers that included irritation, corneal injury, and strange visual efects, that is, yellow-tainted vision.
Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Can dye the skin yellow. Historical reports suggest that even dilute concentrations of picric acid (0.2 - 1%) can be absorbed through broken skin causing symptoms such as headache, shivering, and fever. The duration of contact is not known and there may have been other contributing factors. ACGIH removed their skin notation in 1990 since data available for review did not substantiate the ability of picric acid to penetrate the intact skin, and contribute to systemic toxicity.
Ingestion: Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. May cause headache. Picric acid is toxic following ingestion, based on animal toxicity values and case reports of suicidal ingestion. If ingested, picric acid may cause a bitter taste in the mouth, headache, dizziness, nausea, vomiting, diarrhea, and kidney injury (with the inability to urinate or painful, difficult urination). High doses may damage the red blood cells and cause acute hepatitis.
Inhalation: May cause respiratory tract irritation. Material has a low vapor pressure at room temperature, so exposure to vapor is not likely. In normal use, picric acid is a wetted solid or solution that does not readily form a vapor. Since dry picric acid is explosive, stringent handling procedures are followed. It is therefore unlikely that picric acid would pose an inhalation hazard.
Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause kidney injury. Prolonged or repeated exposure may cause yellow staining of the skin and conjunctiva and "yellow vision". Historical reports describe blistering and flaking of the skin, especially around the mouth and sides of the nose, in employees exposed to picric

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Exposure to heat may promote violent decomposition. This material is an explosion hazard when exposed to heat, mechanical shock, or friction. This material poses an explosion hazard when dry. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products.
Extinguishing Media: Do NOT use carbon dioxide. Do NOT use halogenated agents. Use flooding quantities of water as spray. Cool containers with flooding quantities of water until well after fire is out.
Flash Point: 150 deg C ( 302.00 deg F)
Autoignition Temperature: 300 deg C ( 572.00 deg F)
Explosion Limits, Lower:None reported.
Upper: None reported.
NFPA Rating: (estimated) Health: 3; Flammability: 4; Instability: 4

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Remove all sources of ignition. If the material is dry, explosives experts may be necessary to dispose of the spill. Isolate area and deny entry. Wet area to prevent drying out. Provide ventilation. Evacuate unnecessary personnel.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Material is heat, shock and/or friction sensitive. Use care in handling and storage. Loosen closure cautiously before opening. Avoid breathing dust, mist, or vapor. Avoid contact with eyes, skin, and clothing. Keep away from heat, sparks and flame. Container should be opened by a technically qualified person. Avoid mechanical shock and friction. Do not allow water to evaporate from product. Dry picric acid is explosive. Dried crystals may be present within threads of screw top containers and present a detonation hazard when opening. If a bottle of picric acid is old and has a metal cap, care must be exercised as highly shock sensitive metal picrates may have formed.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep container closed to prevent drying out. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from metals. Material can explode if dry. Do not store on concrete. Separate from organic materials. Protect from freezing.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
Picric acid	0.1 mg/m3 TWA	0.1 mg/m3 TWA 75 mg/m3 IDLH	0.1 mg/m3 TWA
Water	none listed	none listed	none listed

OSHA Vacated PELs: Picric acid: 0.1 mg/m3 TWA Water: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Slurry
Appearance: yellow
Odor: odorless
pH: 1.3 (1.4% sat aq soln)
Vapor Pressure: Negligible
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not applicable.
Freezing/Melting Point:121.8 deg C
Decomposition Temperature:300 deg C
Solubility: 1.27 g/100ml
Specific Gravity/Density:1.767
Molecular Formula:C6H2(NO2)3OH
Molecular Weight:229.0369

Section 10 - Stability and Reactivity

Chemical Stability: Do not allow water to evaporate from product. Dry picric acid is explosive. Explodes above 572°F (300°C) with release of oxides of nitrogen.
Conditions to Avoid: High temperatures, mechanical shock, ignition sources, Do not allow water to evaporate from product. Dry picric acid is explosive..
Incompatibilities with Other Materials: Metals, reducing agents, bases, amines, ammonia, concrete (forms friction sensitive calcium picrate).
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

RTECS#:      
CAS# 88-89-1: TJ7875000      
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 88-89-1:
     Oral, rat: LD50 = 200 mg/kg;
.

CAS# 7732-18-5:
     Oral, rat: LD50 = >90 mL/kg;
.

Carcinogenicity:
CAS# 88-89-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: An outbreak of hematuria (blood in the urine) among U.S. Navy personnel aboard ships anchored at Wakayama, Japan, in 1946 was attributed to the ingestion of picric acid in drinking water.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: No data available. Rainbow trout (Salmo gairdneri), LC50=109.6 mg/L/96 hr; American oysters (Crassotrea virginica), LC50=254.9 mg/L/14 hr; Bluegill (Lepomis macrachirus), LC50=193 mg/L/24 hr
Environmental: Picric acid may undergo photolysis to picramic acid in alkaline but not acidic water. Because of its low pKa, 0.38, picric acid is expected to exist largely in its anionic form. Atmospheric partitioning is not expected to occur. It is not expected to volatilize in soil.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	Trinitrophenol, WETTED WITH NOT LESS than 30% water, by mass	Trinitrophenol
Hazard Class:	4.1	1.1
UN Number:	UN1344	UN0154
Packing Group:	I	II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 88-89-1 is listed on the TSCA inventory.
     CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 88-89-1: immediate, delayed, fire, sudden release of pressure, reactive.
Section 313
     This material contains Picric acid (CAS# 88-89-1, <70%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 88-89-1 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T F
Risk Phrases:
     R 1 Explosive when dry.
     R 11 Highly flammable.
     R 23/24/25 Toxic by inhalation, in contact with skin and if
     swallowed.
     R 4 Forms very sensitive explosive metallic compounds.
     R 43 May cause sensitization by skin contact.

Safety Phrases:
     S 28 After contact with skin, wash immediately with...
     S 35 This material and its container must be disposed of in a safe w
     ay.
     S 37 Wear suitable gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)
     CAS# 88-89-1: 2
     CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
     CAS# 88-89-1 is listed on Canada's DSL List.
     CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B4, D1B, D2B, E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 88-89-1 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 5/13/1998
Revision #5 Date: 9/26/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.