Material Safety Data Sheet

ACC# 18940
Section 1 - Chemical Product and Company Identification

MSDS Name: Piperidine
Catalog Numbers: AC147180000, AC147180010, AC147180025, AC147180050, AC147181000, AC147182500, AC147185000, BP1210-500, P125-100, P125-500
Hexahydropyridine; Azacyclohexane; Cyclopentimine; Hexazine
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
Emergency Number:
For CHEMTREC assistance, call:
For International CHEMTREC assistance, call:

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
110-89-4 Piperidine > 99 203-813-0

Section 3 - Hazards Identification


Appearance: clear or slight yellow liquid. Flash Point: 16 deg C.
Danger! Causes severe eye and skin burns. Flammable liquid and vapor. Harmful if absorbed through skin or if inhaled. Causes severe digestive tract burns. Causes severe respiratory tract burns. May cause central nervous system effects.
Target Organs: Eyes, nervous system, skin, mucous membranes.

Potential Health Effects
Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Contact may cause ulceration of the conjunctiva and cornea. Eye damage may be delayed. May cause conjunctivitis. May cause blindness.
Skin: Harmful if absorbed through the skin. May be absorbed through the skin. If absorbed, causes symptoms similar to those of ingestion. Penetration may continue for several days. Causes severe skin irritation and burns.
Ingestion: Harmful if swallowed. May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. Can cause nervous system damage. May cause tremors and convulsions.
Inhalation: May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. May cause effects similar to those described for ingestion. Damage may be delayed. May cause bronchial pneumonia.
Chronic: Repeated inhalation may cause chronic bronchitis. Prolonged or repeated contact may cause skin necrosis and/or ulceration of the skin. May cause chronic cough.

Section 4 - First Aid Measures

Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Gently lift eyelids and flush continuously with water. Ex tensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Vapor may explode if ignited in a confined area. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May polymerize explosively when involved in a fire. Containers may explode when heated.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Flash Point: 16 deg C ( 60.80 deg F)
Autoignition Temperature: 320 deg C ( 608.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 3; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Provide ventilation.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Flammables-area. Corrosives area.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Ventilation fans and other electrical service must be non-sparking and have an explosion-proof design.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Piperidine none listed none listed none listed

OSHA Vacated PELs: Piperidine: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Liquid
Appearance: clear or slight yellow
Odor: pepper-like odor
pH: 12.6
Vapor Pressure: 40 mm Hg @29.9
Vapor Density: 3.0 (air=1)
Evaporation Rate:Not available.
Viscosity: 1.46 mPa s 20 C
Boiling Point: 106 deg C
Freezing/Melting Point:-13 deg C
Decomposition Temperature:500 deg C
Solubility: Completely miscible in water
Specific Gravity/Density:0.8622 at 20°C
Molecular Formula:C5H11N
Molecular Weight:85.0837

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials: Acids; acid chlorides; acid anhydrides; carbon dioxide; strong oxidizing agents; dicyanofurazan; N-nitrosoacetanilide;1-Perchlorylpiperdine
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen gas.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

CAS# 110-89-4: TM3500000
CAS# 110-89-4:
     Draize test, rabbit, eye: 250 ug/24H Severe;
     Draize test, rabbit, skin: 5 mg/24H Severe;
     Inhalation, mouse: LC50 = 6000 mg/m3/2H;
     Oral, mouse: LD50 = 30 mg/kg;
     Oral, rabbit: LD50 = 145 mg/kg;
     Oral, rat: LD50 = 400 mg/kg;
     Skin, rabbit: LD50 = 276 mg/kg;

CAS# 110-89-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: Inhalation, Rat: TCLo = 3 mg/m3/24H - fetotoxic effects. Inhalation, rat: TCLo = 100 mg/m3/24H - effected litter size
Mutagenicity: Mutagenic at 5050 ĉmol/L in mouse lymphocyte.
Neurotoxicity: Intravenous, rabbit: LDLo = 160 mg/kg. Caused spastic paralysis and convulsions or effect on seisure threshold.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Hazard Class: 8 8(3)
UN Number: UN2401 UN2401
Packing Group: I I
Additional Info:FLASHPOINT 16 C

Section 15 - Regulatory Information


     CAS# 110-89-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     CAS# 110-89-4: 1000 lb TPQ
SARA Codes
     CAS # 110-89-4: immediate, fire.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
     None of the chemicals in this product are considered highly hazardous by OSHA.
     CAS# 110-89-4 can be found on the following state right to know lists: New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T F C
Risk Phrases:

     R 11 Highly flammable.
     R 34 Causes burns.

Safety Phrases:

     S 16 Keep away from sources of ignition - No smoking.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 27 Take off immediately all contaminated clothing.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 110-89-4: 1
Canada - DSL/NDSL
     CAS# 110-89-4 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, D1B, E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #9 Date: 10/29/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.