Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
7632-00-0	Sodium nitrite	>97	231-555-9

Section 3 - Hazards Identification

Appearance: white to light yellow crystals.
Danger! May be fatal if inhaled. Strong oxidizer. Contact with other material may cause a fire. Harmful if swallowed. Causes eye, skin, and respiratory tract irritation. May cause methemoglobinemia. This substance has caused adverse reproductive and fetal effects in animals. Air sensitive. Hygroscopic (absorbs moisture from the air).
Target Organs: Blood, cardiovascular system, smooth muscle.


Potential Health Effects
Eye: Causes eye irritation. May cause conjunctivitis. May cause permanent corneal opacification.
Skin: Causes skin irritation. May be absorbed through the skin.
Ingestion: Harmful if swallowed. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death. Causes digestive tract irritation. Ingestion may cause weakness, muscular incoordination, fine tremors, loss of reflexes, convulsions and possible death from circulatory collapse. Ingestion may cause a decrease in blood pressure, rapid pulse and visual disturbances.
Inhalation: May be fatal if inhaled. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death. May cause acute pulmonary edema, asphyxia, chemical pneumonitis, and upper airway obstruction caused by edema.
Chronic: May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. Animal studies have reported the development of tumors. Sodium nitrate may react with secondary or tertiary amines to form nitrosamines (certain nitrosamines are cancer suspect agents).

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician: Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. If cyanosis is severe, intravenous injection of Methylene Blue, 1mg/kg of body weight may be of value.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Strong oxidizer. Contact with other material may cause fire. Use water with caution and in flooding amounts. May explode from heat or contamination. May accelerate burning if involved in a fire.
Extinguishing Media: Use water only! Contact professional fire-fighters immediately. Cool containers with flooding quantities of water until well after fire is out. For large fires, flood fire area with water from a distance. Do NOT use dry chemicals, CO2, Halon or foams.
Flash Point: Not applicable.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 1; Special Hazard: OX

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Keep combustibles (wood, paper, oil, etc.,) away from spilled material.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid contact with clothing and other combustible materials. Do not ingest or inhale. Handle under an inert atmosphere. Store protected from air. Use only in a chemical fume hood.
Storage: Do not store near combustible materials. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from moisture. Store under an inert atmosphere. Avoid storage on wood floors.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
Sodium nitrite	none listed	none listed	none listed

OSHA Vacated PELs: Sodium nitrite: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties

Physical State: Crystals
Appearance: white to light yellow
Odor: odorless
pH: ~ 9
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 320 deg C
Freezing/Melting Point:271 deg C
Decomposition Temperature:320 deg C
Solubility: Soluble.
Specific Gravity/Density:2.168
Molecular Formula:NaNO2
Molecular Weight:69

Section 10 - Stability and Reactivity

Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Unstable if heated, may explode at temperatures greater than 533°C.
Conditions to Avoid: Ignition sources, dust generation, exposure to air, exposure to moist air or water, temperatures above 320°C.
Incompatibilities with Other Materials: Reducing agents, acids, amines, chlorates, permanganates, cyanides (e.g. potassium cyanide, sodium cyanide), metals as powders (e.g. hafnium, raney nickel), hypophosphites, sulfites, tannic acid, organic matter, antipyrine, ammonium salts, acetanilide, iodides, mercury salts, moisture, air, activated carbon, vegetable astringents.
Hazardous Decomposition Products: Oxides of nitrogen, irritating and toxic fumes and gases.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

RTECS#:      
CAS# 7632-00-0: RA1225000; RA1425000
LD50/LC50:
CAS# 7632-00-0:
     Draize test, rabbit, eye: 500 mg/24H Mild;
     Inhalation, rat: LC50 = 5.5 mg/m3/4H;
     Oral, mouse: LD50 = 175 mg/kg;
     Oral, rabbit: LD50 = 186 mg/kg;
     Oral, rat: LD50 = 180 mg/kg;
.

Carcinogenicity:
CAS# 7632-00-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Oral, rat: TDLo = 2190 gm/kg/2Y-C (Tumorigenic - Carcinogenic by RTECS criteria - Gastrointestinal - tumors).; Oral, rat: TD = 91 gm/kg/2Y-C (Tumorigenic - equivocal tumorigenic agent by RTECS criteria - Skin and Appendages - tumors and Reproductive - Tumorigenic effects - testicular tumors).; Oral, rat: TD = 40 gm/kg/56W-C - (Tumorigenic - neoplastic by RTECS criteria - Liver - tumors).
Teratogenicity: Oral, rat: TDLo = 660 mg/kg (female 1-22 day(s) after conception) Effects on Embryo or Fetus - fetal death and Effects on Newborn - growth statistics (e.g.%, reduced weight gain).; Oral, rat: TDLo = 10280 mg/kg (female 1-22 day(s) after conception and lactating female 20 day(s) post-birth) Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4).; Oral,mouse: TDLo = 280 mg/kg (female 1-14 day(s) after conception) Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow).
Reproductive Effects: Oral, mouse: TDLo = 1200 mg/kg (female 6-15 day(s) after conception) Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea).; Oral, mouse: TDLo = 1680 mg/kg (male 14 day(s) pre-mating) Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females).; Oral, mouse: TDLo = 840 mg/kg (male 14 day(s) pre-mating) Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count).
Mutagenicity: Unscheduled DNA Synthesis: Human, HeLa cell = 6 mmol/L.; DNA Inhibition: Human, Fibroblast = 2000 ppm.; DNA Inhibition: Human Cells - not otherwise specified = 725 umol/L.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Fish: Rainbow trout: LC50 = 0.19-0.39 mg/L; 96 Hr; Flow-through bioassayFish: Mosquito Fish: TLm =8.1 ppm; 24 Hr; Highly turbid waterFish: Creek chub: Critical range = 400-2000 ppm; 24 Hr; Detroit River No data available.
Environmental: In water sodium nitrite dissociates completely and under aerobic conditions the nitrite ions are oxidized to nitrates.
Physical: No information available.
Other: Harmful to aquatic life in very low concentrations.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	SODIUM NITRITE	SODIUM NITRITE
Hazard Class:	5.1	5.1(6.1)
UN Number:	UN1500	UN1500
Packing Group:	III	III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 7632-00-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 7632-00-0: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 7632-00-0: immediate, delayed, fire.
Section 313
     This material contains Sodium nitrite (CAS# 7632-00-0, >97%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 7632-00-0 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 7632-00-0 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T O N
Risk Phrases:
     R 25 Toxic if swallowed.
     R 8 Contact with combustible material may cause fire.
     R 50 Very toxic to aquatic organisms.

Safety Phrases:
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)
     CAS# 7632-00-0: 2
Canada - DSL/NDSL
     CAS# 7632-00-0 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of C, D1B, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 7632-00-0 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 7/02/1999
Revision #9 Date: 2/15/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.