Material Safety Data Sheet
Section 1 - Chemical Product and Company Identification
MSDS Name: Tetrachloroethylene
C182 20, C182 4, C182-20, C182-4, C18220, C1824, O4586 4, O4586-4, O45864
Ethylene tetrachloride; Tetrachlorethylene; Perchloroethylene;
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|| 99.0+ ||204-825-9
Hazard Symbols: XN N
Risk Phrases: 40 51/53
Section 3 - Hazards Identification
Appearance: clear, colorless liquid.
Irritant. May cause severe eye and skin irritation with possible
burns. May cause central nervous system depression. May cause liver
and kidney damage. May cause reproductive and fetal effects. May
cause cancer based on animal studies. Caution! May
cause respiratory tract irritation.
Target Organs: Kidneys, central nervous system,
Potential Health Effects
Contact with eyes may cause severe irritation, and possible eye
May cause severe irritation and possible burns.
May cause central nervous system depression, kidney damage, and
liver damage. Symptoms may include: headache, excitement, fatigue,
nausea, vomiting, stupor, and coma. May cause gastrointestinal
irritation with nausea, vomiting and diarrhea.
Inhalation of vapor may cause respiratory tract irritation. May
cause central nervous system effects including vertigo, anxiety,
depression, muscle incoordination, and emotional instability.
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause respiratory tract cancer. May cause adverse
nervous system effects including muscle tremors and incoordination.
May cause liver and kidney damage. May cause reproductive and fetal
Section 4 - First Aid Measures
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Get medical aid if irritation develops or persists. Wash clothing
before reuse. Flush skin with plenty of soap and water.
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Containers may explode in the heat of a fire.
Vapors may be heavier than air. They can spread along the ground and
collect in low or confined areas.
Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire. For small fires, use dry chemical,
carbon dioxide, or water spray. For large fires, use dry chemical,
carbon dioxide, alcohol-resistant foam, or water spray. Cool
containers with flooding quantities of water until well after fire is
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
(estimated) Health: 2; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Flush down
the spill with a large amount of water. Remove all sources of
ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - Handling and Storage
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Do not reuse this
container. Avoid breathing vapors from heated material. Avoid contact
with skin and eyes. Keep container tightly closed. Keep away from
flames and other sources of high temperatures that may cause material
to form vapors or mists.
Keep away from heat and flame. Store in a cool, dry place. Keep
containers tightly closed.
Section 8 - Exposure Controls, Personal Protection
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
||OSHA - Final PELs|
|Tetrachloroethylene||25 ppm TWA; 100 ppm STEL
|| 150 ppm IDLH||100 ppm TWA; 200 ppm Ceiling
OSHA Vacated PELs:
25 ppm TWA; 170 mg/m3 TWA
Personal Protective Equipment
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Appearance: clear, colorless
Odor: sweetish odor
pH: Not available.
Vapor Pressure: 15.8 mm Hg
Vapor Density: 5.2
Evaporation Rate:9 (ether=100)
Viscosity: 0.89 mPa s 20 deg C
Boiling Point: 121 deg C
Freezing/Melting Point:-22.3 deg C
Decomposition Temperature:150 deg C
Solubility: Nearly insoluble in water.
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, excess heat.
Incompatibilities with Other Materials:
Strong bases, metals, liquid oxygen, dinitrogen tetroxide.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
CAS# 127-18-4: KX3850000
Draize test, rabbit, eye: 162 mg Mild;
test, rabbit, eye: 500 mg/24H Mild;
Draize test, rabbit, skin:
810 mg/24H Severe;
Draize test, rabbit, skin: 500 mg/24H
Inhalation, mouse: LC50 = 5200 ppm/4H;
LC50 = 34200 mg/m3/8H;
Oral, mouse: LD50 = 8100 mg/kg;
rat: LD50 = 2629 mg/kg;
ACGIH: A3 - Animal Carcinogen
California: carcinogen; initial date 4/1/88
NIOSH: potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2A carcinogen
Epidemiologic studies have given inconsistent results. Studi
es have shown that tetrachloroethylene has not caused canc
er in exposed workers. The studies have serious weakne
sses such as mixed exposures. In tests with rats and mice, i
t appeared that tissue destruction or peroxisome prolifera
tion rather than genetic mechanisms were the cause of
the observed increases in normally occurring cancers. The
oral mouse TDLo that was tumorigenic was 195 gm/kg/50W-I.
Has caused musculoskeletal abnormalities. Has caused morphological
transformation at a dose of 97mol/L in a study using rat embryos.
Has caused behavioral, biochemical, and metabolic effects on newborn
rats when the mother was exposed to the TCLo of 900 ppm/7H at 7-13
days after conception. A dose of 300 ppm/7H 6-15 days after
conception caused post-implantation mortality.
No information available.
Not mutagenic in Escherichia coli. No mutagenic effects were seen in
rat liver after exposure at 200 ppm for 10 weeks. No chromosome
changes were seen in the bone marrow cells of exposed mice.
A case of 'obstructive jaundice' in a 6-week old infant has
been attributed to tetrachloroethylene in breast milk.
Section 12 - Ecological Information
Fish: Rainbow trout: LC50 = 5.28 mg/L; 96 Hr.; Static Condition, 12
Fathead Minnow: LC50 = 18.4 mg/L; 96 Hr.;
Bluegill/Sunfish: LC50 = 12.9 mg/L; 96
Hr.; Static Condition
ria: Phytobacterium phosphoreum: EC50 =
120.0 mg/L; 30 minutes; Microtox test
No data available.
In soil, substance will rapidly evaporate. In water, it will
evaporate. In air, it can be expected to exist in the vapor phase.
No information available.
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 127-18-4: waste number
Section 14 - Transport Information
Section 15 - Regulatory Information
CAS# 127-18-4 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 127-18-4: Effective Date: 6/1/87; Sunset Date: 6/1/97
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 127-18-4: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 127-18-4: acute.
This material contains Tetrachloroethylene (CAS# 127-18-4, 99
0%),which is subject to the reporting requirements of Section 313 of
SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 127-18-4 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
CAS# 127-18-4 is listed as a Priority Pollutant under the Clean Water
CAS# 127-18-4 is listed as a Toxic Pollutant under the Clean Water
None of the chemicals in this product are considered highly hazardous
CAS# 127-18-4 can be found on the following state right to know
lists: California, New Jersey, Pennsylvania, Minnesota,
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains Tetrachloroethylene, a chemical known
to the state of California to cause cancer.
California No Significant Risk Level:
CAS# 127-18-4: 14 ug/day NSRL
European Labeling in Accordance with EC Directives
R 40 Limited evidence of a carcinogenic effect.
R 51/53 Toxic to aquatic organisms; may cause
long-term adverse effects in the aquatic environment.
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 127-18-4: 3
Canada - DSL/NDSL
CAS# 127-18-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2A.
Canadian Ingredient Disclosure List
CAS# 127-18-4 is listed on the Canadian Ingredient Disclosure List.
CAS# 127-18-4: OEL-ARAB Republic of Egypt:TWA 5 ppm (35 mg/m3);Skin
OEL-AUSTRALIA:TWA 50 ppm (335 mg/m3);STEL 150 ppm;CAR OEL-BELGIUM:TW
A 50 ppm (339 mg/m3);STEL 200 ppm (1368 mg/m3) OEL-CZECHOSLOVAKIA:TWA
250 mg/m3;STEL 1250 mg/m3 OEL-DENMARK:TWA 30 ppm (200 mg/m3);Skin O
EL-FINLAND:TWA 50 ppm (335 mg/m3);STEL 75 ppm (520 mg/m3);Skin OEL-FR
ANCE:TWA 50 ppm (335 mg/m3) OEL-GERMANY:TWA 50 ppm (345 mg/m3);Carcin
ogen OEL-HUNGARY:STEL 50 mg/m3;Skin;Carcinogen OEL-JAPAN:TWA 50 ppm
(340 mg/m3) OEL-THE NETHERLANDS:TWA 35 ppm (240 mg/m3);Skin OEL-THE
PHILIPPINES:TWA 100 ppm (670 mg/m3) OEL-POLAND:TWA 60 mg/m3 OEL-RUSS
IA:TWA 50 ppm;STEL 10 mg/m3 OEL-SWEDEN:TWA 10 ppm (70 mg/m3);STEL 25
ppm (170 mg/m3) OEL-SWITZERLAND:TWA 50 ppm (345 mg/m3);STEL 100 ppm;S
kin OEL-THAILAND:TWA 100 ppm;STEL 200 ppm OEL-UNITED KINGDOM:TWA 50
ppm (335 mg/m3);STEL 15 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA
check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 6/17/1999
Revision #3 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.