MSDS Name: Tetrahydrofuran, 99.5+%, for spectroscopy.
Catalog Numbers:
AC222160000, AC222160010, AC222162500, AC222165000, AC268290000,
AC268290010, AC268290025, AC268290040, AC268295000, AC610100040,
AC610450010, AC610451000, AC610921000, BP1140-1, BP11401LC, NC9058040,
NC9234867, NC9326115, T397RS-200ASME, T400RS-50, T421-1, T421RS-19,
T421RS19, T421RS50, T422-1, T422RS-200, T422RS-50, T422RS200, T424-4,
T425-1, T425-4, T425N219, T425RS-115, T425RS-28, T425RS-50, T425RS115,
T425RS19, T425SK-1, T425SK-4, T425SS-115, T425SS-19, T425SS-200, T425SS-50,
T427-1, T427-4, T427POP200, T427RS-200, T427RS115, T427RS200, T427RS28,
T427SK-4, T427SS115, T427SS19, T427SS200, T427SS28, T427SS50
Synonyms:
Diethylene oxide; 1,4-Epoxybutane; Tetramethylene oxide; THF;
Oxacyclopentane.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Appearance: colorless liquid. Flash Point: -14 deg C.
Danger! Highly flammable. Causes eye and
respiratory tract irritation. May form explosive peroxides.
Hygroscopic (absorbs moisture from the air).
Target Organs: Kidneys, central nervous system,
liver, respiratory system, eyes, skin.
Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye
burns. Vapors may cause eye irritation.
Damage may be permanent.
Skin:
Causes skin irritation. May be absorbed through the skin. If
absorbed, causes symptoms similar to those of inhalation.
THF is not a skin sensitizer in animals.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause central nervous system depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Vapors may cause dizziness or suffocation. Inhalation may
cause coughing, difficulty breathing and loss of consciousness.
Causes irritation of the mucous membrane and upper respiratory tract.
Inhalation of tetrahydrofuran vapors may cause abnormal liver
function as detected by laboratory tests. (Dupont)
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause liver and kidney damage. May cause lung damage.
Narcotic in high concentrations.
Data show carcinogenic activity in the liver and kidneys of
laboratory animals. The kidney tumors were by a mechanism that has no
relevance in humans.