Material Safety Data Sheet
Sodium nitroprusside dihydrate
ACC# 30681
Section 1 - Chemical Product and Company Identification |
MSDS Name: Sodium nitroprusside dihydrate
Catalog Numbers:
AC211640000, AC211640250, AC211641000, AC211645000, AC424360000,
AC424360250, AC424361000, AC424365000, S350-100
Synonyms:
Nipride dihydrate; Disodium nitroprusside dihydrate; Sodium
nitroferricyanide dihydrate; Sodium nitrosylpentacyanoferrate(III)
dihydrate; Sodium nitroprusside dihydrate; Disodium
pentacyanonitrosylferrate dihydrate; SNP.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
13755-38-9 |
Sodium nitroferricyanide dihydrate |
>99.8 | unlisted |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: bright red crystals.
Warning! Toxic if swallowed, inhaled or absorbed
through the skin. Contact with acids liberates hydrogen cyanide, a
very toxic, flammable gas or liquid. May cause eye and skin
irritation. May cause respiratory tract irritation. Hygroscopic
(absorbs moisture from the air).
Target Organs: Blood, central nervous system,
cardiovascular system.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Absorption into the body may cause
cyanosis (bluish discoloration of skin due to deficient oxygenation
of the blood). Toxic in contact with skin. May be metabolized to
cyanide which in turn acts by inhibiting cytochrome oxidase impairing
cellular respiration.
Ingestion:
May cause irritation of the digestive tract. Metabolism may release
cyanide, which may result in headache, dizziness, weakness,
collapse, unconsciousness and possible death. May cause cyanosis
(bluish discoloration of skin due to deficient oxygenation of the
blood). Ingestion may result in symptoms similar to cyanide poisoning
which is characterized by asphyxiation. Large doses of cyanide may
result in suddden loss of consciousness and prompt death; small
doses will prolong the above symptoms 1 to 2 hours. Toxic if
swallowed.
Inhalation:
May cause respiratory tract irritation. Toxic if inhaled. May be
metabolized to cyanide which in turns act by inhibiting cytochrome
oxidase impairing cellular respiration.
Sodium nitroprusside dihydrate releases NO (nitric oxide) in vivo,
induces vasodilation, and inhibits platelet aggregation.
Chronic:
May be metabolized to cyanide which in turn acts by inhibiting
cytochrome oxidase impairing cellular respiration. Chronic exposure
to cyanide solutions may lead to the development of a "cyanide" rash,
characterized by itching, and by macular, papular, and vesicular
eruptions, and may be accompanied by secondary infections. Exposure
to small amounts of cyanide compounds over long periods of time is
reported to cause loss of appetite, headache, weakness, nausea,
dizziness, and symptoms of irritation of the upper respiratory tract
and eyes.
Section 4 - First Aid Measures
|
Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid. Wash
clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Combustion
by-products include oxides of nitrogen and hydrogen cyanide.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 3; Flammability: 1; Instability: 1
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Wear a self contained breathing apparatus and
appropriate personal protection. (See Exposure Controls, Personal
Protection section). Sweep up, then place into a suitable container
for disposal. Avoid generating dusty conditions. Provide
ventilation. Do not let this chemical enter the environment.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Minimize dust generation and
accumulation. Do not get in eyes, on skin, or on clothing. Keep
container tightly closed. Do not ingest or inhale. Use only in a
chemical fume hood. Do not breathe dust.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from moisture.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits. Use only under a chemical fume hood.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Sodium nitroferricyanide dihydrate
|
1 mg/m3 TWA (as Fe) (listed under Iron salts (soluble)).
|
1 mg/m3 TWA (as Fe) (listed under Iron salts (soluble)).
|
none listed
|
Sodium nitroferricyanide, anhydrous
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Sodium nitroferricyanide dihydrate:
No OSHA Vacated PELs are listed for this chemical.
Sodium nitroferricyanide, anhydrous:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
|
Physical State: Crystals
Appearance: bright red
Odor: practically odorless
pH: 5 (5% aq. solution)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:1.72 g/cm3
Molecular Formula:C5FeN6O.Na2.2H2O
Molecular Weight:215.8866
Section 10 - Stability and Reactivity
|
Chemical Stability:
Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid:
Incompatible materials, dust generation, exposure to moist air or
water, temperatures above 190°C.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, acids.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide,
sodium oxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
|
RTECS#:
CAS# 13755-38-9:
LJ8925000
CAS# 14402-89-2:
LJ8750000
LD50/LC50:
Not available.
CAS# 14402-89-2:
Oral, mouse:
LD50 = 61 mg/kg;
Oral, rabbit:
LD50 = 34 mg/kg;
Oral, rat: LD50 =
99 mg/kg;
.
Carcinogenicity:
CAS# 13755-38-9:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 14402-89-2:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
No information found
Teratogenicity:
Nitroprusside was not teratogenic when tested in rats. Use
of nitroprusside during human pregnancy has been
described, both for hypertensive emergencies and to induce
hypotension, as in aneurysm surgery.No fetal problems have
been attributed to drug therapy. Because nitroprusside can
also be a source of cyanide, there has been concern that
maternal therapy might produce cyanide toxicity in the
offspring.
Reproductive Effects:
See actual entry in RTECS for complete information.
Mutagenicity:
See actual entry in RTECS for complete information.
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
No information available.
Environmental:
No information available.
Physical:
No information available.
Other:
Do not empty into drains.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
CYANIDES, INORGANIC SOLID, N.O.S. (Sodium nitroferricyanide dihydrate) |
CYANIDES, INORGANIC SOLID, N.O.S. (Sodium nitroferricyanide dihydrate) |
Hazard Class: |
6.1 |
6.1 |
UN Number: |
UN1588 |
UN1588 |
Packing Group: |
II |
II |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 13755-38-9 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
CAS# 14402-89-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 13755-38-9: immediate, delayed.
CAS # 14402-89-2: immediate, delayed.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 13755-38-9 can be found on the
following state right to know lists: California, (listed as Iron
salts (soluble)), Minnesota, (listed as Iron salts (soluble)).
CAS# 14402-89-2 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin and if
swallowed.
R 32 Contact with acids liberates very toxic gas.
Safety Phrases:
S 36/37 Wear suitable protective clothing and gloves.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 50A Do not mix with acids.
WGK (Water Danger/Protection)
CAS# 13755-38-9: 2
CAS# 14402-89-2: No information available.
Canada - DSL/NDSL
CAS# 14402-89-2 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 13755-38-9 is not listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 12/16/1997
Revision #10 Date: 8/05/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.