Material Safety Data Sheet
Buffer Concentrate pH 10.00

ACC# 41139
Section 1 - Chemical Product and Company Identification

MSDS Name: Buffer Concentrate pH 10.00
Catalog Numbers: NC9201792, NC9244269, NC9418512, NC9684263, S799292, SB141-500, XXSB14110LI, XXSB14110LIX
Synonyms:
None.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
7732-18-5 Water 90.0 231-791-2
7447-40-7 Potassium chloride 4.0 231-211-8
10043-35-3 Boric acid 3.0 233-139-2
1310-73-2 Sodium hydroxide 1.7 215-185-5
139-33-3 Disodium EDTA 0.9 205-358-3

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear colorless liquid.
Caution! May cause eye, skin, and respiratory tract irritation. This is expected to be a low hazard for usual industrial handling.
Target Organs: None.


Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause mild skin irritation.
Ingestion: Low hazard for usual industrial handling. May cause gastric disturbances and electrolytic imbalance.
Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling.
Chronic: No information found.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medi cal aid.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Water none listed none listed none listed
Potassium chloride none listed none listed none listed
Boric acid 2 mg/m3 TWA (inhalable fraction, listed under Borate compounds, inorganic); 6 mg/m3 STEL (inhalable fraction, listed under Borate compounds, inorganic) none listed none listed
Sodium hydroxide 2 mg/m3 Ceiling 10 mg/m3 IDLH 2 mg/m3 TWA
Disodium EDTA none listed none listed none listed

OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical. Potassium chloride: No OSHA Vacated PELs are listed for this chemical. Boric acid: No OSHA Vacated PELs are listed for this chemical. Sodium hydroxide: No OSHA Vacated PELs are listed for this chemical. Disodium EDTA: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear colorless
Odor: none reported
pH: 10.0
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:Mixture
Molecular Weight:Not applicable.

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: None reported.
Incompatibilities with Other Materials: None reported.
Hazardous Decomposition Products: None.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 7732-18-5: ZC0110000      
CAS# 7447-40-7: TS8050000      
CAS# 10043-35-3: ED4550000; ED4560000      
CAS# 1310-73-2: WB4900000      
CAS# 139-33-3: AH4375000
LD50/LC50:
CAS# 7732-18-5:
     Oral, rat: LD50 = >90 mL/kg;
.

CAS# 7447-40-7:
     Draize test, rabbit, eye: 500 mg/24H Mild;
     Oral, mouse: LD50 = 1500 mg/kg;
     Oral, rat: LD50 = 2600 mg/kg;
.

CAS# 10043-35-3:
     Oral, mouse: LD50 = 3450 mg/kg;
     Oral, rat: LD50 = 2660 mg/kg;
     Oral, rat: LD50 = 2500 mg/kg;
.

CAS# 1310-73-2:
     Draize test, rabbit, eye: 400 ug Mild;
     Draize test, rabbit, eye: 1% Severe;
     Draize test, rabbit, eye: 50 ug/24H Severe;
     Draize test, rabbit, eye: 1 mg/24H Severe;
     Draize test, rabbit, skin: 500 mg/24H Severe;
.

CAS# 139-33-3:
     Oral, mouse: LD50 = 2050 mg/kg;
     Oral, rabbit: LD50 = 2300 mg/kg;
     Oral, rat: LD50 = 2 gm/kg;
.

Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7447-40-7: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 10043-35-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 1310-73-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 139-33-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No Data.
Teratogenicity: Not available.
Reproductive Effects: Not available.
Mutagenicity: Not available.
Neurotoxicity: Not available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 7732-18-5 is listed on the TSCA inventory.
     CAS# 7447-40-7 is listed on the TSCA inventory.
     CAS# 10043-35-3 is listed on the TSCA inventory.
     CAS# 1310-73-2 is listed on the TSCA inventory.
     CAS# 139-33-3 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 1310-73-2: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 7447-40-7: immediate.
     CAS # 10043-35-3: immediate, delayed.
     CAS # 1310-73-2: immediate, reactive.
Section 313
     This material contains Potassium chloride (listed as Water Dissociable Nitrate Compounds), 4.0%, (CAS# 7447-40-7) which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 1310-73-2 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 7447-40-7 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 10043-35-3 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 1310-73-2 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 139-33-3 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
      Not available.
Risk Phrases:


Safety Phrases:

     S 24/25 Avoid contact with skin and eyes.

WGK (Water Danger/Protection)

     CAS# 7732-18-5: No information available.
     CAS# 7447-40-7: 1
     CAS# 10043-35-3: 1
     CAS# 1310-73-2: 1
     CAS# 139-33-3: 2
Canada - DSL/NDSL
     CAS# 7732-18-5 is listed on Canada's DSL List.
     CAS# 7447-40-7 is listed on Canada's DSL List.
     CAS# 10043-35-3 is listed on Canada's DSL List.
     CAS# 1310-73-2 is listed on Canada's DSL List.
     CAS# 139-33-3 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 7447-40-7 is not listed on the Canadian Ingredient Disclosure List.
     CAS# 10043-35-3 is listed on the Canadian Ingredient Disclosure List.
     CAS# 1310-73-2 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 3/05/1999
Revision #5 Date: 3/16/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.