Material Safety Data Sheet
n-Propyl isocyanate, 99%

ACC# 46807
Section 1 - Chemical Product and Company Identification
MSDS Name: n-Propyl isocyanate, 99%
Catalog Numbers: AC131600000, AC131600050, AC131600250, AC131601000, AC131605000
Synonyms:

Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
110-78-1 N-PROPYL ISOCYANATE 203-803-6

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear yellow liquid. Flash Point: -1 deg C.
Moisture sensitive.
Target Organs: None known.


Potential Health Effects
Eye: Causes eye irritation. Lachrymator (substance which increases the flow of tears). Lachrymator (substance which increases the flow of tears).
Skin: Causes skin irritation.
Ingestion: Harmful if swallowed. May cause headache. May cause nausea and vomiting.
Inhalation: May be fatal if inhaled. Causes respiratory tract irritation. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May cause an allergic response.
Chronic: Not available.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid immediately. Wash mouth out with water.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Can burn in a fire, releasing toxic vapors. Will burn if involved in a fire. Water reactive. Material will react with water and may release a flammable and/or toxic gas. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Flammable liquid and vapor.
Extinguishing Media: Do NOT use alcohol foams. If water is the only media available, use in flooding amounts. Use carbon dioxide or dry chemical.
Flash Point: -1 deg C ( 30.20 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: Not published.

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage


Handling: Use only in a well-ventilated area. Use spark-proof tools and explosion proof equipment. Do not breathe dust, mist, or vapor. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Do not allow contact with water. Use only in a chemical fume hood.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Keep under a nitrogen blanket. Flammables-area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
N-PROPYL ISOCYANATE none listed none listed none listed

OSHA Vacated PELs: N-PROPYL ISOCYANATE: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear yellow
Odor: Pungent smell
pH: Not available.
Vapor Pressure: 69 mbar @ 20 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 83 - 84 deg C @ 760.00mm Hg
Freezing/Melting Point:<-30 deg C
Decomposition Temperature:Not available.
Solubility: reacts
Specific Gravity/Density:.9080g/cm3
Molecular Formula:C4H7NO
Molecular Weight:85.11

Section 10 - Stability and Reactivity


Chemical Stability: Not available.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents - strong bases - acids - alcohols - amines.
Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 110-78-1: NR0190000
LD50/LC50:
Not available.

Carcinogenicity:
CAS# 110-78-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: N-PROPYL ISOCYANATE N-PROPYL ISOCYANATE
Hazard Class: 6.1 6.1(3)
UN Number: UN2482 UN2482
Packing Group: I I

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 110-78-1 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 110-78-1 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T+ F
Risk Phrases:

     R 11 Highly flammable.
     R 14 Reacts violently with water.
     R 22 Harmful if swallowed.
     R 26 Very toxic by inhalation.
     R 36/37/38 Irritating to eyes, respiratory system and skin.
     R 42 May cause sensitization by inhalation.

Safety Phrases:

     S 16 Keep away from sources of ignition - No smoking.
     S 24/25 Avoid contact with skin and eyes.
     S 38 In case of insufficient ventilation, wear suitable respiratory
     equipment.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 110-78-1: 1
Canada - DSL/NDSL
     CAS# 110-78-1 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, D1A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 110-78-1 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 9/02/1997
Revision #4 Date: 3/25/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.