Material Safety Data Sheet
Bis(2-ethylhexyl) adipate

ACC# 54816
Section 1 - Chemical Product and Company Identification
MSDS Name: Bis(2-ethylhexyl) adipate
Catalog Numbers: AC402460000, AC402460010, AC402460050, AC402462500
Bis(2-ethylhexyl) hexanedioate; Adipic acid, bis(2-ethylhexyl) ester; Dioctyl adipate; DOA plasticizer; Di-2-ethylhexyl adipate.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
103-23-1 Bis(2-ethylhexyl) adipate 99 203-090-1

Section 3 - Hazards Identification


Appearance: clear, colorless liquid.
Caution! May cause eye, skin, and respiratory tract irritation. This is expected to be a low hazard for usual industrial handling.
Target Organs: No data found.

Potential Health Effects
Eye: May cause mild eye irritation.
Skin: May cause mild skin irritation. Not expected to cause an allergic skin reaction.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: Material has a very low vapor pressure at room temperature, so inhalation exposures are not expected unless material is heated or misted.
Chronic: Chronic ingestion may cause liver damage. Reduced growth and increased liver weights were reported with long-term feeding of dioctyl adipate to rats (2 years), while no adverse effects were noted in dogs (1 year). (Monsanto)Dioctyl adipate was administered to rats & mice in a lifetime bioassay sponsored by NTP. Extremely high feed concentrations caused an increased incidence of liver tumors in female mice only. Further studies have shown that the liver tumors observed in mice probably arose from DOA's effect on liver biochemistry; these changes may not occur in humans. Therefore, in the absence of these liver effects, and since DOA is not genotoxic, DOA probably presents a negligible carcinogenic risk to humans at exposure levels of occupational or consumer use. (Eastman)

Section 4 - First Aid Measures

Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Water or foam may cause frothing. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 196 deg C ( 384.80 deg F)
Autoignition Temperature: 350 deg C ( 662.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 1; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Prevent runoff from entering drains, sewers, or streams.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid breathing vapor or mist.
Storage: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Good general ventilation should be sufficient to control airborne levels.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Bis(2-ethylhexyl) adipate none listed none listed none listed

OSHA Vacated PELs: Bis(2-ethylhexyl) adipate: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - Physical and Chemical Properties

Physical State: Liquid
Appearance: clear, colorless
Odor: mild odor
pH: Not applicable.
Vapor Pressure: 0.021 hPa @ 100 deg C
Vapor Density: 12.8 (air=1)
Evaporation Rate:Not available.
Viscosity: 13.7 cps @ 20 deg C
Boiling Point: 417 deg C
Freezing/Melting Point:-67 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:.920 g/ml
Molecular Formula:C22H42O4
Molecular Weight:370.57

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

CAS# 103-23-1: AU9700000
CAS# 103-23-1:
     Oral, mouse: LD50 = 15000 mg/kg;
     Oral, rat: LD50 = 7392 mg/kg;
     Skin, rabbit: LD50 = 16 mL/kg;
     Skin, rabbit: LD50 = 8410 mg/kg/24H;
Eye irritation- practically nonirritating, rabbit 1.4/110.0 (Monsanto). Skin irritation- slightly irritating, rabbit, 24hr exposure, 1.9/8.0 (Monsanto).
CAS# 103-23-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No effects on reproductive performance were found in rats fed dioctyl adipate; reduction in mean body weight gain, reduction in mean pup weights and increased parental liver weights were noted.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: Fish: Fathead Minnow: >1000 mg/l; 96 hr; LC50Fish: Rainbow trout: >1000 mg/l; 96 hr; LC50Fish: Bluegill/Sunfish: >100 mg/l; 96 hr; LC50Water flea Daphnia: 0.66 ppm; 48 hr; EC50 No data available.
Environmental: Dioctyl adipate has a low potential to bioaccumulate in fish.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Shipping Name: Not regulated Not Regulated
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information


     CAS# 103-23-1 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 103-23-1: Not controlled.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
     None of the chemicals in this product are considered highly hazardous by OSHA.
     CAS# 103-23-1 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
Risk Phrases:

     R 40 Limited evidence of a carcinogenic effect.

Safety Phrases:

     S 36/37 Wear suitable protective clothing and gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 103-23-1: 1
Canada - DSL/NDSL
     CAS# 103-23-1 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of Not controlled..
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 103-23-1 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 8/06/1998
Revision #5 Date: 4/27/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.