Material Safety Data Sheet
3,3'-Diaminobenzidine, 99%

ACC# 65650
Section 1 - Chemical Product and Company Identification
MSDS Name: 3,3'-Diaminobenzidine, 99%
Catalog Numbers: AC1112080250, AC112080000, AC112080050, AC112080250
3,3',4,4'-Biphenyltetramine; 3,3',4,4'-Tetraaminobiphenyl.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
91-95-2 3,3'-Diaminobenzidine 99 202-110-6

Section 3 - Hazards Identification


Appearance: brown crystalline powder.
Warning! Causes eye, skin, and respiratory tract irritation. Light sensitive. Hygroscopic (absorbs moisture from the air).
Target Organs: Respiratory system, eyes, skin.

Potential Health Effects
Eye: Causes eye irritation. May cause chemical conjunctivitis.
Skin: Causes irritation with burning pain, itching, and redness.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Inhalation: May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
Chronic: Effects may be delayed.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
3,3'-Diaminobenzidine Skin - potential significant contribution to overall exposure by the cutaneous r oute (listed under Benzidine). none listed (Cancer suspect agent - see 29 CFR 1910.1003) (listed under Benzidine).

OSHA Vacated PELs: 3,3'-Diaminobenzidine: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Crystalline powder
Appearance: brown
Odor: odorless
pH: 7 (1g/l aq. soln.)
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:176.00 - 180.00 deg C
Decomposition Temperature:> 400 deg C
Solubility: 0.55 g/l (20 c)
Specific Gravity/Density:Not available.
Molecular Formula:C12H14N4
Molecular Weight:214.27

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures. Light sensitive. Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid: Incompatible materials, light, dust generation, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

CAS# 91-95-2: DV8750000
CAS# 91-95-2:
     Oral, mouse: LD50 = 1834 mg/kg;

CAS# 91-95-2:

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information


     CAS# 91-95-2 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313
     This material contains 3,3'-Diaminobenzidine (listed as Benzidine), 99%, (CAS# 91-95-2) which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 91-95-2 (listed as Benzidine) is listed as a hazardous air pollut      ant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA. CAS# 91-95-2 is listed as a Priority Pollutant under the Clean Water Act. CAS# 91-95-2 is listed as a Toxic Pollutant under the Clean Water Act.
     None of the chemicals in this product are considered highly hazardous by OSHA.
     CAS# 91-95-2 can be found on the following state right to know lists: California, (listed as Benzidine), New Jersey, (listed as Benzidine), Pennsylvania, (listed as Benzidine), Minnesota, (listed as Benzidine), Massachusetts, (listed as Benzidine).

California Prop 65
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains 3,3'-Diaminobenzidine, listed as `Benzidine', a chemical known to the state of California to cause cancer.
California No Significant Risk Level: CAS# 91-95-2: 0.001 ęg/day NSRL (listed under Benzidine)

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
Risk Phrases:

     R 22 Harmful if swallowed.
     R 36/37/38 Irritating to eyes, respiratory system and skin.
     R 40 Limited evidence of a carcinogenic effect.

Safety Phrases:

     S 37 Wear suitable gloves.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 28A After contact with skin, wash immediately with plenty of water

WGK (Water Danger/Protection)

     CAS# 91-95-2: 2
Canada - DSL/NDSL
     CAS# 91-95-2 is listed on Canada's NDSL List.
Canada - WHMIS
     This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 91-95-2 (listed as Benzidine) is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 10/26/1998
Revision #8 Date: 11/20/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.