Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
10416-59-8	N,O-Bis(trimethylsilyl)acetamide	95+	233-892-7

Section 3 - Hazards Identification

Appearance: colorless to slight yellow low melting solid. Flash Point: 42 deg C.
Danger! Highly flammable. Material is a low melting point solid that may become a liquid above room temperature. Reacts violently with water. Causes burns by all exposure routes. Harmful if swallowed.
Target Organs: Respiratory system, gastrointestinal system, eyes, skin.


Potential Health Effects
Eye: Causes eye burns.
Skin: Causes skin burns. May be harmful if absorbed through the skin.
Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns.
Inhalation: Causes chemical burns to the respiratory tract. May be harmful if inhaled.
Chronic: Animal studies have reported the development of tumors.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Reacts violently with water. Material is a solid at 20°C (68°F) that melts upon moderate heating into a flammable liquid.
Extinguishing Media: Use foam, dry chemical, or carbon dioxide. DO NOT USE WATER!
Flash Point: 42 deg C ( 107.60 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 2; Special Hazard: -W-

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Use a spark-proof tool. Do not expose spill to water. Do not get water inside containers. Do not let this chemical enter the environment.

Section 7 - Handling and Storage

Handling: Do not allow water to get into the container because of violent reaction. Minimize dust generation and accumulation. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Keep away from heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Store in a dry area. Refrigerator/flammables.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
N,O-Bis(trimethylsilyl)acetamide	none listed	none listed	none listed

OSHA Vacated PELs: N,O-Bis(trimethylsilyl)acetamide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties

Physical State: Low melting solid
Appearance: colorless to slight yellow
Odor: none reported
pH: Not available.
Vapor Pressure: 18 mbar @ 50 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 71 - 73 deg C @ 35 mmHg
Freezing/Melting Point:24 deg C
Decomposition Temperature:> 80 deg C
Solubility: Reacts.
Specific Gravity/Density:0.820
Molecular Formula:C8H21NOSi2
Molecular Weight:203.43

Section 10 - Stability and Reactivity

Chemical Stability: Reacts violently with water.
Conditions to Avoid: Incompatible materials, ignition sources, dust generation, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Strong oxidizing agents, acids.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, silicon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:      
CAS# 10416-59-8: AK3000000
LD50/LC50:
Not available.
Oral rat LD50 1580 mg/kg.
Carcinogenicity:
CAS# 10416-59-8: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Tumorigenic effects have been reported in experimental animals.
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	FLAMMABLE SOLIDS, CORROSIVE, ORGANIC, N.	FLAMMABLE SOLIDS, CORROSIVE, ORGANIC, N.
Hazard Class:	4.1	4.1(3)
UN Number:	UN2925	UN2925
Packing Group:	II	II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 10416-59-8 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 10416-59-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     F C
Risk Phrases:
     R 11 Highly flammable.
     R 14 Reacts violently with water.
     R 22 Harmful if swallowed.
     R 34 Causes burns.

Safety Phrases:
     S 16 Keep away from sources of ignition - No smoking.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 30 Never add water to this product.
     S 36 Wear suitable protective clothing.
     S 7/8 Keep container tightly closed and dry.
     S 43A In case of fire, use dry chemical (never use water).

WGK (Water Danger/Protection)
     CAS# 10416-59-8: 1
Canada - DSL/NDSL
     CAS# 10416-59-8 is listed on Canada's NDSL List.
Canada - WHMIS
     This product has a WHMIS classification of B4, E, D1B, F.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 8/18/1998
Revision #14 Date: 2/22/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.