Material Safety Data Sheet
Schiff Reagent

ACC# 88150
Section 1 - Chemical Product and Company Identification

MSDS Name: Schiff Reagent
Catalog Numbers: BP2697-16, BP2697-500, 23245687, 25043
Synonyms:
None Known.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
632-99-5 Basic fuchsin <1 211-189-6
7647-01-0 Hydrogen Chloride <1.0 231-595-7
7681-57-4 Sodium Metabisulfite <1.0 231-673-0
7440-44-0 Activated Charcoal 0.3 % 231-153-3
7732-18-5 Water Balance 231-791-2

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: Clear liquid.
Danger! Corrosive. Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. Potential cancer hazard. May cause cancer based on animal studies.
Target Organs: None known.


Potential Health Effects
Eye: Causes severe eye irritation and burns. May cause chemical conjunctivitis and corneal damage.
Skin: Causes severe skin irritation and burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion: May cause severe and permanent damage to the digestive tract. May cause perforation of the digestive tract. May cause systemic effects. Causes digestive tract irritation with possible burns.
Inhalation: Aspiration may lead to pulmonary edema. May cause systemic effects. Causes severe respiratory tract irritation with possible burns.
Chronic: May cause cancer according to animal studies. Effects may be delayed.

Section 4 - First Aid Measures


Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media: Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes.
Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Basic fuchsin none listed none listed none listed
Hydrogen Chloride 2 ppm Ceiling 50 ppm IDLH 5 ppm Ceiling; 7 mg/m3 Ceiling
Sodium Metabisulfite 5 mg/m3 TWA 5 mg/m3 TWA none listed
Activated Charcoal none listed none listed none listed
Water none listed none listed none listed

OSHA Vacated PELs: Basic fuchsin: No OSHA Vacated PELs are listed for this chemical. Hydrogen Chloride: No OSHA Vacated PELs are listed for this chemical. Sodium Metabisulfite: 5 mg/m3 TWA Activated Charcoal: No OSHA Vacated PELs are listed for this chemical. Water: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: Clear
Odor: Odorless.
pH: 1.3
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:Not available.
Molecular Formula:Not applicable.
Molecular Weight:Not available.

Section 10 - Stability and Reactivity


Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid: Incompatible materials, excess heat.
Incompatibilities with Other Materials: Alcohols and glycols (e.g. butyl alcohol, ethanol, methanol, ethylene glycol), aldehydes (e.g. acetaldehyde, acrolein, chloral, formaldehyde), amides, amines (aliphatic and aromatic, e.g. dimethyl amine, propylamine, pyridine, triethylamine), azo, diazo, and hydrazines (e.g. dimethyl hydrazine, hydrazine, methyl hydrazine), carbamates (e.g. carbanolate, carbofuran), caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), cyanides (e.g. potassium cyanide, sodium cyanide), dithiocarbamates (e.g. ferbam, maneb, metham, thiram), esters (e.g. butyl acetate, ethyl acetate, propyl formate), ethers (e.g. dioxane, furfuran, tetrahydrofuran (THF)), fluorides (inorganic, e.g. ammonium fluoride, calcium fluoride, cesium fluoride), halogenated organics (e.g. dibromoethane, hexachlorobenzene, methyl chloride, trichloroethylene), isocyanates (e.g. methyl isocyanate), ketones (e.g. acetone, acetophenone, MEK, MIBK), mercaptans and other organic sulfides (e.g. butyl mercaptan, carbon disulfide, methanethiol), metals (alkali and alkaline, e.g. cesium, potassium, sodium), metals as powders (e.g. hafnium, raney nickel), metals as non-powders (e.g. brass, bronze, iron), metals and metal compounds (toxic, e.g. beryllium, lead acetate, nickel carbonyl, tetraethyl lead), nitrides (e.g. potassium nitride, sodium nitride), nitriles (e.g. acetonitrile, methyl cyanide), hydrocarbons (aliphatic, unsaturated, e.g. cyclopentene, ethylene, heptene), peroxides and hydroperoxides (organic, e.g. acetyl peroxide, benzoyl peroxide, butyl peroxide, methyl ethyl ketone peroxide), phenols and cresols, organophosphates, phosphothioates (e.g. methylparathion, parathion, phorate, thionazin), sulfides (inorganic, e.g. ferric sulfide, lead sulfide, sodium sulfide), epoxides (e.g. butyl glycidyl ether), combustible and flammable materials (e.g. alkyl resins, asphalt, gasoline, grease, methyl acetone, polystyrene, polyurethane), explosives (e.g. ammonium nitrate, hy.
Hazardous Decomposition Products: Hydrogen chloride, oxides of sulfur, irritating and toxic fumes and gases, sodium oxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 632-99-5: CX9850000      
CAS# 7647-01-0: MW4025000; MW4031000      
CAS# 7681-57-4: UX8225000      
CAS# 7440-44-0: FF5250100      
CAS# 7732-18-5: ZC0110000
LD50/LC50:
Not available.

CAS# 7647-01-0:
     Inhalation, mouse: LC50 = 1108 ppm/1H;
     Inhalation, mouse: LC50 = 20487 mg/m3/5M;
     Inhalation, mouse: LC50 = 3940 mg/m3/30M;
     Inhalation, mouse: LC50 = 8300 mg/m3/30M;
     Inhalation, rat: LC50 = 3124 ppm/1H;
     Inhalation, rat: LC50 = 60938 mg/m3/5M;
     Inhalation, rat: LC50 = 7004 mg/m3/30M;
     Inhalation, rat: LC50 = 45000 mg/m3/5M;
     Inhalation, rat: LC50 = 8300 mg/m3/30M;
     Oral, rabbit: LD50 = 900 mg/kg;
.

CAS# 7681-57-4:
     Dermal, guinea pig: LD50 = >1 gm/kg;
     Draize test, rabbit, eye: 100 mg/24H Mild;
     Draize test, rabbit, skin: 500 mg;
     Oral, rat: LD50 = 1131 mg/kg;
     Skin, rat: LD50 = >2 gm/kg;
.

CAS# 7440-44-0:
.

CAS# 7732-18-5:
     Oral, rat: LD50 = >90 mL/kg;
.

Carcinogenicity:
CAS# 632-99-5:

CAS# 7647-01-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7681-57-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7440-44-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Hydrochloric acid has been shown to produce fetotoxicity in the fetus or embryo of laboratory animals. Specific developmental abnormalities include homeostsis.
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Fish: Pseudomonas putida:

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: HYDROCHLORIC ACID SOLUTION No information available.
Hazard Class: 8
UN Number: UN1789
Packing Group: II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 632-99-5 is listed on the TSCA inventory.
     CAS# 7647-01-0 is listed on the TSCA inventory.
     CAS# 7681-57-4 is listed on the TSCA inventory.
     CAS# 7440-44-0 is listed on the TSCA inventory.
     CAS# 7732-18-5 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 7647-01-0: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     CAS# 7647-01-0: 500 lb TPQ
SARA Codes
     CAS # 7647-01-0: immediate.
     CAS # 7681-57-4: immediate.
     CAS # 7440-44-0: immediate.
Section 313
     This material contains Hydrogen Chloride (CAS# 7647-01-0, <1.0%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 7647-01-0 is listed as a hazardous air pollutant (HAP).



     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 7647-01-0 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     CAS# 7647-01-0 is considered highly hazardous by OSHA.
STATE
     CAS# 632-99-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 7647-01-0 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 7681-57-4 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 7440-44-0 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     C
Risk Phrases:

     R 34 Causes burns.

Safety Phrases:


WGK (Water Danger/Protection)

     CAS# 632-99-5: No information available.
     CAS# 7647-01-0: 1
     CAS# 7681-57-4: 1
     CAS# 7440-44-0: 0
     CAS# 7732-18-5: No information available.
Canada - DSL/NDSL
     CAS# 632-99-5 is listed on Canada's DSL List.
     CAS# 7647-01-0 is listed on Canada's DSL List.
     CAS# 7681-57-4 is listed on Canada's DSL List.
     CAS# 7440-44-0 is listed on Canada's DSL List.
     CAS# 7732-18-5 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 7647-01-0 is listed on the Canadian Ingredient Disclosure List.
     CAS# 7681-57-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 4/24/1998
Revision #9 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.