Material Safety Data Sheet
3-(Methylthio)propionaldehyde, 95% (GC)

ACC# 91777
Section 1 - Chemical Product and Company Identification
MSDS Name: 3-(Methylthio)propionaldehyde, 95% (GC)
Catalog Numbers: AC414920000, AC414920250
Synonyms:
Methional; Beta-(Methylmercapto)propionaldehyde; 3-(Methylmercapto)propionaldehyde; Methylmercaptopropionic Aldehyde.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
3268-49-3 4-Thiapentanal 95 221-882-5

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: colorless liquid. Flash Point: 61 deg C.
Warning! Causes eye, skin, and respiratory tract irritation. Stench. Combustible liquid and vapor. May be harmful if swallowed. May cause central nervous system depression.
Target Organs: Central nervous system.


Potential Health Effects
Eye: Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin: Causes skin irritation. May cause cyanosis of the extremities.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Mercaptans may cause nausea and headache. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), cold extremities and rapid pulse.
Inhalation: Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), cold extremities and rapid pulse. Mercaptans may cause nausea and headache. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
Chronic: Effects may be delayed.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
Flash Point: 61 deg C ( 141.80 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Storage under a nitrogen blanket has been recommended.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
4-Thiapentanal none listed none listed none listed

OSHA Vacated PELs: 4-Thiapentanal: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: faint yellow - colorless
Odor: stench
pH: Not available.
Vapor Pressure: 760 mm Hg @ 165C
Vapor Density: 3.59
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 165-166 deg C @ 11.00mmHg
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:1.0520g/cm3
Molecular Formula:C4H8OS
Molecular Weight:104.17

Section 10 - Stability and Reactivity


Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat, strong oxidants.
Incompatibilities with Other Materials: Strong bases, strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - Toxicological Information


RTECS#:      
CAS# 3268-49-3: UE2285000
LD50/LC50:
CAS# 3268-49-3:
     Draize test, rabbit, eye: 0.01 mL Moderate;
     Draize test, rabbit, skin: 500 uL/24H Severe;
     Draize test, rabbit, skin: 0.5 mL/4H Moderate;
     Inhalation, mouse: LC50 = 5400 mg/m3/2H;
     Inhalation, mouse: LC50 = 5400 mg/m3/2H;
     Inhalation, rat: LC50 = 5820 mg/m3/4H;
     Inhalation, rat: LC50 = 5820 mg/m3/4H;
     Oral, mouse: LD50 = 1620 mg/kg;
     Oral, mouse: LD50 = 1620 mg/kg;
     Oral, rat: LD50 = 700 mg/kg;
     Oral, rat: LD50 = 4400 mg/kg;
     Oral, rat: LD50 = 1.52 mg/kg;
     Skin, rabbit: LD50 = 747
Carcinogenicity:
CAS# 3268-49-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: DOT regulated - small quantity provisions apply (see 49CFR173.4) No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 3268-49-3 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 3268-49-3 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN
Risk Phrases:

     R 36/37/38 Irritating to eyes, respiratory system and skin.
     R 20 Harmful by inhalation.

Safety Phrases:

     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 37/39 Wear suitable gloves and eye/face protection.

WGK (Water Danger/Protection)

     CAS# 3268-49-3: 3
Canada - DSL/NDSL
     CAS# 3268-49-3 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B3, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 7/28/1999
Revision #4 Date: 11/20/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.