Material Safety Data Sheet
Piperazine, anhydrous, 99%
ACC# 92270
Section 1 - Chemical Product and Company Identification |
MSDS Name: Piperazine, anhydrous, 99%
Catalog Numbers:
AC131290000, AC131290025, AC131290050, AC131291000, AC131295000
Synonyms:
Antitren; 1,4-Diethylenediamine; N,N-Diethylenediamine;
Hexahydro-1,4-diazine; Piperazidine; Pyrazine hexahydrate
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
110-85-0 |
Piperazine, anhydrous |
100 | 203-808-3 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: Not available. Flash Point: 82 deg C.
Danger! Corrosive. Causes severe eye and skin
burns. May cause severe allergic respiratory reaction. May cause
severe respiratory and digestive tract irritation with possible
burns. Light sensitive. May cause dermatitis. Hygroscopic (absorbs
moisture from the air).
Target Organs: None.
Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye
burns.
Skin:
May cause skin sensitization, an allergic reaction, which becomes
evident upon re-exposure to this material. Contact with skin causes
irritation and possible burns, especially if the skin is wet or
moist.
Ingestion:
May cause severe gastrointestinal tract irritation with nausea,
vomiting and possible burns.
Inhalation:
May cause irritation of the respiratory tract with burning pain in
the nose and throat, coughing, wheezing, shortness of breath and
pulmonary edema. May cause asthmatic attacks due to allergic
sensitization of the respiratory tract. Causes chemical burns to the
respiratory tract.
Chronic:
Prolonged or repeated skin contact may cause sensitization
dermatitis and possible destruction and/or ulceration. Prolonged or
repeated exposure may cause permanent eye damage. Repeated exposure
may cause allergic respiratory reaction (asthma).
Section 4 - First Aid Measures
|
Eyes:
Get medical aid immediately. Gently lift eyelids and flush continuous
ly with water.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.
Flash Point: 82 deg C ( 179.60 deg F)
Autoignition Temperature: 340 deg C ( 644.00 deg F)
Explosion Limits, Lower:4.00 vol %
Upper: 14.00 vol %
NFPA Rating:
3 - health, 2 - flammability, 0 - instability
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal.
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Do not get on skin
or in eyes. Do not ingest or inhale.
Storage:
Keep away from heat, sparks, and flame. Store in a cool, dry place.
Corrosives area.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Piperazine, anhydrous
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Piperazine, anhydrous:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
|
Physical State: Solid
Appearance: Not available.
Odor: Ammonia-like odor.
pH: Not available.
Vapor Pressure: .8 mm Hg
Vapor Density: 3 (Air=1)
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 145.0 - 146.0 deg C @ 760.00mm Hg
Freezing/Melting Point:108.00 - 110.00 deg C
Decomposition Temperature:Not available.
Solubility: practically insoluble in ether
Specific Gravity/Density:Not available.
Molecular Formula:C4H10N2
Molecular Weight:86.14
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents; strong acids; acid chlorides; acid
anhydrides; light; moisture; dicyanofurazan.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen gas.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 110-85-0:
TK7800000
LD50/LC50:
CAS# 110-85-0:
Draize test,
rabbit, eye: 250 ug Severe;
Draize
test, rabbit, eye: 250 ug/24H Severe;
Inhalation, mouse: LC50 = 5400
mg/m3/2H;
Oral, mouse: LD50 = 600
mg/kg;
Oral, rat: LD50 = 1900
mg/kg;
Skin, rabbit: LD50 = 4
mL/kg;
.
Carcinogenicity:
CAS# 110-85-0:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
Piperazine can combine with nitrites or other nitrosating
agents to form nitrosamines which have been found to cause
cancer in laboratory animals. Piperazine alone was found
to be noncarcinogenic. According to Patty's Industrial
Hygiene and toxicology, Piperazine alone was found to be
noncarcinogenic.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Mutagenicity:
No data available.
Neurotoxicity:
No data available.
Other Studies:
Section 12 - Ecological Information
|
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
PIPERAZINE |
PIPERAZINE |
Hazard Class: |
8 |
8 |
UN Number: |
UN2579 |
UN2579 |
Packing Group: |
III |
III |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 110-85-0 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 110-85-0: immediate, fire.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 110-85-0 can be found on the
following state right to know lists: New Jersey, Pennsylvania,
Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
C
Risk Phrases:
R 34 Causes burns.
R 42/43 May cause sensitization by inhalation and skin contact.
R 52/53 Harmful to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
Safety Phrases:
S 22 Do not breathe dust.
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 61 Avoid release to the environment. Refer to special instructions
/safety data sheets.
WGK (Water Danger/Protection)
CAS# 110-85-0: 2
Canada - DSL/NDSL
CAS# 110-85-0 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of E.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 110-85-0 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 8/24/1997
Revision #4 Date: 11/20/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.