Material Safety Data Sheet
Glycidol

ACC# 93805
Section 1 - Chemical Product and Company Identification
MSDS Name: Glycidol
Catalog Numbers: AC120050000, AC120050050, AC120051000, AC120055000
Synonyms:
2,3-Epoxy-1-propanol; 3-Hydroxy-1,2-epoxypropane; Oxiranemethanol; 3-Hydroxypropylene oxide; Epihydrin alcohol; 2,3-Epoxypropanol; Glycidyl alcohol; Methanol, oxiranyl-.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
556-52-5 Glycidol 96 209-128-3
unlisted

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: colorless liquid. Flash Point: 71 deg C.
Warning! Harmful if inhaled or swallowed. Causes respiratory tract irritation. May impair fertility. Causes eye and skin irritation. May be harmful if absorbed through the skin. Combustible liquid and vapor. Cancer suspect agent. Keep refrigerated. (Store below 4C/39F.)
Target Organs: Central nervous system, respiratory system, eyes, reproductive system, skin.


Potential Health Effects
Eye: Causes eye irritation. Vapors cause eye irritation.
Skin: Causes skin irritation. Substance is rapidly absorbed through the skin. May be harmful if absorbed through the skin.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation: Harmful if inhaled. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Inhalation of vapors causes irritation of the mucous membranes. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
Chronic: May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. Repeated exposure may cause allergic respiratory reaction (asthma). May cause reproductive and fetal effects.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Combustible liquid and vapor.
Extinguishing Media: Do NOT use water directly on fire. Use dry chemical, carbon dioxide, or alcohol-resistant foam.
Flash Point: 71 deg C ( 159.80 deg F)
Autoignition Temperature: 415 deg C ( 779.00 deg F)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat and flame.
Storage: Keep away from heat and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Glycidol 2 ppm TWA 25 ppm TWA; 75 mg/m3 TWA 150 ppm IDLH 50 ppm TWA; 150 mg/m3 TWA
none listed none listed none listed

OSHA Vacated PELs: Glycidol: 25 ppm TWA; 75 mg/m3 TWA : No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.9 mbar @ 25 C
Vapor Density: 2.15 (Air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 160-161 deg C @ 760 mm Hg
Freezing/Melting Point:-54 deg C
Decomposition Temperature:167 deg C
Solubility: Soluble.
Specific Gravity/Density:1.11 @ 20C/4C
Molecular Formula:C3H6O2
Molecular Weight:74.08

Section 10 - Stability and Reactivity


Chemical Stability: May decompose on exposure to moist air or water.
Conditions to Avoid: Ignition sources, excess heat.
Incompatibilities with Other Materials: Metals, strong oxidizing agents, strong acids, bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 556-52-5: UB4375000      
CAS# unlisted.
LD50/LC50:
CAS# 556-52-5:
     Draize test, rabbit, eye: 2 mg/24H Severe;
     Draize test, rabbit, skin: 558 mg/3D Moderate;
     Draize test, rabbit, skin: 100 mg/24H Moderate;
     Inhalation, mouse: LC50 = 450 ppm/4H;
     Inhalation, rat: LC50 = 580 ppm/8H;
     Oral, mouse: LD50 = 431 mg/kg;
     Oral, rat: LD50 = 420 mg/kg;
     Skin, rabbit: LD50 = 1980 mg/kg;
.

CAS# :
.

Carcinogenicity:
CAS# 556-52-5:

CAS# : Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: TOXIC LIQUIDS, ORGANIC, N.O.S. TOXIC LIQUID ORGANIC NOS (GLYCIDOL)
Hazard Class: 6.1 6.1
UN Number: UN2810 UN2810
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 556-52-5 is listed on the TSCA inventory.
     CAS# is not listed on the TSCA inventory. It is for research and development use only.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 556-52-5 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains Glycidol, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T
Risk Phrases:

     R 21/22 Harmful in contact with skin and if swallowed.
     R 23 Toxic by inhalation.
     R 36/37/38 Irritating to eyes, respiratory system and skin.
     R 45 May cause cancer.
     R 60 May impair fertility.

Safety Phrases:

     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 53 Avoid exposure - obtain special instructions before use.

WGK (Water Danger/Protection)

     CAS# 556-52-5: 1
     CAS# : No information available.
Canada - DSL/NDSL
     CAS# 556-52-5 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1B, D2A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 556-52-5 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 3/16/1998
Revision #5 Date: 11/20/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.