Material Safety Data Sheet
2,6-Dimethylaniline

ACC# 94074
Section 1 - Chemical Product and Company Identification
MSDS Name: 2,6-Dimethylaniline
Catalog Numbers: AC115940000, AC115940050, AC115941000, AC115945000
Synonyms: 2,6-Xylidine.
Company Identification:
              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
87-62-7 2,6-Dimethylaniline 99 201-758-7

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: brown liquid. Flash Point: 91 deg C.
Warning! Possible cancer hazard. May cause cancer based on animal data. Harmful if swallowed, inhaled, or absorbed through the skin. Causes eye, skin, and respiratory tract irritation. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Combustible liquid and vapor.
Target Organs: Blood, kidneys, central nervous system, liver, spleen, respiratory system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation. May cause eye injury.
Skin: Causes skin irritation. Harmful if absorbed through the skin. Absorption into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Health hazards similar to aniline but with fewer warning properties and greater toxicity. Symptoms may include anoxia; cyanosis; injury to kidneys, liver, and blood.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. May cause liver damage. Overexposure may cause methemoglobinemia.
Inhalation: Harmful if inhaled. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Causes respiratory tract irritation. Prolonged exposure may result in dizziness and general weakness.
Chronic: Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death. Repeated exposure may cause damage to the spleen. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause blood effects. Animal studies have reported the development of tumors. Limited evidence of a carcinogenic effect.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Containers may explode in the heat of a fire. Combustible liquid and vapor.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: 91 deg C ( 195.80 deg F)
Autoignition Temperature: 490 deg C ( 914.00 deg F)
Explosion Limits, Lower:1.30 vol %
Upper: 6.90 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Use a spark-proof tool. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
2,6-Dimethylaniline 0.5 ppm TWA (inhalable fraction and vapor) (listed under Xylidine).Skin - potential significant contribution to overall exposure by the cutaneous r oute (listed under Xylidine). 2 ppm TWA; 10 mg/m3 TWA (listed under Xylidine).50 ppm IDLH (listed under Xylidine). 5 ppm TWA; 25 mg/m3 TWA (listed under Xylidine).

OSHA Vacated PELs: 2,6-Dimethylaniline: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear - yellow - red - brown
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.2 hPa @ 20 deg C
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 216 deg C @ 760 mmHg
Freezing/Melting Point:10 - 12 deg C
Decomposition Temperature:> 350 deg C
Solubility: Soluble.
Specific Gravity/Density:0.980
Molecular Formula:C8H11N
Molecular Weight:121.18

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials: Acids, acid chlorides, coatings, rubber, halogens, plastics.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 87-62-7: ZE9275000
LD50/LC50:
CAS# 87-62-7:
     Oral, mouse: LD50 = 707 mg/kg;
     Oral, rat: LD50 = 840 mg/kg;
.

Carcinogenicity:
CAS# 87-62-7:


Epidemiology: IARC Group 2B: Proven animal carcinogenic substance of potential relevance to humans.ACGIH has labeled this substance as a confirmed animal carcinogen.Tumorigenic effects have been reported in experimental animals.
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: No data available. No information available.
Environmental: High mobility in soil, however anilines are expected to bind strongly to humus or soil organic matter in soils due to high reactivity of aromatic amine groups. In the atmospheree it should exist solely as vapor in ambient air. Vapor phase is degraded in atmosphere by reaction with photochemically produced hydroxyl radicals. Half life in air is estimated to be 2 hours.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: XYLIDINES, LIQUID XYLIDINES
Hazard Class: 6.1 6.1
UN Number: UN1711 UN1711
Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 87-62-7 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 87-62-7: immediate, delayed, fire.
Section 313
     This material contains 2,6-Dimethylaniline (CAS# 87-62-7, 99%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 87-62-7 can be found on the following state right to know lists: California, (listed as Xylidine), New Jersey, Pennsylvania, Minnesota, (listed as Xylidine), Massachusetts.

California Prop 65
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains 2,6-Dimethylaniline, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: CAS# 87-62-7: 110 ęg/day NSRL

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN N
Risk Phrases:
     R 20/21/22 Harmful by inhalation, in contact with skin and if
     swallowed.
     R 37/38 Irritating to respiratory system and skin.
     R 40 Limited evidence of a carcinogenic effect.
     R 51/53 Toxic to aquatic organisms, may cause long-term adverse
     effects in the aquatic environment.

Safety Phrases:
     S 23 Do not inhale gas/fumes/vapour/spray.
     S 25 Avoid contact with eyes.
     S 36/37 Wear suitable protective clothing and gloves.
     S 61 Avoid release to the environment. Refer to special instructions
     /safety data sheets.

WGK (Water Danger/Protection)
     CAS# 87-62-7: 2
Canada - DSL/NDSL
     CAS# 87-62-7 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B3, D1B, D2A, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 87-62-7 (listed as Xylidine) is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 4/17/1998
Revision #6 Date: 5/07/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.