Material Safety Data Sheet
Benzoyl chloride

ACC# 95451
Section 1 - Chemical Product and Company Identification

MSDS Name: Benzoyl chloride
Catalog Numbers: AC105750000, AC105750010, AC105750025, AC402030000, AC402030050, AC402035000, 40203-0025, O1388-500
Synonyms: Benzene carbonyl chloride; Benzoic acid, chloride; alpha-Chlorobenzaldehyde
Company Identification:
              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
98-88-4 Benzoyl chloride >98 202-710-8

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid. Flash Point: 68 deg C.
Danger! Causes eye and skin burns. Causes digestive and respiratory tract burns. Harmful if absorbed through skin or if inhaled. Combustible liquid and vapor. Material hydrolyzes in contact with moisture/water releasing toxic and corrosive fumes of hydrogen chloride and aqueous hydrochloric acid.
Target Organs: Lungs, eyes, skin.


Potential Health Effects
Eye: Lachrymator (substance which increases the flow of tears). Causes severe eye irritation and burns.
Skin: Harmful if absorbed through the skin. Causes severe skin irritation and burns. AIHA uses a dermal sensitizer notation for this chemical.
Ingestion: May cause severe and permanent damage to the digestive tract.
Inhalation: Harmful if inhaled. Causes chemical burns to the respiratory tract. May cause pulmonary edema and severe respiratory disturbances. Vapors may cause lung injury. Exposures at 2 ppm for 1 minute have been reported as being intolerable.
Chronic: Animal studies have reported the development of tumors by skin contact. Skin and lung tumors were reported in mice after repeated skin contact with benzoyl chloride. These tumors were not considered statistically significant from the

Section 4 - First Aid Measures


Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid immediately.
Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.
Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Combustible liquid and vapor. Use of water will produce irritating and toxic vapors of hydrogen chloride. Hydrochloric acid solutions react with most metals, forming flammable hydrogen gas.
Extinguishing Media: Do NOT get water inside containers. Use dry powder or carbon dioxide.
Flash Point: 68 deg C ( 154.40 deg F)
Autoignition Temperature: 568 deg C ( 1,054.40 deg F)
Explosion Limits, Lower:1.2 vol %
Upper: 4.9 vol %
NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 2; Special Hazard: -W-

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not expose spill to water. Approach spill from upwind.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam. Keep away from heat and flame. Systems and equipment must be scrupulously dry.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store near alkaline substances. Store protected from moisture. Separate from alcohols. Sometimes packaged under dry nitrogen.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Benzoyl chloride 0.5 ppm Ceiling none listed none listed

OSHA Vacated PELs: Benzoyl chloride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: pungent odor - penetrating odor
pH: Not available.
Vapor Pressure: 0.7 mm Hg @ 25 deg C
Vapor Density: 4.88(air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 197.2 deg C
Freezing/Melting Point:-1 deg C
Decomposition Temperature:Not available.
Solubility: decomposes
Specific Gravity/Density:1.21
Molecular Formula:C7H5ClO
Molecular Weight:140.57

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures. Liberates heat and hydrochloric acid on contact with water.
Conditions to Avoid: Ignition sources, contact with water, excess heat, confined spaces.
Incompatibilities with Other Materials: Water, strong oxidizing agents, strong bases, alcohols, amines, dimethyl sulfoxide, attacks metals in the presence of moisture.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, benzoic acid.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 98-88-4: DM6600000
LD50/LC50:
CAS# 98-88-4:
     Inhalation, rat: LC50 = 1870 mg/m3/2H;
     Oral, rat: LD50 = 1900 mg/kg;
.
Dermal, rabbit: LD50 = 790 mg/kg.
Carcinogenicity:
CAS# 98-88-4:


Epidemiology: Based on case reports & epidemiological studies, workers engaged in benzoyl chloride production have been at increased risk to contract lung cancer. But, excess cancer cases were likely due to excessive benzotrichloride exposure & poor industrial hygiene
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: See actual entry in RTECS for complete information.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: BENZOYL CHLORIDE BENZOYL CHLORIDE
Hazard Class: 8 8
UN Number: UN1736 UN1736
Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 98-88-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 98-88-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 98-88-4: immediate, fire, reactive.
Section 313
     This material contains Benzoyl chloride (CAS# 98-88-4, >98%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 98-88-4 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 98-88-4 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     C
Risk Phrases:
     R 34 Causes burns.

Safety Phrases:
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)
     CAS# 98-88-4: 2
Canada - DSL/NDSL
     CAS# 98-88-4 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B3, E, D1B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 98-88-4 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 5/25/1999
Revision #5 Date: 3/16/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.