Material Safety Data Sheet
o-Cresol, 98%

ACC# 95810
Section 1 - Chemical Product and Company Identification
MSDS Name: o-Cresol, 98%
Catalog Numbers: AC110560000, AC110560010
2-Methylphenol; 2-Hydroxytoluene; 2-Cresol; o-Cresylic acid.
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
95-48-7o-Cresol >98 202-423-8

Hazard Symbols:
Risk Phrases:
34 24/25

Section 3 - Hazards Identification


Appearance: white to pale yellow solid. Flash Point: 81 deg C. Danger! Harmful if swallowed. Corrosive. Toxic. Causes eye and skin burns. Causes digestive and respiratory tract burns. Hygroscopic (absorbs moisture from the air). Light sensitive. Harmful if absorbed through the skin. May be fatal if inhaled. May cause liver and kidney damage. Combustible liquid and vapor.
Target Organs: Kidneys, central nervous system, liver.

Potential Health Effects
Eye: May result in corneal injury. Causes eye irritation and burns. May cause conjunctivitis and keratitis.
Skin: May be absorbed through the skin in harmful amounts. Causes severe skin irritation and burns.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause liver and kidney damage. Cresols may cause abnormalities of the central nervous system, respiratory system, spleen and pancreas.
Inhalation: May be fatal if inhaled. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause headache. May cause nausea and possible vomiting.
Chronic: May cause liver and kidney damage. May cause appetite loss, diarrhea, skin abnormalities, and digestive tract disturbances.

Section 4 - First Aid Measures

Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Flash Point: 81 deg C ( 177.80 deg F)
Autoignition Temperature: 598 deg C ( 1,108.40 deg F)
Explosion Limits, Lower:1.30 vol %
Upper: Not available.
NFPA Rating: (estimated) Health: ; Flammability: 2; Instability:

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
o-Cresol5 ppm TWA; skin - potential for cutaneous absorption 2.3 ppm TWA; 10 mg/m3 TWA 250 ppm IDLHnone listed

OSHA Vacated PELs: o-Cresol: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: white to pale yellow
Odor: Phenolic.
pH: Not available.
Vapor Pressure: .25 mm Hg @ 25C
Vapor Density: 3.72 (air=1)
Evaporation Rate:Not available.
Viscosity: 4.75 cP 35 deg C
Boiling Point: 191 deg C @ 760 mm Hg
Freezing/Melting Point:32 - 34 deg C
Decomposition Temperature:Not available.
Solubility: 30.8 g/L @ 40C
Specific Gravity/Density:1.04g/cm3
Molecular Formula:C7H8O
Molecular Weight:108.14

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: High temperatures, light, ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, bases, aliphatic amines, chlorosulfonic acid, oleum.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

CAS# 95-48-7: GO6300000
CAS# 95-48-7:
Draize test, rabbit, eye: 105 mg Severe;
Draize test, rabbit, skin: 524 mg/24H Severe;
Inhalation, mouse: LC50 = 179 mg/m3/2H;
Inhalation, mouse: LC50 = 179 mg/m3;
Inhalation, rat: LC50 = >1220 mg/m3/1H;
Inhalation, rat: LC50 = 29 mg/m3;
Oral, mouse: LD50 = 344 mg/kg;
Oral, mouse: LD50 = 344 mg/kg;
Oral, rabbit: LD50 = 940 mg/kg;
Oral, rat: LD50 = 121 mg/kg;
Oral, rat: LD50 = 1350 mg/kg;
Skin, rabbit: LD50 = 890 mg/kg;
Skin, rabbit: LD50 = 890 mg/kg;
Skin, rat: LD50 = 620 mg/kg;
Skin, rat: LD50 = 620 mg/kg;
CAS# 95-48-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: None.

Section 12 - Ecological Information

Ecotoxicity: No data available. Goldfish (soft water) TLm=49.1-19ppm/24-96H Bluegill (soft water) TLm=22.2-20.8ppm/24-96H Fathead minnow (hard water) TLm=18-13.4ppm/24-96H Guppy (hard water) TLm=18-50ppm/24-96H
Environmental: In air, substance will react with photochemically-produced hydroxyl radicals (day) and nitrate radicals (night). In water, substance will biodegrade within days. Substance is mobile in most soils and will biodegrade.
Physical: No information available.
Other: Please refer to the Handbook of Environmental Fate and Exposure Data (Vol 1) for additional information.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Shipping Name: CRESOLS No information available.
Hazard Class: 6.1
UN Number: UN2076
Packing Group: II

Section 15 - Regulatory Information


CAS# 95-48-7 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 95-48-7: Effective 10/4/82; Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.

CERCLA Hazardous Substances and corresponding RQs
CAS# 95-48-7: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 95-48-7: 1000 lb TPQ (lower threshold); 10000 lb TPQ (upper thres hold)
SARA Codes
CAS # 95-48-7: acute, flammable.
Section 313
This material contains o-Cresol (CAS# 95-48-7, 98%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 95-48-7 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 95-48-7 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product are considered highly hazardous by OSHA.
CAS# 95-48-7 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
Risk Phrases:

R 34 Causes burns.
R 24/25 Toxic in contact with skin and if swallowed.

Safety Phrases:

S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where

WGK (Water Danger/Protection)

CAS# 95-48-7: 2
Canada - DSL/NDSL
CAS# 95-48-7 is listed on Canada's DSL List.
Canada - WHMIS
This product does not have a WHMIS classification.
Canadian Ingredient Disclosure List
CAS# 95-48-7 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 95-48-7: OEL-DENMARK:TWA 5 ppm (22 mg/m3);Skin OEL IN BULGARIA

Section 16 - Additional Information

MSDS Creation Date: 10/15/1997
Revision #4 Date: 3/04/2004

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.