Section 2 - Composition, Information on Ingredients

CAS#	Chemical Name	Percent	EINECS/ELINCS
20816-12-0	OSMIUM TETROXIDE	99.9+	244-058-7

Section 3 - Hazards Identification

Appearance: pale yellow solid.
Danger! Corrosive. Causes eye and skin burns. Causes digestive and respiratory tract burns. Aspiration hazard if swallowed. Can enter lungs and cause damage. May cause adverse reproductive effects.
Target Organs: Kidneys.


Potential Health Effects
Eye: Causes eye burns. May result in corneal injury. May cause blindness.
Skin: Causes skin burns.
Ingestion: Aspiration hazard. Causes gastrointestinal tract burns. May cause kidney damage. Causes cough, sore throat, chest pain, and lightheadedness.
Inhalation: Causes chemical burns to the respiratory tract. May cause bronchopneumonia and possible death.
Chronic: Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated exposure may cause adverse reproductive effects.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Oxidizer. Greatly increases the burning rate of combustible materials. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas.
Extinguishing Media: Do NOT get water inside containers. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating: (estimated) Health: ; Flammability: ; Instability:

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Reduce airborne dust and prevent scattering by moistening with water. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale.
Storage: Do not store near combustible materials. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits

Chemical Name	ACGIH	NIOSH	OSHA - Final PELs
OSMIUM TETROXIDE	0.0002 ppm TWA (as Os); 0.0006 ppm STEL (as Os)	0.0002 ppm TWA; 0.002 mg/m3 TWA 1 mg/m3 IDLH	0.002 mg/m3 TWA (as Os)

OSHA Vacated PELs: OSMIUM TETROXIDE: 0.0002 ppm TWA (as Os); 0.002 mg/m3 TWA (as Os)
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear a chemical apron. Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: pale yellow
Odor: Chlorine-like odor
pH: Not available.
Vapor Pressure: 7 mm Hg @ 20C
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 130 deg C @ 760.00mmHg
Freezing/Melting Point:39.50 - 41.00 deg C
Decomposition Temperature:Not available.
Solubility: 7.24g/100ml (25 c)
Specific Gravity/Density:4.9
Molecular Formula:O4Os
Molecular Weight:254.20

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Excess heat.
Incompatibilities with Other Materials: Combustible materials, Hydrogen chloride, Reducing agents, Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:      
CAS# 20816-12-0: RN1140000
LD50/LC50:
CAS# 20816-12-0:
     Oral, mouse: LD50 = 162 mg/kg;
.

Carcinogenicity:
CAS# 20816-12-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: Paternal Effects: Spermatogenesis and Testes/sperm duct/epididymis, intratesticular-rat TDLo=20336ug/kg.
Mutagenicity: Unscheduled DNA Synthesis: hamster embryo 200umol/L
Neurotoxicity: No information available.
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: No data available. No information available.
Environmental: No information reported.
Physical: No information available.
Other: None.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: CAS# 20816-12-0: waste number P087.
RCRA U-Series: None listed.

Section 14 - Transport Information

	US DOT	Canada TDG
Shipping Name:	TOXIC SOLID, CORROSIVE, INORGANIC, N.O.S.	OSMIUM TETROXIDE
Hazard Class:	6.1	6.1
UN Number:	UN3290	UN2471
Packing Group:	I	I

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 20816-12-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 20816-12-0: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 20816-12-0: immediate, fire.
Section 313
     This material contains OSMIUM TETROXIDE (CAS# 20816-12-0, 99.9+%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     CAS# 20816-12-0 is considered highly hazardous by OSHA.
STATE
     CAS# 20816-12-0 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T C
Risk Phrases:
     R 26/27/28 Very toxic by inhalation, in contact with skin and if
     swallowed.
     R 34 Causes burns.

Safety Phrases:
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 7/9 Keep container tightly closed and in a well-ventilated place.

WGK (Water Danger/Protection)
     CAS# 20816-12-0: 2
Canada - DSL/NDSL
     CAS# 20816-12-0 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1A, E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 20816-12-0 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 3/09/1998
Revision #5 Date: 11/20/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.