Material Safety Data Sheet
Phenolphthalein, Indicator

ACC# 96382
Section 1 - Chemical Product and Company Identification

MSDS Name: Phenolphthalein, Indicator
Catalog Numbers: AC147710000, AC147711000, AC147715000, NC9052846
3,3-bis(4-hydoroxyphenyl)-1(3H)-isobenzofuranone; 3,3-Bis(p-Hydroxyphenyl)Phthalide; Alpha-Di(p-Hydroxyphenyl)Phthalide; Dihydroxy
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
Emergency Number:
For CHEMTREC assistance, call:
For International CHEMTREC assistance, call:

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
77-09-8Phenolphthalein 100 201-004-7

Section 3 - Hazards Identification


Appearance: almost white solid.
Caution! May cause eye and skin irritation. May cause respiratory and digestive tract irritation.
Target Organs: Kidneys.

Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Expected to be a low ingestion hazard.
Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling.
Chronic: May cause kidney injury.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Wash clothing before reuse. Remove contaminated clothing and shoes. Flush skin with plenty of soap and water.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating: (estimated) Health: ; Flammability: ; Instability:

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage

Handling: Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing.
Storage: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Good general ventilation should be sufficient to control airborne levels.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Phenolphthalein none listed none listed none listed

OSHA Vacated PELs: Phenolphthalein: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: almost white
Odor: Odorless.
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:261 - 263 deg C
Decomposition Temperature:Not available.
Solubility: insoluble
Specific Gravity/Density:1.299
Molecular Formula:C20H14O4
Molecular Weight:318.32

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information

CAS# 77-09-8: SM8380000
Not available.

CAS# 77-09-8:

  • California: carcinogen, initial date 5/15/98
  • NTP: Suspect carcinogen
  • IARC: Group 2B carcinogen
    Epidemiology: No information available.
    Teratogenicity: No information available.
    Reproductive Effects: No information available.
    Neurotoxicity: No information available.
    Mutagenicity: No information available.
    Other Studies: No data available.

    Section 12 - Ecological Information

    No information available.

    Section 13 - Disposal Considerations

    Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
    RCRA P-Series: None listed.
    RCRA U-Series: None listed.

    Section 14 - Transport Information

    US DOT Canada TDG
    Shipping Name: Please contact Fisher Scientific for shipping information No information available.
    Hazard Class:
    UN Number:
    Packing Group:

    Section 15 - Regulatory Information


         CAS# 77-09-8 is listed on the TSCA inventory.
    Health & Safety Reporting List
         None of the chemicals are on the Health & Safety Reporting List.
    Chemical Test Rules
         None of the chemicals in this product are under a Chemical Test Rule.
    Section 12b
         None of the chemicals are listed under TSCA Section 12b.
    TSCA Significant New Use Rule
         None of the chemicals in this material have a SNUR under TSCA.
    CERCLA Hazardous Substances and corresponding RQs
         None of the chemicals in this material have an RQ.
    SARA Section 302 Extremely Hazardous Substances
         None of the chemicals in this product have a TPQ.
    SARA Codes
         CAS # 77-09-8: acute.
    Section 313      No chemicals are reportable under Section 313.
    Clean Air Act:
         This material does not contain any hazardous air pollutants.
         This material does not contain any Class 1 Ozone depletors.
         This material does not contain any Class 2 Ozone depletors.
    Clean Water Act:
         None of the chemicals in this product are listed as Hazardous Substances under the CWA.
         None of the chemicals in this product are listed as Priority Pollutants under the CWA.
         None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
         None of the chemicals in this product are considered highly hazardous by OSHA.
         CAS# 77-09-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

    California Prop 65
    The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act:
    WARNING: This product contains Phenolphthalein, a chemical known to the state of California to cause cancer.
    California No Significant Risk Level: None of the chemicals in this product are listed.

    European/International Regulations

    European Labeling in Accordance with EC Directives
    Hazard Symbols:
    Risk Phrases:

         R 40 Limited evidence of a carcinogenic effect.

    Safety Phrases:

         S 24/25 Avoid contact with skin and eyes.

    WGK (Water Danger/Protection)

         CAS# 77-09-8: 1
    Canada - DSL/NDSL
         CAS# 77-09-8 is listed on Canada's DSL List.
    Canada - WHMIS
         WHMIS: Not available.
    Canadian Ingredient Disclosure List

    Section 16 - Additional Information

    MSDS Creation Date: 12/23/1997
    Revision #3 Date: 3/18/2003

    The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.