Material Safety Data Sheet
Diisobutylaluminum hydride(DIBAL-H), 1.0M solution in hexane
ACC# 97212
Section 1 - Chemical Product and Company Identification |
MSDS Name: Diisobutylaluminum hydride(DIBAL-H), 1.0M solution in hexane
Catalog Numbers:
AC183790000, AC183791000, AC183794000, AC183798000
Synonyms:
DIBAL-H
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
110-54-3 |
Hexane |
~85.5 | 203-777-6 |
1191-15-7 |
Diisobutylaluminum hydride |
~14.5 | 214-729-9 |
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: colorless liquid.
Danger! Flammable liquid and vapor. Danger of
serious damage to health by prolonged exposure through inhalation.
Reacts violently with water. Contact with water liberates extremely
flammable gases. Causes burns by all exposure routes. Breathing
vapors may cause drowsiness and dizziness. Pyrophoric. Spontaneously
flammable in air. Toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment. Possible risk of
impaired fertility. Aspiration hazard if swallowed. Can enter lungs
and cause damage.
Target Organs: Blood, central nervous system,
liver, respiratory system, gastrointestinal system, eyes, skin.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. May be harmful if absorbed through the skin.
Ingestion:
Aspiration hazard. Causes gastrointestinal tract burns. May cause
nausea and vomiting. May be harmful if swallowed. May cause lung
damage.
Inhalation:
Prolonged exposure may result in dizziness and general weakness.
Causes chemical burns to the respiratory tract. May be harmful if
inhaled. Aspiration hazard. Inhalation of vapors may cause drowsiness
and dizziness.
Chronic:
Chronic exposure may cause liver damage. Adverse reproductive
effects have been reported in animals. Laboratory experiments have
resulted in mutagenic effects. Chronic exposure may cause blood
effects. Exposure to high concentrations may cause central nervous
system depression. Animal studies have reported the development of
tumors. May impair fertility.
Section 4 - First Aid Measures
|
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid imme
diately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. If
vomiting occurs naturally, have victim lean forward.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do not use
mouth-to-mouth resuscitation if victim ingested or inhaled the
substance; induce artificial respiration with the aid of a pocket
mask equipped with a one-way valve or other proper respiratory
medical device.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn
if involved in a fire. Water reactive. Material will react with
water and may release a flammable and/or toxic gas. Containers may
explode in the heat of a fire. Flammable liquid and vapor. Reacts
violently with water. Contact with water liberates highly flammable
gases.
Extinguishing Media:
Do NOT use carbon dioxide. Use dry chemical to fight fire. DO NOT
USE WATER!
Flash Point: > -22C
Autoignition Temperature: > 225 deg C (> 437.00 deg F)
Explosion Limits, Lower:1.1 (approx)
Upper: 7.5 (approx)
NFPA Rating:
(estimated) Health: 3; Flammability: 3; Instability: 2; Special Hazard: -W-
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Wear a self contained breathing
apparatus and appropriate personal protection. (See Exposure
Controls, Personal Protection section). Remove all sources of
ignition. Use a spark-proof tool. Do not expose spill to water. Do
not get water inside containers. Do not let this chemical enter the
environment.
Section 7 - Handling and Storage
|
Handling:
Do not allow water to get into the container because of violent
reaction. Use spark-proof tools and explosion proof equipment. Do
not get in eyes, on skin, or on clothing. Take precautionary
measures against static discharges. Keep away from heat, sparks and
flame. Do not ingest or inhale. Handle under an inert atmosphere. Do
not allow contact with water. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do
not store in direct sunlight. Store in a tightly closed container.
Flammables-area. Water free area. Store under nitrogen.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility
and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
Hexane
|
50 ppm TWA; Skin - potential significant contribution to overall exposure by the cutaneous r oute
|
50 ppm TWA; 180 mg/m3 TWA 1100 ppm IDLH (10% LEL)
|
500 ppm TWA; 1800 mg/m3 TWA
|
Diisobutylaluminum hydride
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Hexane:
50 ppm TWA; 180 mg/m3 TWA
Diisobutylaluminum hydride:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: colorless
Odor: gasoline-like
pH: Not available.
Vapor Pressure: .150 mm Hg @ 25C
Vapor Density: approx. 3.0
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: > 110 deg C
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:.8000g/cm3
Molecular Formula:Mixture
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
|
Chemical Stability:
Reacts violently with water. Moisture sensitive. Light sensitive.
Conditions to Avoid:
Incompatible materials, light, ignition sources, excess heat,
exposure to moist air or water.
Incompatibilities with Other Materials:
Water, oxidizing agents, acids, alcohols.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, aluminum oxide, aluminum fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 110-54-3:
MN9275000
CAS# 1191-15-7:
BD0710000
LD50/LC50:
CAS# 110-54-3:
Draize test,
rabbit, eye: 10 mg Mild;
Inhalation, mouse: LC50 = 150000
mg/m3/2H;
Inhalation, rat: LC50 =
48000 ppm/4H;
Inhalation, rat:
LC50 = 627000 mg/m3/3M;
Oral, rat:
LD50 = 25 gm/kg;
.
CAS# 1191-15-7:
.
Carcinogenicity:
CAS# 110-54-3:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 1191-15-7:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
Tumorigenic effects have been reported in experimental
animals.
Teratogenicity:
Teratogenic effects have occurred in experimental animals.
Reproductive Effects:
Adverse reproductive effects have occurred in experimental
animals.
Mutagenicity:
Mutagenic effects have occurred in experimental animals.
Neurotoxicity:
No information found
Other Studies:
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
No information available.
Environmental:
No information available.
Physical:
No information available.
Other:
Do not empty into drains.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
Canada TDG |
Shipping Name: |
ORGANOMETALLIC SUBSTANCE, LIQUID, WATER-REACTIVE, FLAMMABLE |
METAL ALKYL HYDRIDES NOS (DIISOBUTYLALUMINUM HYDRIDE) |
Hazard Class: |
4.3 |
4.2(4.3) |
UN Number: |
UN3399 |
UN3050 |
Packing Group: |
I |
I |
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 110-54-3 is listed on the TSCA inventory.
CAS# 1191-15-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 110-54-3: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 110-54-3: immediate, delayed, fire.
Section 313
This material contains Hexane (CAS#
110-54-3, ~85.5%),which is subject to the reporting requirements of
Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 110-54-3 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 110-54-3 can be found on the
following state right to know lists: New Jersey, Pennsylvania,
Minnesota, Massachusetts.
CAS# 1191-15-7 can be found on the
following state right to know lists: New Jersey, Pennsylvania,
Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
F C N
Risk Phrases:
R 11 Highly flammable.
R 14/15 Reacts violently with water liberating extremely flammable
gases.
R 17 Spontaneously flammable in air.
R 35 Causes severe burns.
R 48/20 Harmful : danger of serious damage to health by prolonged
exposure through inhalation.
R 62 Possible risk of impaired fertility.
R 51/53 Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment.
R 65 Harmful: may cause lung damage if swallowed.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S 26 In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
otection.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
S 7/8 Keep container tightly closed and dry.
WGK (Water Danger/Protection)
CAS# 110-54-3: 1
CAS# 1191-15-7: 2
Canada - DSL/NDSL
CAS# 110-54-3 is listed on Canada's DSL List.
CAS# 1191-15-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, E.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 110-54-3 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
|
MSDS Creation Date: 6/03/1999
Revision #6 Date: 8/01/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
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or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.