Material Safety Data Sheet
Diisobutylaluminum hydride(DIBAL-H), 1.0M solution in hexane

ACC# 97212
Section 1 - Chemical Product and Company Identification
MSDS Name: Diisobutylaluminum hydride(DIBAL-H), 1.0M solution in hexane
Catalog Numbers: AC183790000, AC183791000, AC183794000, AC183798000
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
110-54-3 Hexane ~85.5 203-777-6
1191-15-7 Diisobutylaluminum hydride ~14.5 214-729-9

Section 3 - Hazards Identification


Appearance: colorless liquid.
Danger! Flammable liquid and vapor. Danger of serious damage to health by prolonged exposure through inhalation. Reacts violently with water. Contact with water liberates extremely flammable gases. Causes burns by all exposure routes. Breathing vapors may cause drowsiness and dizziness. Pyrophoric. Spontaneously flammable in air. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Possible risk of impaired fertility. Aspiration hazard if swallowed. Can enter lungs and cause damage.
Target Organs: Blood, central nervous system, liver, respiratory system, gastrointestinal system, eyes, skin.

Potential Health Effects
Eye: Causes eye burns.
Skin: Causes skin burns. May be harmful if absorbed through the skin.
Ingestion: Aspiration hazard. Causes gastrointestinal tract burns. May cause nausea and vomiting. May be harmful if swallowed. May cause lung damage.
Inhalation: Prolonged exposure may result in dizziness and general weakness. Causes chemical burns to the respiratory tract. May be harmful if inhaled. Aspiration hazard. Inhalation of vapors may cause drowsiness and dizziness.
Chronic: Chronic exposure may cause liver damage. Adverse reproductive effects have been reported in animals. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause blood effects. Exposure to high concentrations may cause central nervous system depression. Animal studies have reported the development of tumors. May impair fertility.

Section 4 - First Aid Measures

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Potential for aspiration if swallowed. Get medical aid immediately. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If vomiting occurs naturally, have victim lean forward.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Water reactive. Material will react with water and may release a flammable and/or toxic gas. Containers may explode in the heat of a fire. Flammable liquid and vapor. Reacts violently with water. Contact with water liberates highly flammable gases.
Extinguishing Media: Do NOT use carbon dioxide. Use dry chemical to fight fire. DO NOT USE WATER!
Flash Point: > -22C
Autoignition Temperature: > 225 deg C (> 437.00 deg F)
Explosion Limits, Lower:1.1 (approx)
Upper: 7.5 (approx)
NFPA Rating: (estimated) Health: 3; Flammability: 3; Instability: 2; Special Hazard: -W-

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Use a spark-proof tool. Do not expose spill to water. Do not get water inside containers. Do not let this chemical enter the environment.

Section 7 - Handling and Storage

Handling: Do not allow water to get into the container because of violent reaction. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Keep away from heat, sparks and flame. Do not ingest or inhale. Handle under an inert atmosphere. Do not allow contact with water. Use only in a chemical fume hood.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Flammables-area. Water free area. Store under nitrogen.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Hexane 50 ppm TWA; Skin - potential significant contribution to overall exposure by the cutaneous r oute 50 ppm TWA; 180 mg/m3 TWA 1100 ppm IDLH (10% LEL) 500 ppm TWA; 1800 mg/m3 TWA
Diisobutylaluminum hydride none listed none listed none listed

OSHA Vacated PELs: Hexane: 50 ppm TWA; 180 mg/m3 TWA Diisobutylaluminum hydride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties

Physical State: Liquid
Appearance: colorless
Odor: gasoline-like
pH: Not available.
Vapor Pressure: .150 mm Hg @ 25C
Vapor Density: approx. 3.0
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: > 110 deg C
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:.8000g/cm3
Molecular Formula:Mixture
Molecular Weight:Not available.

Section 10 - Stability and Reactivity

Chemical Stability: Reacts violently with water. Moisture sensitive. Light sensitive.
Conditions to Avoid: Incompatible materials, light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials: Water, oxidizing agents, acids, alcohols.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, aluminum oxide, aluminum fumes.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

CAS# 110-54-3: MN9275000      
CAS# 1191-15-7: BD0710000
CAS# 110-54-3:
     Draize test, rabbit, eye: 10 mg Mild;
     Inhalation, mouse: LC50 = 150000 mg/m3/2H;
     Inhalation, rat: LC50 = 48000 ppm/4H;
     Inhalation, rat: LC50 = 627000 mg/m3/3M;
     Oral, rat: LD50 = 25 gm/kg;

CAS# 1191-15-7:

CAS# 110-54-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 1191-15-7: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Tumorigenic effects have been reported in experimental animals.
Teratogenicity: Teratogenic effects have occurred in experimental animals.
Reproductive Effects: Adverse reproductive effects have occurred in experimental animals.
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information

Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

Hazard Class: 4.3 4.2(4.3)
UN Number: UN3399 UN3050
Packing Group: I I

Section 15 - Regulatory Information


     CAS# 110-54-3 is listed on the TSCA inventory.
     CAS# 1191-15-7 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 110-54-3: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 110-54-3: immediate, delayed, fire.
Section 313
     This material contains Hexane (CAS# 110-54-3, ~85.5%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
     CAS# 110-54-3 is listed as a hazardous air pollutant (HAP).

     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
     None of the chemicals in this product are considered highly hazardous by OSHA.
     CAS# 110-54-3 can be found on the following state right to know lists: New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 1191-15-7 can be found on the following state right to know lists: New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     F C N
Risk Phrases:

     R 11 Highly flammable.
     R 14/15 Reacts violently with water liberating extremely flammable
     R 17 Spontaneously flammable in air.
     R 35 Causes severe burns.
     R 48/20 Harmful : danger of serious damage to health by prolonged
     exposure through inhalation.
     R 62 Possible risk of impaired fertility.
     R 51/53 Toxic to aquatic organisms, may cause long-term adverse
     effects in the aquatic environment.
     R 65 Harmful: may cause lung damage if swallowed.
     R 67 Vapours may cause drowsiness and dizziness.

Safety Phrases:

     S 16 Keep away from sources of ignition - No smoking.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 7/8 Keep container tightly closed and dry.

WGK (Water Danger/Protection)

     CAS# 110-54-3: 1
     CAS# 1191-15-7: 2
Canada - DSL/NDSL
     CAS# 110-54-3 is listed on Canada's DSL List.
     CAS# 1191-15-7 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of B2, E.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 110-54-3 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 6/03/1999
Revision #6 Date: 8/01/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.