Material Safety Data Sheet
Aflatoxin B1

ACC# 99137
Section 1 - Chemical Product and Company Identification
MSDS Name: Aflatoxin B1
Catalog Numbers: AC227340000, AC227340010, AC227340100
Synonyms: None known.
Company Identification:
              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
1162-65-8 Aflatoxin B1 98+ 214-603-3

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: yellow powder.
Danger! May be fatal if inhaled, absorbed through the skin or swallowed. Very toxic by inhalation, in contact with skin and if swallowed. Cancer hazard.
Target Organs: Liver.


Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. May be fatal if absorbed through the skin. Toxic in contact with skin.
Ingestion: May be fatal if swallowed. May cause irritation of the digestive tract. Toxic if swallowed.
Inhalation: May be fatal if inhaled. May cause respiratory tract irritation. Toxic if inhaled.
Chronic: May cause cancer in humans.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 4; Flammability: 1; Instability: 1

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Do not store in direct sunlight. Store in a tightly closed container. Store in a dry area. Poison room locked/refrigerator. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Aflatoxin B1 none listed none listed none listed

OSHA Vacated PELs: Aflatoxin B1: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Powder
Appearance: off-white - yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:268 - 269 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble.
Specific Gravity/Density:Not available.
Molecular Formula:C17H12O6
Molecular Weight:312.27

Section 10 - Stability and Reactivity


Chemical Stability: Air sensitive. Light sensitive.
Conditions to Avoid: Incompatible materials, dust generation, exposure to air, direct sunlight..
Incompatibilities with Other Materials: Strong oxidizing agents, acids, alkalies.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 1162-65-8: GY1925000
LD50/LC50:
CAS# 1162-65-8:
     Oral, mouse: LD50 = 9 mg/kg;
     Oral, rabbit: LD50 = 400 ug/kg;
     Oral, rat: LD50 = 4800 ug/kg;
.

Carcinogenicity:
CAS# 1162-65-8:


Epidemiology: No information found
Teratogenicity: TDLo (Oral, rat) = 380 ug/kg/68W-C; Tumorigenic - Carcinogenic by RTECS criteria, Lungs, Thorax, or Respiration - tumors.
Reproductive Effects: No information found
Mutagenicity: Mutation in microorganisms(Salmonella typhimurium) =700 ng/plateMutation in microorganisms(Salmonella typhimurium)=10 ng/plate
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: Bacteria: Phytobacterium phosphoreum: EC50 = 19.44 - 25.66 mg/L; 96 Hr.; Microtox test, 15 degrees C No data available.
Environmental: No information found.
Physical: No information found.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, S TOXINS, EXTRACTED FROM LIVING SOURCES, S
Hazard Class: 6.1 6.1
UN Number: UN3462 UN3462
Packing Group: I I

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 1162-65-8 is not listed on the TSCA inventory. It is for research and development use only.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 1162-65-8 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     T+
Risk Phrases:
     R 26/27/28 Very toxic by inhalation, in contact with skin and if
     swallowed.
     R 45 May cause cancer.

Safety Phrases:
     S 1 Keep locked up.
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
     otection.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).
     S 28A After contact with skin, wash immediately with plenty of water
     .

WGK (Water Danger/Protection)
     CAS# 1162-65-8: No information available.
Canada - DSL/NDSL
None of the chemicals in this product are listed on the DSL or NDSL list.
Canada - WHMIS
     This product has a WHMIS classification of D1A, D2A.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 6/11/1999
Revision #4 Date: 8/29/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.