Material Safety Data Sheet
Poly(vinyl propionate), solution in toluene, average MW ca. 34,000 (GPC)
MSDS Name: Poly(vinyl propionate), solution in toluene, average MW ca. 34,000
Section 1 - Chemical Product and Company Identification
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|| 50-55 ||203-625-9
|| 45-50 ||unlisted
Section 3 - Hazards Identification
Appearance: colorless liquid. Flash Point: 23 deg C.
Warning! Flammable liquid and
vapor. Causes eye, skin, and respiratory tract
irritation. Breathing vapors may cause drowsiness and dizziness. May
be absorbed through intact skin. Aspiration hazard if swallowed. Can
enter lungs and cause damage. Possible risk of harm to the unborn
child. May cause central nervous system depression.
Target Organs: Central nervous system,
respiratory system, eyes, skin.
Potential Health Effects
Causes eye irritation. Vapors may cause eye irritation.
Causes skin irritation. May be absorbed through the skin. Repeated
or prolonged exposure may cause drying and cracking of the skin. Not
expected to cause an allergic skin reaction.
May cause effects similar to those for inhalation exposure.
Aspiration of material into the lungs may cause chemical
pneumonitis, which may be fatal. May cause central nervous system
Causes respiratory tract irritation. Inhalation of high
concentrations (>200 ppm) of toluene are clearly associated with CNS
encephalopathy, headache, depression, lassitude (weakness,
exhaustion), impaired coordination, transient memory loss, and
impaired reaction time.
Prolonged or repeated skin contact may cause defatting and
dermatitis. Repeated exposure in combination with constant, loud
noise can produce hearing loss and dizziness. Chronic hydrocarbon
abuse (for example, sniffing glue or light hydrocarbons such as
contained in this material) has been associated with irregular heart
rhythms and potential cardiac arrest. Toluene abuse has been linked
with kidney disease, as evidenced by blood, protein, & pus in the
urine, accompanied by elevated serum creatinine, decreased urinary
output, & metabolic & renal tubular acidosis. Although kidney
toxicity has not been common in cases of occupational toluene
exposure, there has been at least one report of renal toxicity
following a 40-year occupational toluene exposure. Toluene does not
cause the severe injury to the bone marrow that is characteristic of
Intentional abuse of toluene vapors has been linked to damage of the
brain, liver, kidney and to death. Repeated inhalation exposure of
toluene to animals causes histological changes in the brain,
degeneration of the heart tissue, and possible immune
Section 4 - First Aid Measures
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. If
vomiting occurs naturally, have victim lean forward.
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Causes cardiac sensitization to endogenous catelcholamines which may
lead to cardiac arrhythmias. Do NOT use adrenergic agents such as
epinephrine or pseudoepinephrine.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Water runoff can cause environmental damage. Dike
and collect water used to fight fire. Use water spray to keep
fire-exposed containers cool. Water may be ineffective. Material is
lighter than water and a fire may be spread by the use of water.
Flammable liquid and vapor. Vapors are heavier than air and may
travel to a source of ignition and flash back. Vapors can spread
along the ground and collect in low or confined areas. This liquid
floats on water and may travel to a source of ignition and spread
fire. May accumulate static electricity.
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Solid streams of water may be ineffective and spread material.
Flash Point: 23 deg C ( 73.40 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
(estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Provide ventilation. Use only non-sparking tools and equipment.
Control runoff and isolate discharged material for proper disposal.
Use water spray to cool and disperse vapors and protect personnel.
Section 7 - Handling and Storage
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames. Use only with adequate ventilation.
Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Keep away from sources of ignition. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Separate from oxidizing materials.
Section 8 - Exposure Controls, Personal Protection
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits. Ventilation fans and other electrical
service must be non-sparking and have an explosion-proof design.
||OSHA - Final PELs|
20 ppm TWA
100 ppm TWA; 375 mg/m3 TWA 500 ppm IDLH
200 ppm TWA; 300 ppm Ceiling
OSHA Vacated PELs:
100 ppm TWA; 375 mg/m3 TWA
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Wear chemical splash goggles.
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Liquid
Odor: toluene-like odor
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: >1.0
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Specific Gravity/Density:1.0200 g/cm3
Molecular Weight:Not available.
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures.
Conditions to Avoid:
Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, nitric acid, sulfuric acid.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - Toxicological Information
rabbit, eye: 870 ug Mild;
test, rabbit, eye: 2 mg/24H Severe;
Draize test, rabbit, skin: 435 mg
Draize test, rabbit, skin:
500 mg Moderate;
rabbit, skin: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 400
Inhalation, mouse: LC50 =
LC50 = 19900 mg/m3/7H;
mouse: LC50 = 10000 mg/m3;
Inhalation, rat: LC50 = 49
Oral, rat: LD50 = 636
Skin, rabbit: LD50 = 14100
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
No information available.
In an epidemiologic study of toluene and pregnancy,
occupational exposures to toluene were said to be
associated with an increased incidence of renal, urinary,
gastrointestinal, and cardiac anomalies.Fetotoxicity
(reduced fetal weight), behavioural effects (effects on
learning and memory) and hearing loss (in males) were
observed in the offspring of rats exposed by inhalation to
toluene, in the absence of maternal toxicity.
Many reports of reproductive effects of toluene abuse or
heavy occupational exposure are confounded by mixed
solvent exposure or fetal alcohol syndrome. Women exposed
to toluene in lab work had a 4.7-fold increased risk of
No information available.
No information available.
Section 12 - Ecological Information
No data available.
Bluegill LC50=17 mg/L/24H Shrimp LC50=4.3 ppm/96HFathead minnow
LC50=36.2 mg/L/96HSunfish (fresh water) TLm=1180 mg/L/96H
From soil, substance evaporates and is microbially biodegraded. In
water, substance volatilizes and biodegrades.
Photochemically produced hydroxyl radicals degrade substance.
No information available.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
CAS# 108-88-3: waste
Section 14 - Transport Information
||DOT regulated - small quantity provisions apply (see 49CFR173.4)
||No information available.
Section 15 - Regulatory Information
CAS# 108-88-3 is listed on the TSCA inventory.
CAS# 25035-84-1 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 108-88-3: Effective 10/4/82, Sunset 10/4/92
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 108-88-3: immediate, fire.
This material contains Toluene
(CAS# 108-88-3, 50-55%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 108-88-3 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 108-88-3 is listed as a Hazardous Substance under the CWA.
CAS# 108-88-3 is listed as a Priority Pollutant under the Clean Water
CAS# 108-88-3 is listed as a Toxic Pollutant under the Clean Water
None of the chemicals in this product
are considered highly hazardous by OSHA.
CAS# 108-88-3 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 25035-84-1 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
WARNING: This product contains Toluene, a chemical known to the state
of California to cause developmental reproductive toxicity.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European Labeling in Accordance with EC Directives
R 11 Highly flammable.
R 38 Irritating to skin.
R 48/20 Harmful : danger of serious damage to health by prolonged
exposure through inhalation.
R 63 Possible risk of harm to the unborn child.
R 65 Harmful: may cause lung damage if swallowed.
R 67 Vapours may cause drowsiness and dizziness.
S 36/37 Wear suitable protective clothing and gloves.
S 46 If swallowed, seek medical advice immediately and show this con
tainer or label.
S 62 If swallowed, do not induce vomiting: seek medical advice immed
iately and show this container or label.
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
CAS# 25035-84-1: No information available.
Canada - DSL/NDSL
CAS# 108-88-3 is listed on Canada's DSL List.
CAS# 25035-84-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 108-88-3 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
MSDS Creation Date: 6/23/1999
Revision #6 Date: 11/20/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.